Trip from Knox City, TX to San Antonio, TX
Pin this tripCompiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Oct 23, 2026 · Editorial standards
Drive Time
6h 11m
Distance
333.4 mi
537 km
Drive Score
10/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$50
one way
EV Charging
Unknown
Best Time to Leave
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Knox City, TX
Thomas balabaud
San Antonio, TX
Wikimedia Commons
Trip Overview
Knox City to San Antonio is 333.4 miles and takes about 6h 11m via US 83 and I 10, with a fuel budget near $50 and enough daylight to finish in a day. This trip takes you from the Great Plains region of Texas down toward the southern part of the state. The route is a mix of highway cruising and surface roads, making for a straightforward drive. With a single recommended day, you can comfortably complete this drive without feeling too rushed, making it a good option for a one-day transit.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
166.7 miles from Knox City, TX
A natural place for your longest stop of the day , about 3h 18m into the drive .
Main Roads
| Road | Distance | Duration |
|---|---|---|
| US 83 | 87.3 mi | 1h 31m |
| I 10 | 71.7 mi | 1h 14m |
| Grassmeyer Street | 41.9 mi | 44m |
| Commercial Avenue | 32.5 mi | 35m |
| Ellis Street | 29.4 mi | 31m |
| Union Avenue | 18.2 mi | 26m |
| South 7th Street | 16.5 mi | 18m |
| US 277 | 16.1 mi | 18m |
Traffic on I-10
Hour-of-day weekday pattern from 28 FHWA count stations on your route.
Peak
2 PM
~533 veh/hr typical · worst 963
Quietest
3 AM
~94 veh/hr
Peak-to-quiet ratio
5.7×
busier at peak than in the quiet hours
Averaged across 104 weeks of 2023 FHWA Travel Monitoring Analysis System data. Weekday hours only (Mon–Fri).
Turn-by-Turn Driving Directions
Step-by-step road directions between Knox City, TX and San Antonio, TX.
Start on TX 222
Turn left onto TX 6
Continue on TX 6
Continue on TX 6
Continue on SH 6
Continue on TX 6
Turn right
Take the ramp
Merge onto US 277
Turn slight right onto US 83; US 277
Continue on US 83; US 84
Continue on US 83
Turn left onto US 83
Continue on US 83
Continue on US 83
Take the exit onto US 83
Continue on I 10
Keep slight right at fork onto I 10; US 87
Keep slight right at fork onto I 10; US 87
Take the exit
Turn straight onto North Pecos-La Trinidad
Keep slight right at fork onto North Pecos-La Trinidad
Turn left onto Dolorosa Street
Arrive at destination
Trip Plan
Given the 6h 11m estimated drive time, departing Knox City in the morning is recommended to give you ample daylight. The route is manageable in one day, so you have flexibility with stops. Pay attention to your fuel levels, especially during the 87.3-mile stretch on US 83, as services might be more spread out. The estimated fuel cost is around $50, so plan accordingly. Consider a brief stop around the halfway point to stretch your legs before the final push into San Antonio.
Morning Departure
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Evening Departure
This is a long drive — plan for a morning departure or consider splitting it into two days.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 73 miles or 1h 34m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 166.7 miles or 3h 18m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 5h 6m
Traffic, exits, and arrival timing usually matter more near San Antonio, TX than in the middle of the route.
Before You Leave
Open the route before leaving Knox City, TX so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Knox City, TX
This is one driving day of about 333.4 miles and 6h 11m.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Mid-route town
Meal stop
167 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
Pacing Suggestions
A short stop after about 73 miles helps settle the day before fatigue starts building.
The midpoint is around 166.7 miles from Knox City, TX, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before US 83 if your tank is already low. That segment runs about 87.3 miles.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Stops Along Your Drive
Picked by where they fit in your drive — first break, midpoint reset, final stretch.
Scenic View
Picnic Area
Picnic Area
Kerr County Westbound Rest Area
Kerr County Eastbound Rest Area
Picnic Area
Picnic Area
Picnic Area
Picnic Area
Pilot Travel Center
Love's Travel Stop
Service Plaza
Service Plaza
Service Plaza
Service Plaza
Service Plaza
Service Plaza
Service Plaza
Service Plaza
Service Plaza
Service Plaza
Service Plaza
Service Plaza
QuikTrip
Spanish Governor's Palace
Near the end, right off the route
San Antonio, Texas
Hours: 9 am–5 pm
+12102077527
Visit websiteGO RIO San Antonio River Cruises
Near the end, right off the route
San Antonio, Texas
Hours: 10 am–10 pm
+12102274746
Visit websiteSan Antonio | The Saga
Near the end, right off the route
San Antonio, Texas
Hours: 9–9:30 pm
+12102259800
Visit websiteHemisfair
Near the end, right off the route
San Antonio, Texas
Hours: 5 am–12 pm
+12107094750
Visit websiteSan Antonio Fire Museum
Near the end, right off the route
San Antonio, Texas
Hours: 10 am–3:30 pm
+12103907236
Visit websiteThe Amazing Mirror Maze
Near the end, right off the route
San Antonio, Texas
Hours: 10:30 am–8 pm
+12102242288
Visit websiteSEA LIFE San Antonio
Near the end, right off the route
San Antonio, Texas
Hours: 10 am–5 pm
+12106101160
Visit websiteSan Antonio River Lock & Dam
Near the end, right off the route
San Antonio, Texas
Hours: 9 am–10 pm
+12102271373
Visit websitePlace data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 115 decision points cluster between mile 130.6 and 332.3 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
Turn left onto US 83 / South 7th Street
Lane positioning matters here
Take the exit onto US 83 toward I 10 East: San Antonio
Exit ramp - move to the correct lane early. Lane positioning matters here
Keep slight right at fork onto I 10; US 87
Highway fork - watch signs carefully. Lane positioning matters here
Take the exit toward Santa Rosa Street, Downtown
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Keep slight right at fork onto North Pecos-La Trinidad
Highway fork - watch signs carefully. Lane positioning matters here
Fuel & Cost
Regular Gas
$50.05 one way
$100.10 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.22 | $55.38 | $110.76 |
| premium | $4.57 | $59.92 | $119.84 |
| diesel | $6.28 | $82.38 | $164.76 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$50
Meals
$25–$50
Total
$75–$100
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 116.7 kg one way. Prices: EIA weekly data, 2026-10-19.
Driving Electric?
About $35 in charging · 1 stop · 67% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 100 | 1 | $35.01 | $16.00 |
| Efficient EV | 83.4 | 0 | $29.17 | $13.34 |
| EV Truck/SUV | 133.4 | 1 | $46.68 | $21.34 |
Gas CO2
117 kg
EV CO2
39 kg (67% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Origin
Knox City, TX
Afternoon in Knox City on Friday
Local time
2:34 PM
CDT
Current temp
49°F
Mostly Clear
Destination
San Antonio, TX
Afternoon in San Antonio on Friday
Local time
2:34 PM
CDT
Current temp
55°F
Mostly Cloudy
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
6 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
6h 11m on the road
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
San Antonio Missions National Historical Park
National Historical Park
Welcome to San Antonio Missions, a National Park Service site and the only UNESCO World Heritage Site in Texas. Each mission in the park is a center of community and has been since the early 1700s. Th...
Lyndon B Johnson National Historical Park
National Historical Park
Lyndon B. Johnson National Historical Park tells the story of our 36th president beginning with his ancestors until his final resting place on his beloved LBJ Ranch. This entire "circle of life" gives...
Park data from the National Park Service API. Alerts update every 2 hours.
What kind of drive is this?
This route has a 57% highway share, meaning you'll spend a good portion of your time on faster roads. The longest continuous stretch without a major change in road type is 87.3 miles on US 83. You'll transition from US 83 onto I 10, where you can expect more consistent speeds and potentially denser traffic merging as you approach San Antonio. Beyond the highway segments, expect more typical surface road driving.
How Hard Is This Drive?
7/10
This route mixes highway mileage with some local-road sections near the start or finish. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 130.6 miles in near US 83 / South 7th Street.
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 11 significant decision points across 333.4 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 130.6 miles (US 83 / South 7th Street): Lane positioning matters here; at 218.4 miles (US 83): Exit ramp - move to the correct lane early. Lane positioning matters here; at 312.6 miles (I 10; US 87): Highway fork - watch signs carefully. Lane positioning matters here.
Elevation Profile
Gently rolling terrain
Total Climb
937 ft
Total Descent
1,818 ft
Highest Point
2,097 ft
~238.1 mi in
Elevation Range
1,448 ft
About the Cities
Starting in Knox City, TX
Full guide →Arriving in San Antonio, TX
Full guide →Founded 1718
San Antonio is the second largest city in the state of Texas and the 7th largest in the United States. It's the 24th largest metropolitan area in the country. Visited by more than 31 million annual visitors, San Antonio is a beautiful city at the axis of three different geological terrains: Hill Country, South Texas Plains and Prairie and Lakes. There's a lot to do in this city: fine art museums, historical missions and plenty of amusement parks in addition to great dining and lots of drinking. The culture and people are vibrant and interesting. San Antonio's downtown is one of the most lively in the nation.
Top landmarks
- • Alamo Mission — historic place in San Antonio, Bexar County, Texas
- • San Antonio Missions National Historical Park — historic district in San Antonio, Bexar County, Texas
- • Fort Sam Houston — military base in San Antonio, Texas, United States
City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 6h 11m. Total distance: 333.4 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
6h 11m drive, plan rest stops for pacing.
Scenic Drive
Mixed highway & surface route profile with national parks nearby.
Frequently Asked Questions
How this page is built
Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, USGS 3DEP for elevation, NPS for national parks, and FHWA TMAS for hourly traffic volumes. See our methodology for refresh cadence and limitations.
Was this helpful?
Thanks for your feedback!
Your tip has been submitted. Thanks!
/500
Recent Tips
·
Explore More
Continue From San Antonio, TX
More trips to San Antonio, TX
Explore more options from Knox City, TX or browse trips ending in San Antonio, TX.
Looking for more statewide routes? Browse TX road trips.