If you are planning a trip from Georgetown to Florence, you can expect a manageable 81.2-mile journey that typically takes about 1 hour and 56 minutes. This route is perfectly suited for a single-day excursion, allowing you to reach your destination without the need for an overnight stay. You will primarily navigate via US Highway 521, South Ron McNair Boulevard, and North Williamsburg County Highway. Budgeting approximately $13 for fuel should comfortably cover your travel costs for this trip across the Southeast. Because the drive is relatively short, it offers a straightforward transition between these two South Carolina locations, making it a reliable choice for travelers who prefer to stay on the move rather than dragging out the commute.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Midpoint
40.6 miles from Georgetown, SC
A natural place for your longest stop of the day
, about 52m into the drive
.
Main Roads
Road
Distance
Duration
US Highway 521
17.4 mi
19m
South Ron McNair Boulevard
15.2 mi
24m
North Williamsburg County Highway
10.6 mi
13m
Highmarket Street
9.1 mi
12m
Georgetown Highway
7.8 mi
9m
South Irby Street
7 mi
9m
Martin Luther King Jr Avenue
6.1 mi
10m
South Church Street
2.7 mi
5m
Longest stretch:
US Highway 521
— 17.4 mi, about 19m
Turn-by-Turn Driving Directions
Step-by-step road directions between Georgetown, SC and Florence, SC.
1
Start on US 17 Alternate; US 521
9.1 mi·12 min·Highmarket Street
2
Continue on US 521
6.2 mi·7 min·Georgetown Highway
3
Continue on US 521 Bus
1.7 mi·2 min·Georgetown Highway
4
Continue on US 521 Bus
1.7 mi·2 min·East Main Street
5
Continue on US 521
17 mi·19 min·US Highway 521
6
Turn right onto SC 377
6.1 mi·10 min·Martin Luther King Jr Avenue
7
At end of road, turn right onto SC 261
0.3 mi·32 sec·East Main Street
8
Turn left onto County Road S-45-186
1.6 mi·3 min·Eastland Avenue
9
Turn left onto Dennis Avenue
0.3 mi·46 sec·Dennis Avenue
10
At end of road, turn right onto US 52
11 mi·13 min·North Williamsburg County Highway
11
Continue on US 52
15 mi·24 min·South Ron McNair Boulevard
12
Continue on US 52
7.0 mi·9 min·South Irby Street
13
Turn right onto US 301
1.3 mi·2 min·Freedom Boulevard
14
Turn left onto South Church Street
2.7 mi·5 min·South Church Street
15
Turn left
57 ft·4 sec
Use the left lane.
16
Turn slight left
126 ft·14 sec
17
At end of road, turn left
44 ft·5 sec
18
Turn right
50 ft·3 sec
19
Arrive at destination
Trip Plan
Since this is a quick trip, you have plenty of flexibility to plan your departure around your personal schedule. While the 1 hour and 56 minute duration is short, the turn-heavy nature of the route means you should stay alert throughout the entire 81.2-mile drive. Consider filling your tank before you leave Georgetown to ensure you don't have to worry about fuel stops along the way. Because there are no mandatory stops listed, you can easily adjust your pace to suit your preferences without feeling rushed. A helpful tip for this route is to keep a close eye on your navigation as you transition between North Williamsburg County Highway and your final approach, as the frequent turns can be easy to miss if you aren't paying close attention.
Morning Departure
Leave by 9 AM and you'll arrive before lunch.
Evening Departure
Even a 4 PM departure gets you there before dark in summer.
You can normally do this drive in one day.
You may only need one short stretch break if traffic stays light.
The halfway point lands around 40.6 miles from Georgetown, SC, or about 52m into the drive.
The longest continuous stretch on this route runs about 17.4 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 18 miles or 23m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 40.6 miles or 52m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 1h 36m
Traffic, exits, and arrival timing usually matter more near Florence, SC than in the middle of the route.
Before You Leave
+
Open the route before leaving Georgetown, SC so your first major turns are already loaded.
Day 1
Settle into the route from Georgetown, SC
This is one driving day of about 81.2 miles and 1h 56m.
Your first comfortable stop window is around 18 miles from Georgetown, SC.
This route can stay practical as a one-day drive if traffic stays reasonable.
The longest stretch is on US Highway 521 for about 17.4 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 10
5 decision points cluster between mile 42.2 and 81.2 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
5
42.2 mi into trip|~55m in|SC 261 / East Main Street
At end of road, turn right onto SC 261 / East Main Street
Navigation decision point
5
44.3 mi into trip|~1h in|US 52 / North Williamsburg County Highway
At end of road, turn right onto US 52 / North Williamsburg County Highway
Navigation decision point
5
81.1 mi into trip|~1h 55m in
Turn left
Lane positioning matters here
Use the left lane.
5
81.2 mi into trip|~1h 55m in
At end of road, turn left
Navigation decision point
5
81.2 mi into trip|~1h 56m in
Turn right
Navigation decision point
Fuel & Cost
Regular Gas
$12.70 one way
$25.40 round trip
$3.97/gal25.4 MPG avg28 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.34
$13.88
$27.77
premium
$4.70
$15.03
$30.06
diesel
$5.61
$17.93
$35.86
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$13
Meals
$25–$50
Total
$38–$63
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 28.4 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $9 in charging
· 0 stops
· 64% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
24.4
0
$8.53
$3.90
Efficient EV
20.3
0
$7.10
$3.25
EV Truck/SUV
32.5
0
$11.37
$5.20
Gas CO2
28 kg
EV CO2
10 kg (64% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 20, 2026
Origin
Georgetown, SC
Late night
in Georgetown on Tuesday
Local time
5:08 AM
EDT
Current temp
83°F
Unavailable
Live forecast
Destination
Florence, SC
Late night
in Florence on Tuesday
Local time
5:08 AM
EDT
Current temp
85°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
2 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
1h 56m on the road
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
More Details
What kind of drive is this?
Expect a turn-heavy local drive rather than a monotonous interstate cruise on this trek toward Florence. With only 21% of the route consisting of major highway travel, you will spend most of your time navigating local roads that require your full attention. The longest uninterrupted stretch you will encounter is a 17.4-mile segment on US Highway 521, which provides a brief reprieve from the more frequent turns found elsewhere. As you progress through the South Carolina landscape, the transition between these secondary roads and the highway sections keeps the pace dynamic. You should be prepared for a drive that demands consistent engagement with the steering wheel rather than one that allows for long periods of highway cruising.
Only 21% highway — the rest is turn-by-turn surface driving.
19 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 17.4 mi on US Highway 521.
How Hard Is This Drive?
3/10
Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. There are only a few real navigation decisions along the way. The trickiest moment comes around 42.2 miles in near SC 261 / East Main Street.
Driving Effort3/10
Easy - simple navigation with a manageable amount of wheel time
Balances navigation complexity with total wheel time.
This is a straightforward 1h 56m drive. You will face about 10 decision points, but nothing that requires special attention if you follow navigation.
Where does it get tricky?
The main spots that need attention: at 42.2 miles (SC 261 / East Main Street): Navigation decision point; at 44.3 miles (US 52 / North Williamsburg County Highway): Navigation decision point; at 81.1 miles: Lane positioning matters here.
Georgetown, known for being a historic seaport, is nestled between Myrtle Beach and Charleston in South Carolina. It was established in 1732, making it the state’s third oldest city, behind Charleston and Beaufort. The waterfront city is inhabited by many museums, shops, restaurants, and historic attractions. It is best seen by walking and boat tours.
Florence is a city in the Pee Dee Country Region of South Carolina. It was the site of the Florence Stockade, a Confederate POW camp, notably bad but still maybe not as bad as Andersonville, then a railroad hub, and nowadays a regional center for medical care and manufacturing, including as it sits at the terminus for I-20. Even though it got started rather late, in 1871, it's more or less the hub for northeastern South Carolina, aka Pee Dee Country.
The longest stretch is about 17.4 miles on US Highway 521. The full list of main roads is in the Roads section above.
Yes. At under 2 hours behind the wheel, this works well for families — plan one quick stop if you have younger kids.
The main spots that need attention: at 42.2 miles (SC 261 / East Main Street): Navigation decision point; at 44.3 miles (US 52 / North Williamsburg County Highway): Navigation decision point; at 81.1 miles: Lane positioning matters here.
Yes. A round trip is manageable in a single day if you plan a break at Florence, SC before heading back.
