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Trip from Greenwood, SC to Spartanburg, SC

Compiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Apr 19, 2026 · Editorial standards

Drive Time

1h 23m

Distance

64 mi

103 km

Drive Score

7/10

Good drive

Same Day?

Yes, doable

Fuel Cost

$10

one way

EV Charging

Unknown

Best Time to Leave

Save up to 20 min
4 AM
1h 17m ★
6 AM
1h 24m
8 AM
1h 37m
10 AM
1h 28m
12 PM
1h 27m
3 PM
1h 29m
5 PM
1h 36m
8 PM
1h 20m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

city in and the county seat of Greenwood County, South Carolina, United States

Greenwood, SC

Wikimedia Commons

Downtown Spartanburg, SC, SC

Spartanburg, SC

Wikimedia Commons

Trip Overview

If you are planning to travel from Greenwood to Spartanburg, you are looking at a 64.2-mile journey through the Southeast that typically takes about 1 hour and 14 minutes. This route is best suited for a quick day trip, as it is short enough to complete in a single outing without needing an overnight stay. You should budget approximately $10 for fuel to cover the trip. Navigating this path involves traveling along local roads like Grace Street, Reynolds Avenue, and Springdale Drive rather than sticking to major interstates. It serves as a straightforward connection between these two South Carolina cities, making it a manageable drive for those who prefer avoiding highway congestion.

Main Roads

Road Distance Duration
I 26 24.9 mi 26m
US 221 24.2 mi 32m
South Church Street 6 mi 10m
Springdale Drive 3.4 mi 4m
Highway 221 2.3 mi 3m
Highway 72 East 1.2 mi 1m
Reynolds Avenue 1 mi 1m
Grace Street 0.3 mi <1m
Longest stretch: I 26 — 24.9 mi, about 26m

Turn-by-Turn Driving Directions

Step-by-step road directions between Greenwood, SC and Spartanburg, SC.

1

Start on SC 72 Business

72 ft · 8 sec · West Cambridge Avenue
2

Turn left onto SC 72 Business

0.3 mi · 34 sec · Grace Street
3

Turn right onto SC 72 Business

1.0 mi · 1 min · Reynolds Avenue
4

Continue on US 221; SC 72

24 mi · 32 min · US 221; SC 72
5

Turn right onto Springdale Drive

3.4 mi · 4 min · Springdale Drive
6

Turn right onto SC 72

1.2 mi · 1 min · Highway 72 East
7

Take the exit

0.3 mi · 37 sec
8

Merge onto I 26

1.4 mi · 1 min · I 26
9

Keep slight right at fork onto I 26

24 mi · 25 min · I 26
Toward Spartanburg Use the straight / slight left lanes.
10

Take the exit

0.3 mi · 33 sec
Exit 28 Toward US 221: Spartanburg-South, Moore Use the slight right lane.
11

Turn straight onto US 221

2.3 mi · 3 min · Highway 221
12

Continue on US 221

6.0 mi · 10 min · South Church Street
13

Arrive at destination

US 221; SC 56

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

city in Laurens County, South Carolina, United States

Mid-route town

Meal stop

Clinton, SC

32 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Popular next leg

Clinton, SC to Spartanburg, SC

35.4 mi · 46m

Pacing Suggestions

Cross Hill, SC

Fuel and coffee

A short stop after about 14 miles helps settle the day before fatigue starts building.

Clinton, SC

Meal break

The midpoint is around 32 miles from Greenwood, SC, which is a good place for a longer meal and fuel stop.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Heads-up: tricky spots

5 of 8

5 decision points cluster between mile 0 and 55.4 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.

4
0 mi into trip | ~0m in | SC 72 Business / Grace Street

Turn left onto SC 72 Business / Grace Street

Navigation decision point

4
29 mi into trip | ~39m in | SC 72 / Highway 72 East

Turn right onto SC 72 / Highway 72 East

Navigation decision point

5
30.2 mi into trip | ~41m in

Take the exit

Exit ramp - move to the correct lane early

7
31.9 mi into trip | ~43m in | I 26

Keep slight right at fork onto I 26 toward Spartanburg

Highway fork - watch signs carefully. Lane positioning matters here

Use the straight / slight left lanes. Toward Spartanburg
8
55.4 mi into trip | ~1h 8m in

Take the exit toward US 221: Spartanburg-South, Moore

Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one

Use the slight right lane. Exit 28 Toward US 221: Spartanburg-South, Moore

Fuel & Cost

Regular Gas

$10.01 one way

$20.02 round trip

$3.97/gal 25.4 MPG avg 22 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.34 $10.94 $21.89
premium $4.70 $11.85 $23.69
diesel $5.61 $14.13 $28.26

No toll roads detected on this route.

Drive Cost (one way)

Fuel

$10

Estimated CO2 emission: 22.4 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $7 in charging · 0 stops · 68% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 19.2 0 $6.72 $3.07
Efficient EV 16 0 $5.60 $2.56
EV Truck/SUV 25.6 0 $8.96 $4.10

Gas CO2

22 kg

EV CO2

7 kg (68% less)

This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Apr 18, 2026

Origin

Greenwood, SC

Late night in Greenwood on Sunday

Local time

4:13 AM

EDT

Current temp

86°F

Unavailable

Live forecast

Destination

Spartanburg, SC

Late night in Spartanburg on Sunday

Local time

4:13 AM

EDT

Current temp

86°F

Unavailable

Live forecast

48°F

Clinton, SC

32 mi in

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

Very similar conditions

Both ends of the route are sitting at about the same temperature right now.

Road read

1h 23m on the road

Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

What kind of drive is this?

Expect a turn-heavy local drive that keeps you engaged behind the wheel. Unlike a monotonous interstate slog, this route features a 0% highway share, meaning you will spend the entire 64.2 miles navigating local surface streets. Because the longest stretch is 0 miles on Grace Street, the path requires constant attention to turns and transitions between roads. You will find that the personality of the drive remains technical rather than fast-paced. It is a practical alternative to high-speed travel, offering a consistent, hands-on experience through the South Carolina landscape.

82% highway — fuel and pacing are the main things to plan.
13 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 24.9 mi on I 26.

How Hard Is This Drive?

4/10

This is a straightforward highway drive that stays mostly on I 26 and US 221. There are only a few real navigation decisions along the way. The trickiest moment comes early in the drive near SC 72 Business / Grace Street.

Driving Effort 4/10

Easy - simple navigation with a manageable amount of wheel time

Balances navigation complexity with total wheel time.

This is a straightforward 1h 23m drive. You will face about 8 decision points, but nothing that requires special attention if you follow navigation.

Where does it get tricky?

The main spots that need attention: near the start (SC 72 Business / Grace Street): Navigation decision point; at 29 miles (SC 72 / Highway 72 East): Navigation decision point; at 30.2 miles: Exit ramp - move to the correct lane early.

Towns Mentioned on Route Signs

Based on OSRM destination-sign hints, not a full list of every settlement the road passes.

On the drive from Greenwood, SC to Spartanburg, SC, road signs begin pointing toward Moore along the way.

Moore

55.4 mi in | ~1h 8m

About the Cities

Starting in Greenwood, SC

Full guide →

Greenwood is the county seat of Greenwood County in Old 96 District.

Arriving in Spartanburg, SC

Full guide →

Spartanburg is both a county and city in Upcountry South Carolina.

City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).

Who Is This Route For?

Weekend Trip

Doable as a same-day drive at 1h 23m. Total distance: 64 miles.

Family Friendly

Moderate complexity with 0 natural rest stops along the way.

Solo Traveler

1h 23m drive, comfortable solo distance.

EV Driver

0 DC fast chargers along the route. Coverage: unknown.

First-Time Driver

Mostly highway driving (82%). Straightforward navigation.

Frequently Asked Questions

The longest stretch is about 24.9 miles on I 26. The full list of main roads is in the Roads section above.

Yes. At under 2 hours behind the wheel, this works well for families — plan one quick stop if you have younger kids.

The main spots that need attention: near the start (SC 72 Business / Grace Street): Navigation decision point; at 29 miles (SC 72 / Highway 72 East): Navigation decision point; at 30.2 miles: Exit ramp - move to the correct lane early.

Yes — Cowpens National Battlefield. See the National Parks section for detour distances and tips on detours.

Yes. A round trip is manageable in a single day if you plan a break at Spartanburg, SC before heading back.

How this page is built

Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, and NPS for national parks. See our methodology for refresh cadence and limitations.

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Explore More

Explore more options from Greenwood, SC or browse trips ending in Spartanburg, SC.

Looking for more statewide routes? Browse SC road trips.