Spanning 169.7 miles across Pennsylvania, this journey from Guilford Siding to Pittsburgh is a straightforward trip that typically takes 3 hours and 9 minutes behind the wheel. Because the total duration is quite manageable, you can easily tackle this as a single-day excursion without needing to worry about overnight accommodations. Budgeting around $28 for fuel should cover your transit costs comfortably. You will navigate primarily through Northeast Pennsylvania, moving from the smaller community of Guilford Siding toward the major urban center of Pittsburgh. Since the route relies entirely on local roads rather than interstates, it offers a more personal, ground-level perspective of the state's geography.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Break Rhythm
1 planned break
A short stop every 2 to 3 hours is enough for this drive.
Midpoint
83.3 miles from Guilford Siding, PA
A natural place for your longest stop of the day
, about 1h 54m into the drive
.
Main Roads
Road
Distance
Duration
Pennsylvania Turnpike
104.9 mi
1h 54m
Lincoln Highway
20.8 mi
29m
Lincoln Way West
17.2 mi
25m
Penn-Lincoln Parkway East
13.2 mi
18m
Wayne Road
1.9 mi
3m
Wayne Avenue
1.6 mi
2m
Dwight D Eisenhower Highway
1.5 mi
2m
Guilford Station Road
1.3 mi
4m
Longest stretch:
Pennsylvania Turnpike
— 104.9 mi, about 1h 54m
Turn-by-Turn Driving Directions
Step-by-step road directions between Guilford Siding, PA and Pittsburgh, PA.
1
Start on Church Road
91 ft·11 sec·Church Road
2
Turn sharp left onto Guilford Station Road
1.3 mi·4 min·Guilford Station Road
3
At end of road, turn left onto New Franklin Road
0.6 mi·1 min·New Franklin Road
4
Turn right onto PA 316
1.9 mi·3 min·Wayne Road
5
Continue on PA 316
1.6 mi·2 min·Wayne Avenue
6
Continue on PA 316
0.2 mi·40 sec·South 2nd Street
7
Turn left onto East South Street
0.2 mi·36 sec·East South Street
8
Turn right onto South Water Street
0.3 mi·46 sec·South Water Street
9
Turn left onto West Washington Street
331 ft·15 sec·West Washington Street
10
Turn right onto Cedar Street
347 ft·13 sec·Cedar Street
11
At end of road, turn left onto US 30
0.6 mi·1 min·West Loudon Street
12
At end of road, turn slight left onto US 30
13 mi·20 min·Lincoln Way West
13
Continue on US 30
4.1 mi·5 min·Lincoln Way West
14
Continue on US 30
21 mi·29 min·Lincoln Highway
15
Take the exit
362 ft·9 sec
Toward I 70 West, I 76: Turnpike
16
Continue on I 70
1.5 mi·2 min·Dwight D Eisenhower Highway
17
Keep slight right at fork onto I 70
0.4 mi·46 sec·I 70
Toward I 70 West, I 76 West: Pittsburgh
18
Merge onto I 70; I 76; PATP
105 mi·1 hr 54 min·Pennsylvania Turnpike
19
Take the exit
0.6 mi·2 min
Exit 57Toward I 376 West, US 22: Pittsburgh, MonroevilleUse the slight right lane.
20
Keep slight left at fork
0.2 mi·23 sec
Toward US 22 Business, I 376 West, US 22 West: Monroeville, Pittsburgh
21
Keep slight right at fork
353 ft·8 sec
Toward I 376 West, US 22 West: Pittsburgh
22
Merge onto I 376; US 22
13 mi·18 min·Penn-Lincoln Parkway East
Use the slight left lane.
23
Take the exit
0.2 mi·38 sec
Exit 71BToward Second AvenueUse the straight / slight right lanes.
24
Turn straight onto Second Avenue
0.3 mi·41 sec·Second Avenue
25
At end of road, turn right onto Ross Street
0.2 mi·32 sec·Ross Street
26
Turn left onto Fifth Avenue
352 ft·10 sec·Fifth Avenue
27
Turn right onto Grant Street
513 ft·21 sec·Grant Street
Use the right lane.
28
Arrive at destination
Grant Street
Trip Plan
Since this is a localized, non-highway route, planning one well-timed stop is a smart way to break up the 3-hour journey and stay alert. Aim to depart early in the day to take full advantage of the flexibility that local road travel provides, as traffic patterns on these specific backroads can be less predictable than on major arteries. Keep your fuel gauge in mind before leaving Guilford Siding, as finding consistent service stations is easier when you plan your $28 fuel budget in advance. Most importantly, stay mindful of the turns along Wayne Road and New Franklin Road; because the route is entirely local, taking your time on these winding sections is the safest way to reach Pittsburgh.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 83.3 miles from Guilford Siding, PA, or about 1h 54m into the drive.
The longest continuous stretch on this route runs about 104.9 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 37 miles or 1h in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 83.3 miles or 1h 54m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 2h 52m
Traffic, exits, and arrival timing usually matter more near Pittsburgh, PA than in the middle of the route.
Before You Leave
+
Open the route before leaving Guilford Siding, PA so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Guilford Siding, PA
This is one driving day of about 166.5 miles and 3h 32m.
Your first comfortable stop window is around 37 miles from Guilford Siding, PA.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on Pennsylvania Turnpike for about 104.9 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 20
5 decision points cluster between mile 44.8 and 166.4 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
6
44.8 mi into trip|~1h 11m in
Take the exit toward I 70 West, I 76: Turnpike
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Toward I 70 West, I 76: Turnpike
8
151.7 mi into trip|~3h 9m in
Take the exit toward I 376 West, US 22: Pittsburgh, Monroeville
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight right lane.
Exit 57
Toward I 376 West, US 22: Pittsburgh, Monroevil...
7
152.4 mi into trip|~3h 12m in
Keep slight right at fork toward I 376 West, US 22 West: Pittsburgh
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Toward I 376 West, US 22 West: Pittsburgh
7
165.7 mi into trip|~3h 30m in
Take the exit toward Second Avenue
Exit ramp - move to the correct lane early. Lane positioning matters here
Use the straight / slight right lanes.
Exit 71B
Toward Second Avenue
7
166.4 mi into trip|~3h 32m in|Grant Street
Turn right onto Grant Street
Lane positioning matters here
Use the right lane.
Fuel & Cost
Regular Gas
$27.60 one way
$55.21 round trip
$4.21/gal25.4 MPG avg58 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.61
$30.23
$60.46
premium
$4.93
$32.29
$64.58
diesel
$5.61
$36.76
$73.52
Estimated Tolls: $13.64
Pennsylvania Turnpike
(104.9 mi)$13.64
Toll estimates based on average 2024-2025 rates. EZ-Pass/SunPass discounts may lower the actual cost.
Estimated Trip Cost (one way, 1 person)
Fuel
$28
Tolls
$14
Meals
$25–$50
Total
$66–$91
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 58.3 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $17 in charging
· 0 stops
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
49.9
0
$17.48
$7.99
Efficient EV
41.6
0
$14.57
$6.66
EV Truck/SUV
66.6
0
$23.31
$10.66
Gas CO2
58 kg
EV CO2
19 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 16, 2026
Origin
Guilford Siding, PA
Morning
in Guilford Siding on Sunday
Local time
7:56 AM
EDT
Current temp
45°F
Unavailable
Live forecast
Destination
Pittsburgh, PA
Morning
in Pittsburgh on Sunday
Local time
7:56 AM
EDT
Current temp
73°F
Unavailable
Live forecast
45°F
King, PA
83 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
28 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
3h 32m on the road
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
More Details
What kind of drive is this?
Expect a turn-heavy local drive rather than a monotonous highway cruise, as this route features a 0% highway share. You will navigate a series of secondary roads, including Guilford Station Road, New Franklin Road, and Wayne Road, which demand your full attention and steady focus. Because you are avoiding major interstates entirely, the pace remains consistent but requires more active steering than a standard freeway commute. The character of the road changes as you transition off the smaller local paths, keeping the experience engaging for those who prefer backroad navigation over fast, featureless lanes. Prepare for a hands-on driving experience that prioritizes local transit over high-speed travel.
71% highway — fuel and pacing are the main things to plan.
28 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 104.9 mi on Pennsylvania Turnpike.
How Hard Is This Drive?
9/10
This is a straightforward highway drive that stays mostly on Pennsylvania Turnpike and Lincoln Highway. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 44.8 miles in.
Driving Effort9/10
High effort - long or complex enough to need steady focus all day
Balances navigation complexity with total wheel time.
This is a demanding drive. With 20 significant decision points across 166.5 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 44.8 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 151.7 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 152.4 miles: Highway fork - watch signs carefully. Multiple destination signs - pick the right one.
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
On the drive from Guilford Siding, PA to Pittsburgh, PA, road signs begin pointing toward Monroeville along the way.
The pleasure of Pittsburgh remains a well-kept secret. Though not built up by reputation, the city's unique combination of bridges, steep hills, and broad rivers make it one of the most naturally scenic cities in the country. Cheap food and beer abound in this true sports town and the locals are amazingly friendly. A city of about 303,000 (2021) in Allegheny County, at the center of a metro area of about 2.4 million in southwestern Pennsylvania, Pittsburgh is situated at the confluence of three rivers: the Monongahela and Allegheny Rivers, which meet to form the Ohio River. The city's unique terrain has resulted in an unusual city design and a hodge-podge of unique neighborhood "pockets" with diverse ethnic and architectural heritage.
Doable as a same-day drive at 3h 32m. Total distance: 166.5 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
3h 32m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (71%). Some complex stretches to watch for.
Frequently Asked Questions
The longest stretch is about 104.9 miles on Pennsylvania Turnpike. The full list of main roads is in the Roads section above.
Expect about $13.64 in tolls one way, starting with Pennsylvania Turnpike. Most Northeast and Midwest toll agencies accept E-ZPass; in the West and Texas, transponders like TxTag or FasTrak apply. If you do not have a transponder, cashless tolling plates will mail a bill to the vehicle's registered address — usually with a surcharge, so a rental-car toll pass is often cheaper than paying by mail.
We did not find dedicated rest areas on this route. For a drive this long, plan bathroom and stretch breaks around gas stations, fast-food stops, or small-town downtowns — check the Nearby Places section for options.
It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Pittsburgh, PA before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. Dedicated rest areas are limited, so plan gas or food stops as your bathroom breaks.
The main spots that need attention: at 44.8 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 151.7 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 152.4 miles: Highway fork - watch signs carefully. Multiple destination signs - pick the right one.
Possible but tiring. At 3.5 hours each way, an in-and-out day trip would put you behind the wheel for 7.1 hours — manageable with a long break at Pittsburgh, PA, but most travelers stay overnight.
