Traveling from La Crosse to Saint Germain covers 223.5 miles through the heart of Wisconsin. You should plan for a drive time of approximately 4 hours and 58 minutes, making this a manageable, albeit long, one-day trip. With a fuel cost estimated at $34, it is an affordable way to traverse the Midwest. Since the route is entirely contained within Wisconsin, you will experience a consistent regional feel as you head north. Whether you are heading up for a weekend getaway or a longer vacation, this drive is best tackled in a single day to maximize your time at your destination.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
111.8 miles from La Crosse, WI
A natural place for your longest stop of the day
, about 2h 32m into the drive
.
Main Roads
Road
Distance
Duration
US 51
64.6 mi
1h 18m
I 90
38.6 mi
41m
State Highway 173
34 mi
49m
WI 13
14.3 mi
20m
I 39
12.3 mi
13m
State Highway 34
9.9 mi
13m
County Road D
7.6 mi
12m
WI 16
4.5 mi
8m
Longest stretch:
US 51
— 64.6 mi, about 1h 18m
Turn-by-Turn Driving Directions
Step-by-step road directions between La Crosse, WI and Saint Germain, WI.
1
Start on WI 35
0.7 mi·2 min·West Avenue South
2
Turn right
350 ft·12 sec
3
Turn straight onto CTH F
0.9 mi·2 min·Main Street
4
Turn left onto Losey Boulevard North
0.5 mi·1 min·Losey Boulevard North
5
Continue on WI 16
4.5 mi·8 min·WI 16
6
Take the ramp
0.4 mi·53 sec
7
Merge onto I 90
39 mi·41 min·I 90
8
Take the exit
0.8 mi·55 sec
Exit 45Toward I 94 West: Eau Claire, Saint Paul
9
Merge onto I 94
2.9 mi·3 min·I 94
10
Take the exit
0.3 mi·34 sec
Exit 143Toward US 12, WI 21: Tomah, Necedah
11
Turn right onto WI 21
0.3 mi·33 sec·East McCoy Boulevard
12
Continue on WI 21
4.0 mi·5 min·State Highway 21
13
Turn left onto WI 173
24 mi·33 min·State Highway 173
14
At end of road, turn left onto WI 80; WI 173
1.3 mi·1 min·State Highway 173
15
Continue on WI 80; WI 173
410 ft·8 sec·State Highway 80
16
Turn right onto WI 173
9.1 mi·13 min·State Highway 173
17
Continue on CTH G
2.0 mi·3 min·County Highway G
18
At end of road, turn right onto WI 54
2.1 mi·3 min·State Highway 54
19
Continue on WI 54
1.4 mi·2 min·Letendre Avenue
20
At end of road, turn left onto WI 54; WI 73
1.6 mi·2 min·Wisconsin River Drive
21
Continue on WI 54; WI 73
1.3 mi·1 min·2nd Avenue South
22
Enter roundabout onto WI 54; WI 73
64 ft·1 sec·2nd Avenue South
23
Continue on WI 54; WI 73
0.5 mi·1 min·2nd Avenue South
24
Turn left onto WI 13; WI 73
0.8 mi·1 min·West Riverview Expressway
25
Continue on WI 13; WI 34
14 mi·20 min·WI 13; WI 34
26
Take the ramp onto WI 34
0.3 mi·42 sec·WI 34
27
Merge onto US 10; WI 34
3.8 mi·4 min·US Highway 10
28
Take the exit onto WI 34
0.3 mi·36 sec·WI 34
Exit 208Toward WI 34, CTH P, CTH HH: Knowlton, Stevens Point
29
Turn left onto WI 34
0.1 mi·21 sec·State Highway 134
30
Continue on WI 34
0.2 mi·22 sec·WI 34
31
Continue on WI 34
9.5 mi·13 min·State Highway 34
32
Enter roundabout onto WI 34
132 ft·2 sec·State Highway 34
33
Continue on WI 34
0.3 mi·39 sec·State Highway 34
34
Take the ramp
0.3 mi·41 sec
35
Merge onto I 39; US 51
12 mi·13 min·I 39; US 51
36
Merge onto US 51; WI 29
48 mi·55 min·US 51; WI 29
Use the straight / slight right lanes.
37
Keep slight left at fork onto US 51
17 mi·22 min·US 51
38
Turn right onto CTH D
7.6 mi·12 min·County Road D
39
At end of road, turn left onto WI 47; CTH D
0.6 mi·53 sec·Bradley Street
40
Turn right onto CTH D
3.0 mi·4 min·County Highway D
41
Turn straight onto CTH E
3.9 mi·6 min·County Highway E
42
Turn right onto CTH J
4.4 mi·7 min·County Road J
43
Turn left onto Parkway Road
0.1 mi·28 sec·Parkway Road
44
At end of road, turn left onto WI 70
0.1 mi·15 sec·State Highway 70
45
Arrive at destination
WI 70
Trip Plan
To keep your energy levels high, plan for at least one dedicated stop during your 223.5-mile journey. Since the duration nears five hours, departing early in the morning allows you to reach Saint Germain with plenty of daylight remaining for arrival tasks. Keep an eye on your fuel gauge before entering the longer stretches of US 51, as consistent speeds will impact your consumption. Given the highway-heavy nature of this route, utilizing cruise control on the 64.6-mile stretch can help reduce fatigue. Staying flexible with your timing will ensure you avoid any unexpected traffic delays on the primary interstate sections.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 111.8 miles from La Crosse, WI, or about 2h 32m into the drive.
The longest continuous stretch on this route runs about 64.6 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 49 miles or 1h in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 111.8 miles or 2h 32m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 58m
Traffic, exits, and arrival timing usually matter more near Saint Germain, WI than in the middle of the route.
Before You Leave
+
Open the route before leaving La Crosse, WI so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from La Crosse, WI
This is one driving day of about 223.5 miles and 4h 58m.
Your first comfortable stop window is around 49 miles from La Crosse, WI.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on US 51 for about 64.6 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 29
5 decision points cluster between mile 45.7 and 139.3 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
6
45.7 mi into trip|~56m in
Take the exit toward I 94 West: Eau Claire, Saint Paul
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Exit 45
Toward I 94 West: Eau Claire, Saint Paul
6
49.4 mi into trip|~1h in
Take the exit toward US 12, WI 21: Tomah, Necedah
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Exit 143
Toward US 12, WI 21: Tomah, Necedah
5
93.4 mi into trip|~2h 5m in|WI 54; WI 73 / Wisconsin River Drive
At end of road, turn left onto WI 54; WI 73 / Wisconsin River Drive
Navigation decision point
6
116.1 mi into trip|~2h 38m in|WI 34
Take the exit onto WI 34 toward WI 34, CTH P, CTH HH: Knowlton, Stevens Point
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Merge point - match speed before joining. Lane positioning matters here
Use the straight / slight right lanes.
Fuel & Cost
Regular Gas
$34.94 one way
$69.88 round trip
$3.97/gal25.4 MPG avg78 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.36
$38.36
$76.73
premium
$4.89
$43.01
$86.02
diesel
$5.61
$49.35
$98.69
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$35
Meals
$25–$50
Total
$60–$85
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 78.2 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $23 in charging
· 0 stops
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
67.1
0
$23.47
$10.73
Efficient EV
55.9
0
$19.56
$8.94
EV Truck/SUV
89.4
1
$31.29
$14.30
Gas CO2
78 kg
EV CO2
26 kg (67% less)
Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 14, 2026
Origin
La Crosse, WI
Late night
in La Crosse on Sunday
Local time
2:52 AM
CDT
Current temp
57°F
Patchy Fog
SE 3 mph0% chanceLive forecast
Flood Warning
Flood Warning issued April 14 at 5:40AM CDT until April 19 at 4:00AM CDT by NWS La Crosse WI
Flood Warning
Flood Warning issued April 14 at 5:40AM CDT until April 17 at 7:00AM CDT by NWS La Crosse WI
Destination
Saint Germain, WI
Late night
in Saint Germain on Sunday
Local time
2:52 AM
CDT
Current temp
61°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
4 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
4h 58m on the road
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
Ice Age National Scenic Trail
National Scenic Trail
The Ice Age National Scenic Trail spans 1,200 miles, traverses some of Wisconsin's finest geologic and glacial features, and passes through the ancestral lands of 15 Tribes. The Trail is built, manage...
29 mi from route
~72 min detour
Free
near mile 92.5
Caution: General Advisory — Flooding Possible
Caution: Averill–Kelly Creek Wilderness Segment — Dangerous Ford at New Wood River
Park data from the National Park Service API. Alerts update every 2 hours.
More Details
What kind of drive is this?
This trip is a highway-focused drive, with 86% of your journey spent on high-speed roads. You will rely primarily on I-90, US 51, and State Highway 173 to navigate the distance. Expect to settle in for a long haul, as your longest uninterrupted stretch covers 64.6 miles on US 51. The personality of the road transitions from the interstate segments into more focused highway driving, providing a predictable pace for the majority of your travel. Behind the wheel, you can anticipate a steady flow that emphasizes efficiency over technical maneuvers.
86% highway — fuel and pacing are the main things to plan.
45 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 64.6 mi on US 51.
How Hard Is This Drive?
7/10
This is a straightforward highway drive that stays mostly on US 51 and I 90. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 45.7 miles in.
Driving Effort7/10
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 29 significant decision points across 223.5 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 45.7 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 49.4 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 93.4 miles (WI 54; WI 73 / Wisconsin River Drive): Navigation decision point.
Elevation Profile
Gently rolling terrain
1,642 ft669 ft
Total Climb
1,406 ft
Total Descent
446 ft
Highest Point
1,642 ft
~204.9 mi in
Elevation Range
973 ft
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between La Crosse, WI and Saint Germain, WI, road signs point toward Saint Paul, Necedah, Cth P, Cth Hh: Knowlton and Stevens Point.
La Crosse is a city in the Coulee Region of Southwest Wisconsin on the Mississippi River. It is the county seat of La Crosse County. It's nestled between the river and picturesque bluffs that rise behind it. With a city population of around 50,000 and the metropolitan area just under 100,000, La Crosse offers visitors plenty of activities to do and sights to see, without the overwhelming hustle and bustle of bigger cities.
Doable as a same-day drive at 4h 58m. Total distance: 223.5 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
4h 58m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (86%). Some complex stretches to watch for.
Frequently Asked Questions
The longest stretch is about 64.6 miles on US 51. The full list of main roads is in the Roads section above.
We did not find dedicated rest areas on this route. For a drive this long, plan bathroom and stretch breaks around gas stations, fast-food stops, or small-town downtowns — check the Nearby Places section for options.
It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Saint Germain, WI before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. Dedicated rest areas are limited, so plan gas or food stops as your bathroom breaks.
The main spots that need attention: at 45.7 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 49.4 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 93.4 miles (WI 54; WI 73 / Wisconsin River Drive): Navigation decision point.
Yes — Ice Age National Scenic Trail. See the National Parks section for detour distances and tips on detours.
Possible but tiring. At 5.0 hours each way, an in-and-out day trip would put you behind the wheel for 10.0 hours — manageable with a long break at Saint Germain, WI, but most travelers stay overnight.
