Largo to Jacksonville is 220.8 miles and takes about 4h 28m via I 75 and US 301, with a fuel budget near $35 and enough daylight to finish in a day. This trip stays within Florida, making it a straightforward drive between two points in the same state. It's a relatively short trip, mostly on major roadways, making it a good option if you want to get to your destination without a lot of fuss. You can expect a consistent pace for most of the drive, with minimal detours or complex navigation.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
110.4 miles from Largo, FL
A natural place for your longest stop of the day
, about 2h 11m into the drive
.
Main Roads
Road
Distance
Duration
I 75
82.3 mi
1h 28m
US 301
75.9 mi
1h 34m
I 275
28.9 mi
36m
I 10
16.8 mi
19m
Ulmerton Road
9.2 mi
15m
Northwest 70th Street
1.5 mi
2m
FL 326
1.1 mi
1m
Seminole Boulevard
1 mi
1m
Longest stretch:
I 75
— 82.3 mi, about 1h 28m
Traffic on I-75
Hour-of-day weekday pattern from 52 FHWA count stations on your route.
Peak
4 PM
~2,814 veh/hr typical
· worst 3,501
Quietest
2 AM
~310 veh/hr
Peak-to-quiet ratio
9.1×
busier at peak than in the quiet hours
12a6anoon6p11p
Averaged across 52 weeks of 2023 FHWA Travel Monitoring Analysis System data. Weekday hours only (Mon–Fri).
Turn-by-Turn Driving Directions
Step-by-step road directions between Largo, FL and Jacksonville, FL.
1
Start on this road
0.1 mi·50 sec·this road
2
At end of road, turn left onto 8th Avenue Southwest
375 ft·13 sec·8th Avenue Southwest
3
Turn right onto US-19 ALT
1.0 mi·1 min·Seminole Boulevard
4
Turn left onto FL 688
8.3 mi·13 min·Ulmerton Road
Use the left lane.
5
Take the ramp onto FL 688
0.9 mi·1 min·Ulmerton Road
Toward I 275 North: Tampa
6
Merge onto I 275
29 mi·36 min·I 275
Use the straight / slight right lanes.
7
Merge onto I 75
82 mi·1 hr 28 min·I 75
Use the straight / slight right lanes.
8
Take the exit
0.2 mi·32 sec
Exit 358Toward FL 326Use the straight / slight right lanes.
9
Turn slight right
144 ft·4 sec
10
Turn slight right onto FL 326
1.1 mi·1 min·FL 326
Use the straight / right lanes.
11
Continue on FL 326
1.5 mi·2 min·Northwest 70th Street
12
Turn left onto US 301; US 441
5.5 mi·6 min·US 301; US 441
Use the left lane.
13
Turn straight onto US 301
52 mi·1 hr 5 min·US 301
Toward North US 301: StarkeUse the straight lane.
14
Continue on US 301
18 mi·22 min·US 301
15
Take the exit
0.9 mi·1 min
Toward I 10 East: Jacksonville
16
Merge onto I 10
17 mi·19 min·I 10
Use the straight / slight right lanes.
17
Take the exit
0.4 mi·33 sec
Toward I 95 South: Jacksonville Beaches, Daytona Beach
18
Keep slight left at fork
0.7 mi·56 sec
Toward I 95 North: International Airport, SavannahUse the slight left / slight right lanes.
19
Merge onto I 95
0.7 mi·1 min·I 95
20
Take the exit onto US 17; FL 228
0.2 mi·26 sec·US 17; FL 228
Exit 353BToward Union Street, Beaver Street
21
Turn straight onto US 17; US 23; FL 228
0.7 mi·1 min·Union Street
Use the straight / left lanes.
22
Arrive at destination
US 17
Trip Plan
This 4.5-hour drive is easily completed in a single day, so you have flexibility with your departure time. Leaving Largo in the morning should get you to Jacksonville by early afternoon, avoiding the worst of potential traffic. With a fuel cost estimated at $35, plan to fill up before you leave or at a convenient stop along I 75. Since the longest stretch between services is about 82.3 miles on I 75, make sure you have adequate fuel before embarking on that segment.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 110.4 miles from Largo, FL, or about 2h 11m into the drive.
The longest continuous stretch on this route runs about 82.3 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 49 miles or 1h 5m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 110.4 miles or 2h 11m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 37m
Traffic, exits, and arrival timing usually matter more near Jacksonville, FL than in the middle of the route.
Before You Leave
+
Open the route before leaving Largo, FL so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Largo, FL
This is one driving day of about 220.8 miles and 4h 28m.
Your first comfortable stop window is around 49 miles from Largo, FL.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on I 75 for about 82.3 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 17
5 decision points cluster between mile 0.1 and 219.9 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
5
0.1 mi into trip|~0m in|8th Avenue Southwest
At end of road, turn left onto 8th Avenue Southwest
Navigation decision point
5
10.4 mi into trip|~18m in|I 275
Merge onto I 275
Merge point - match speed before joining. Lane positioning matters here
Use the straight / slight right lanes.
7
121.6 mi into trip|~2h 23m in
Take the exit toward FL 326
Exit ramp - move to the correct lane early. Lane positioning matters here
Use the straight / slight right lanes.
Exit 358
Toward FL 326
8
218.5 mi into trip|~4h 24m in
Keep slight left at fork toward I 95 North: International Airport, Savannah
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight left / slight right lanes.
Toward I 95 North: International Airport, Savan...
6
219.9 mi into trip|~4h 26m in|US 17; FL 228
Take the exit onto US 17; FL 228 toward Union Street, Beaver Street
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Exit 353B
Toward Union Street, Beaver Street
Fuel & Cost
Regular Gas
$33.42 one way
$66.85 round trip
$3.85/gal25.4 MPG avg77 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.22
$36.68
$73.35
premium
$4.55
$39.55
$79.11
diesel
$4.80
$41.69
$83.38
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$33
Meals
$25–$50
Total
$58–$83
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 77.3 kg one way.
Prices: EIA weekly data, 2026-07-13.
Driving Electric?
About $23 in charging
· 0 stops
· 66% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
66.2
0
$23.18
$10.60
Efficient EV
55.2
0
$19.32
$8.83
EV Truck/SUV
88.3
1
$30.91
$14.13
Gas CO2
77 kg
EV CO2
26 kg (66% less)
Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Jul 18, 2026
Origin
Largo, FL
Evening
in Largo on Monday
Local time
8:16 PM
EDT
Current temp
89°F
Scattered Showers And Thunderstorms
S 13 mph36% chanceLive forecast
Special Weather Statement
Special Weather Statement issued July 18 at 4:21PM EDT by NWS Tallahassee FL
Destination
Jacksonville, FL
Evening
in Jacksonville on Monday
Local time
8:16 PM
EDT
Current temp
95°F
Sunny
S 10 mph6% chanceLive forecast
Special Weather Statement
Special Weather Statement issued July 18 at 4:21PM EDT by NWS Tallahassee FL
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
6 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
4h 28m on the road
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
De Soto National Memorial
National Memorial
In May 1539, Conquistador Hernando de Soto’s army of soldiers, hired mercenaries, craftsmen, and clergy made landfall in Tampa Bay. They were met with fierce resistance of indigenous people protecting...
26 mi from route
~64 min detour
Free
near mile 7.6
Park data from the National Park Service API. Alerts update every 2 hours.
More Details
What kind of drive is this?
You'll spend about 93% of the 220.8 miles on highways. The longest continuous stretch on I 75 is 82.3 miles, so expect extended periods of highway cruising. After the highway portions, you'll transition to US 301, which offers a different driving experience with more local traffic and potential for frequent exits as you approach Jacksonville.
93% highway — fuel and pacing are the main things to plan.
22 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 82.3 mi on I 75.
How Hard Is This Drive?
8/10
This is a straightforward highway drive that stays mostly on I 75 and US 301. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 0.1 miles in near 8th Avenue Southwest.
Driving Effort8/10
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 17 significant decision points across 220.8 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 0.1 miles (8th Avenue Southwest): Navigation decision point; at 10.4 miles (I 275): Merge point - match speed before joining. Lane positioning matters here; at 121.6 miles: Exit ramp - move to the correct lane early. Lane positioning matters here.
Jacksonville occupies one of the most coveted spots on the Atlantic coast. Set amongst abundant beaches and possessing an ideal subtropical climate, its crown jewel is the unique habitat and natural beauty of the St. Johns River. For this reason and more, "The River City" is a popular destination for vacationers looking for a laid-back Sunshine State escape.
Top landmarks
•Fort Caroline — fort in Florida managed by the National Park Service
•Museum of Contemporary Art Jacksonville — museum in Jacksonville, Florida
•Timucuan Ecological and Historic Preserve — wetlands in Florida (U.S.) managed by the National Park Service
Doable as a same-day drive at 4h 28m. Total distance: 220.8 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
4h 28m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (93%). Some complex stretches to watch for.
Frequently Asked Questions
The longest stretch is about 82.3 miles on I 75. The full list of main roads is in the Roads section above.
Yes — we found about 1 rest area or service plaza within a short detour of the route (from OpenStreetMap). See the Rest Stops tab under Nearby Places for locations and mile markers. Plan to stretch, use the bathroom, and top off fluids every 2–3 hours on longer drives.
It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Jacksonville, FL before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. There are 1 rest area along the route for bathroom stops.
The main spots that need attention: at 0.1 miles (8th Avenue Southwest): Navigation decision point; at 10.4 miles (I 275): Merge point - match speed before joining. Lane positioning matters here; at 121.6 miles: Exit ramp - move to the correct lane early. Lane positioning matters here.
Yes — De Soto National Memorial. See the National Parks section for detour distances and tips on detours.
Possible but tiring. At 4.5 hours each way, an in-and-out day trip would put you behind the wheel for 9.0 hours — manageable with a long break at Jacksonville, FL, but most travelers stay overnight.
