Florissant, MO to Palmyra, MO is 116.3 miles and takes about 2h 26m via Avenue of the Saints, with a fuel budget near $18 and enough daylight to finish in a day. This drive stays within Missouri, connecting two points in the Midwest. Expect a route with a fair number of turns, making it more of a local exploration than a high-speed transit. It's a comfortable, single-day trip that won't eat up your whole schedule, perfect for a relaxed journey.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Midpoint
58.2 miles from Florissant, MO
A natural place for your longest stop of the day
, about 1h 13m into the drive
.
Main Roads
Road
Distance
Duration
Avenue of the Saints
78.6 mi
1h 32m
I 70
21.6 mi
26m
Rosemary Straub Davison Highway
3.7 mi
4m
Veterans Road
3.2 mi
5m
US 61 Business
2.2 mi
4m
Lindbergh Boulevard
1.7 mi
3m
MO W
1.7 mi
2m
Washington Street
1 mi
1m
Longest stretch:
Avenue of the Saints
— 78.6 mi, about 1h 32m
Turn-by-Turn Driving Directions
Step-by-step road directions between Florissant, MO and Palmyra, MO.
1
Start on North New Florissant Road
87 ft·5 sec·North New Florissant Road
2
Turn right onto Washington Street
1.0 mi·1 min·Washington Street
3
Turn left onto US 67
1.7 mi·3 min·Lindbergh Boulevard
4
Take the ramp
0.4 mi·46 sec
Use the right lane.
5
Merge onto I 270
3.7 mi·4 min·Rosemary Straub Davison Highway
Use the straight / slight right lanes.
6
Take the exit
0.3 mi·25 sec
Exit 20AToward I 70: Saint Louis, Kansas City
7
Continue on this road
0.5 mi·42 sec·this road
Exit 20A-BToward I 70: Saint Louis, Kansas CityUse the slight left / slight right lanes.
8
Keep slight right at fork
0.5 mi·41 sec
Exit 20BToward I 70 West: Kansas CityUse the slight right lane.
9
Merge onto I 70
22 mi·26 min·I 70
Use the straight / slight right lanes.
10
Take the exit
0.4 mi·47 sec
Exit 210BToward US 61 North: HannibalUse the slight right lane.
11
Merge onto US 61
73 mi·1 hr 26 min·Avenue of the Saints
Use the right lane.
12
Take the exit
249 ft·14 sec
13
Turn left onto Paris Gravel Road
0.5 mi·1 min·Paris Gravel Road
14
Keep slight right at fork onto County Road 422
279 ft·8 sec·County Road 422
15
Turn right onto Veterans Road
3.2 mi·5 min·Veterans Road
16
Turn left onto MO W
1.7 mi·2 min·MO W
17
Turn left onto US 61
5.3 mi·6 min·Avenue of the Saints
18
Take the exit onto US 61 Business
2.2 mi·4 min·US 61 Business
19
Arrive at destination
US 61 Business
Trip Plan
Given the relatively short 2h 26m duration, you have flexibility with your departure time. Leaving in the morning allows ample time for any unexpected stops or to simply enjoy the drive without rushing. With only 116.3 miles, planning for a specific fuel stop might not be necessary, but keep an eye on your gauge, especially before heading onto the longest 78.6-mile stretch on Avenue of the Saints. This route's 'Turn-heavy local drive' nature means paying close attention to navigation is key.
Morning Departure
Leave by 9 AM and you'll arrive before lunch.
Evening Departure
Even a 4 PM departure gets you there before dark in summer.
You can normally do this drive in one day.
You may only need one short stretch break if traffic stays light.
The halfway point lands around 58.2 miles from Florissant, MO, or about 1h 13m into the drive.
The longest continuous stretch on this route runs about 78.6 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 26 miles or 34m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 58.2 miles or 1h 13m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 1h 57m
Traffic, exits, and arrival timing usually matter more near Palmyra, MO than in the middle of the route.
Before You Leave
+
Open the route before leaving Florissant, MO so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Florissant, MO
This is one driving day of about 116.3 miles and 2h 26m.
Your first comfortable stop window is around 26 miles from Florissant, MO.
This route can stay practical as a one-day drive if traffic stays reasonable.
The longest stretch is on Avenue of the Saints for about 78.6 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 15
5 decision points cluster between mile 3.1 and 29.7 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
5
3.1 mi into trip|~6m in|I 270 / Rosemary Straub Davison Highway
Merge onto I 270 / Rosemary Straub Davison Highway
Merge point - match speed before joining. Lane positioning matters here
Use the straight / slight right lanes.
6
6.9 mi into trip|~10m in
Take the exit toward I 70: Saint Louis, Kansas City
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Exit 20A
Toward I 70: Saint Louis, Kansas City
5
7.1 mi into trip|~11m in
Continue toward I 70: Saint Louis, Kansas City
Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight left / slight right lanes.
Exit 20A-B
Toward I 70: Saint Louis, Kansas City
8
7.6 mi into trip|~12m in
Keep slight right at fork toward I 70 West: Kansas City
Highway fork - watch signs carefully. Lane positioning matters here
Use the slight right lane.
Exit 20B
Toward I 70 West: Kansas City
7
29.7 mi into trip|~39m in
Take the exit toward US 61 North: Hannibal
Exit ramp - move to the correct lane early. Lane positioning matters here
Use the slight right lane.
Exit 210B
Toward US 61 North: Hannibal
Fuel & Cost
Regular Gas
$18.18 one way
$36.36 round trip
$3.97/gal25.4 MPG avg41 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.36
$19.96
$39.93
premium
$4.89
$22.38
$44.76
diesel
$5.61
$25.68
$51.36
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$18
Meals
$25–$50
Total
$43–$68
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 40.7 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $12 in charging
· 0 stops
· 66% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
34.9
0
$12.21
$5.58
Efficient EV
29.1
0
$10.18
$4.65
EV Truck/SUV
46.5
0
$16.28
$7.44
Gas CO2
41 kg
EV CO2
14 kg (66% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 20, 2026
Origin
Florissant, MO
Late night
in Florissant on Tuesday
Local time
5:58 AM
CDT
Current temp
72°F
Unavailable
Live forecast
Destination
Palmyra, MO
Late night
in Palmyra on Tuesday
Local time
5:58 AM
CDT
Current temp
50°F
Unavailable
Live forecast
68°F
Troy, MO
58 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
22 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
2h 26m on the road
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
Gateway Arch National Park
National Park
Gateway Arch National Park commemorates President Jefferson’s vision of a continental nation, the individuals and cultural groups who helped shape its history, St. Louis’ role in westward expansion, a...
Park data from the National Park Service API. Alerts update every 2 hours.
More Details
What kind of drive is this?
This route offers a 'Turn-heavy local drive' profile, with only 20% of the journey on highways. You'll spend most of your time navigating local roads, interspersed with segments on the Avenue of the Saints and I-70. The longest uninterrupted stretch you'll encounter is 78.6 miles on the Avenue of the Saints, offering a good period of consistent travel before you transition back to more varied local roads. Be prepared for frequent changes in direction as you make your way north.
Only 20% highway — the rest is turn-by-turn surface driving.
19 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 78.6 mi on Avenue of the Saints.
How Hard Is This Drive?
9/10
Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 3.1 miles in near I 270 / Rosemary Straub Davison Highway.
Driving Effort9/10
High effort - long or complex enough to need steady focus all day
Balances navigation complexity with total wheel time.
This is a demanding drive. With 15 significant decision points across 116.3 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 3.1 miles (I 270 / Rosemary Straub Davison Highway): Merge point - match speed before joining. Lane positioning matters here; at 6.9 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 7.1 miles: Lane positioning matters here. Multiple destination signs - pick the right one.
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
On the drive from Florissant, MO to Palmyra, MO, road signs begin pointing toward Kansas City along the way.
Kansas City
6.9 mi in|~10m
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 2h 26m. Total distance: 116.3 miles.
Family Friendly
Moderate complexity with 0 natural rest stops along the way.
Solo Traveler
2h 26m drive, comfortable solo distance.
Scenic Drive
Mostly surface roads route profile with national parks nearby.
Frequently Asked Questions
The longest stretch is about 78.6 miles on Avenue of the Saints. The full list of main roads is in the Roads section above.
Yes — we found about 5 rest areas or service plazas within a short detour of the route (from OpenStreetMap). See the Rest Stops tab under Nearby Places for locations and mile markers. Plan to stretch, use the bathroom, and top off fluids every 2–3 hours on longer drives.
It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Palmyra, MO before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. There are 5 rest areas along the route for bathroom stops.
The main spots that need attention: at 3.1 miles (I 270 / Rosemary Straub Davison Highway): Merge point - match speed before joining. Lane positioning matters here; at 6.9 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 7.1 miles: Lane positioning matters here. Multiple destination signs - pick the right one.
Yes — Gateway Arch National Park. See the National Parks section for detour distances and tips on detours.
Yes. A round trip is manageable in a single day if you plan a break at Palmyra, MO before heading back.
