This straightforward 103.5-mile drive from Lewis to Evansville, Indiana, is easily manageable as a single-day trip, taking approximately 2 hours and 13 minutes. With 92% of the journey on highways, it offers a focused driving experience. The estimated fuel cost for this Midwest to Midwest route is around $16, making it an economical option. You'll primarily be on US 41 and State Road 246, with a brief section on East Walnut Street. This trip is ideal for those looking for an efficient way to travel between these two Indiana points without significant detours.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Midpoint
51.8 miles from Lewis, IN
A natural place for your longest stop of the day
, about 1h 7m into the drive
.
Main Roads
Road
Distance
Duration
US 41
95.3 mi
1h 57m
State Road 246
7.3 mi
12m
East Walnut Street
0.7 mi
1m
SR 159
0.1 mi
<1m
East Union Drive
<0.1 mi
<1m
104th Street
<0.1 mi
<1m
Longest stretch:
US 41
— 95.3 mi, about 1h 57m
Turn-by-Turn Driving Directions
Step-by-step road directions between Lewis, IN and Evansville, IN.
1
Start on 104th Street
18 ft·2 sec·104th Street
2
Turn right onto East Union Drive
478 ft·23 sec·East Union Drive
3
Turn right onto SR 159; SR 246
0.1 mi·17 sec·SR 159; SR 246
4
Turn left onto SR 246
7.3 mi·12 min·State Road 246
5
Turn left onto US 41; US 150
42 mi·51 min·US 41; US 150
6
Take the exit onto US 41; US 150
0.2 mi·28 sec·US 41; US 150
7
Merge onto US 41; US 50; US 150
0.9 mi·1 min·US 41; US 50; US 150
8
Keep slight right at fork onto US 41
52 mi·1 hr 4 min·US 41
9
Turn right onto East Walnut Street
0.7 mi·1 min·East Walnut Street
10
Turn right
332 ft·25 sec
11
At end of road, turn right
123 ft·9 sec
12
Arrive at destination
Trip Plan
Given the relatively short duration of about 2 hours and 13 minutes, this trip is perfectly suited for a single day, allowing for flexibility in your departure time. With only 103.5 miles to cover, you can easily make it to Evansville with minimal need for extended stops, though planning for a brief break around the halfway point is always a good idea. Keep an eye on your fuel, with an estimated cost of $16, and consider filling up before leaving Lewis to ensure a smooth journey. A specific tip for this route: pay attention to signage as you transition from US 41 to State Road 246, as this is where the road character changes.
Morning Departure
Leave by 9 AM and you'll arrive before lunch.
Evening Departure
Even a 4 PM departure gets you there before dark in summer.
You can normally do this drive in one day.
You may only need one short stretch break if traffic stays light.
The halfway point lands around 51.8 miles from Lewis, IN, or about 1h 7m into the drive.
The longest continuous stretch on this route runs about 95.3 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 23 miles or 32m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 51.8 miles or 1h 7m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 1h 49m
Traffic, exits, and arrival timing usually matter more near Evansville, IN than in the middle of the route.
Before You Leave
+
Open the route before leaving Lewis, IN so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Lewis, IN
This is one driving day of about 103.5 miles and 2h 13m.
Your first comfortable stop window is around 23 miles from Lewis, IN.
This route can stay practical as a one-day drive if traffic stays reasonable.
The longest stretch is on US 41 for about 95.3 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 9
5 decision points cluster between mile 0 and 103.5 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
5
0 mi into trip|~0m in|East Union Drive
Turn right onto East Union Drive
Navigation decision point
5
0.1 mi into trip|~0m in|SR 159; SR 246
Turn right onto SR 159; SR 246
Navigation decision point
4
0.2 mi into trip|~0m in|SR 246 / State Road 246
Turn left onto SR 246 / State Road 246
Navigation decision point
4
50.8 mi into trip|~1h 6m in|US 41
Keep slight right at fork onto US 41
Highway fork - watch signs carefully
5
103.5 mi into trip|~2h 13m in
At end of road, turn right
Navigation decision point
Fuel & Cost
Regular Gas
$16.18 one way
$32.36 round trip
$3.97/gal25.4 MPG avg36 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.36
$17.77
$35.53
premium
$4.89
$19.92
$39.84
diesel
$5.61
$22.85
$45.70
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$16
Meals
$25–$50
Total
$41–$66
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 36.2 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $11 in charging
· 0 stops
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
31
0
$10.87
$4.97
Efficient EV
25.9
0
$9.06
$4.14
EV Truck/SUV
41.4
0
$14.49
$6.62
Gas CO2
36 kg
EV CO2
12 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 19, 2026
Origin
Lewis, IN
Late night
in Lewis on Tuesday
Local time
4:52 AM
EDT
Current temp
50°F
Unavailable
Live forecast
Destination
Evansville, IN
Late night
in Evansville on Tuesday
Local time
3:52 AM
CDT
Current temp
73°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
1 hour earlier
The destination clock does not match departure time, so double-check hotel check-in windows and late arrival plans.
Temperature spread
23 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
2h 13m on the road
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
George Rogers Clark National Historical Park
National Historical Park
The British flag would not be raised above Fort Sackville Feb. 25, 1779. At 10 A.M., the garrison surrendered to American Colonel George Rogers Clark. His American army, aided by French residents of t...
Park data from the National Park Service API. Alerts update every 2 hours.
More Details
What kind of drive is this?
The drive is predominantly highway-focused, with a substantial 92% of the route utilizing faster roads. You'll experience a long, uninterrupted stretch of 95.3 miles on US 41, which forms the backbone of this journey. While much of the drive is on higher-speed roads, expect some transitions as you navigate through different segments, including State Road 246 and East Walnut Street. This profile suggests a consistent pace for most of your travel time.
92% highway — fuel and pacing are the main things to plan.
12 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 95.3 mi on US 41.
How Hard Is This Drive?
3/10
This is a straightforward highway drive that stays mostly on US 41 and State Road 246. There are only a few real navigation decisions along the way. The trickiest moment comes early in the drive near East Union Drive.
Driving Effort3/10
Easy - simple navigation with a manageable amount of wheel time
Balances navigation complexity with total wheel time.
This is a straightforward 2h 13m drive. You will face about 9 decision points, but nothing that requires special attention if you follow navigation.
Where does it get tricky?
The main spots that need attention: near the start (East Union Drive): Navigation decision point; at 0.1 miles (SR 159; SR 246): Navigation decision point; at 0.2 miles (SR 246 / State Road 246): Navigation decision point.
Evansville is the largest city in Southern Indiana and the third-largest city in the state. It is the county seat of Vanderburgh County and the regional hub for the Indiana, Kentucky, and Illinois tri-state area. In 2010, the city had a population of 117,000. In 2008 the Evansville metropolitan area was home to 350,000 people.
The longest stretch is about 95.3 miles on US 41. The full list of main roads is in the Roads section above.
Yes, with realistic expectations. Build in a stop roughly every 2 hours, have snacks and activities ready, and check the Nearby Places tabs for kid-friendly stops along the way.
The main spots that need attention: near the start (East Union Drive): Navigation decision point; at 0.1 miles (SR 159; SR 246): Navigation decision point; at 0.2 miles (SR 246 / State Road 246): Navigation decision point.
Yes — George Rogers Clark National Historical Park. See the National Parks section for detour distances and tips on detours.
Yes. A round trip is manageable in a single day if you plan a break at Evansville, IN before heading back.
