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Trip from Esther, MO to Saint Joseph, MO

Compiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Apr 19, 2026 · Editorial standards

Drive Time

6h 49m

Distance

356.4 mi

574 km

Drive Score

9/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$56

one way

EV Charging

Unknown

Best Time to Leave

Save up to 35 min
4 AM
6h 38m ★
6 AM
6h 50m
8 AM
7h 13m
10 AM
6h 58m
12 PM
6h 55m
3 PM
6h 59m
5 PM
7h 12m
8 PM
6h 43m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

Downtown Esther, MO, MO

Esther, MO

Lena Khrupina

city in and county seat of Buchanan County, Missouri, United States

Saint Joseph, MO

Wikimedia Commons

Trip Overview

Esther, MO to Saint Joseph, MO is 356.4 miles and takes about 6h 49m via the Dwight D Eisenhower Highway, with a fuel budget near $56 and enough daylight to finish in a day. This drive keeps you within the Midwest region, traversing Missouri for its entirety. It's a straightforward trip, mostly on one main highway, making it a solid option if you're looking for a direct route with minimal navigation. Consider this drive if you prefer a predictable journey with a clear destination in mind.

Trip Pace

Same-day drive is realistic

A same-day return is possible, but it will make for a full day on the road.

Break Rhythm

1 planned break

Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

Midpoint

178.2 miles from Esther, MO

A natural place for your longest stop of the day , about 3h 33m into the drive .

Main Roads

Road Distance Duration
Dwight D Eisenhower Highway 80.7 mi 1h 35m
U.S. Submarine Veterans' Memorial Highway 54.4 mi 58m
Dwight D. Eisenhower Highway 54.3 mi 58m
US 67 26.6 mi 30m
I 29 26 mi 27m
Avenue of the Saints 25.4 mi 30m
I 435 20.9 mi 22m
I 55 20.5 mi 22m
Longest stretch: Dwight D Eisenhower Highway — 80.7 mi, about 1h 35m

Turn-by-Turn Driving Directions

Step-by-step road directions between Esther, MO and Saint Joseph, MO.

1

Start on Jefferson Street

0.1 mi · 22 sec · Jefferson Street
2

At end of road, turn right onto Saint Joe Drive

1.4 mi · 2 min · Saint Joe Drive
3

Continue on South State Street

1.2 mi · 2 min · South State Street
4

Turn right onto US 67 Business; MO 8

0.1 mi · 18 sec · US 67 Business; MO 8
5

Take the ramp

0.2 mi · 21 sec
Toward US 67 North: Saint Louis
6

Merge onto US 67

26 mi · 30 min · US 67
7

Keep slight right at fork onto US 67

0.3 mi · 27 sec · US 67
8

Take the exit

0.3 mi · 49 sec
Toward I 55 North: Saint Louis
9

Merge onto I 55

21 mi · 22 min · I 55
10

Continue on I 55

1.3 mi · 1 min · Rosa Parks Highway
11

Take the exit

0.2 mi · 27 sec
Exit 196 Toward I 270 West, I 255 East: Kansas City, Chicago Use the slight right lane.
12

Keep slight left at fork

388 ft · 8 sec
Toward I 270 West: Kansas City Use the slight left lane.
13

Continue on this road

0.7 mi · 1 min · this road
Exit 196 Toward I 270 West
14

Merge onto I 270

11 mi · 14 min · I 270
Use the straight lane.
15

Take the exit

0.1 mi · 17 sec
Exit 12 Toward I 64, US 40, US 61: Wentzville, Saint Louis Use the slight right lane.
16

Keep slight left at fork

0.4 mi · 48 sec
Toward I 64 West, US 40 West, US 61 North: Wentzville Use the slight left lane.
17

Continue on this road

0.1 mi · 9 sec · this road
Exit 12 Toward I 64 West, US 40 West, US 61 North: Wentzville
18

Merge onto I 64; US 40; US 61

25 mi · 30 min · Avenue of the Saints
Use the straight lane.
19

Take the exit onto US 40

0.6 mi · 1 min · US 40
Exit 1A Toward I 70 West, US 40 West: Kansas City Use the straight / slight left lanes.
20

Merge onto I 70; US 40

81 mi · 1 hr 35 min · Dwight D Eisenhower Highway
21

Continue on I 70; US 40

2.0 mi · 2 min · Sheriff Roger I. Wilson Memorial Highway
22

Continue on I 70; US 40

1.6 mi · 1 min · Highway Patrol Sgt. Benjamin Booth Memorial Highway
23

Continue on I 70; US 40

1.8 mi · 2 min · Dwight D. Eisenhower Highway
24

Continue on I 70; US 40

54 mi · 58 min · U.S. Submarine Veterans' Memorial Highway
25

Continue on I 70; US 40

52 mi · 56 min · Dwight D. Eisenhower Highway
26

Continue on I 70

2.7 mi · 3 min · Truman/Eisenhower Presidential Highway
27

Continue on I 70

1.8 mi · 2 min · Clifton J. Scott Memorial Highway
Use the straight / slight right lanes.
28

Continue on I 70

2.9 mi · 3 min · Truman/Eisenhower Presidential Highway
29

Continue on I 70

0.8 mi · 58 sec · George Brett Super Highway
30

Take the exit

1.1 mi · 2 min
Exit 8B Toward I 435 North, US 24 East: Des Moines Use the straight / slight right lanes.
31

Merge onto I 435; US 24

7.8 mi · 9 min · Lamar Hunt Memorial Highway
32

Continue on I435 N

1.3 mi · 1 min · I435 N
33

Continue on I 435

21 mi · 22 min · I 435
34

Keep slight left at fork onto I 29; US 71

26 mi · 27 min · I 29; US 71
Toward I 29 North, US 71 North: Saint Joseph
35

Take the exit

0.5 mi · 54 sec
Exit 43 Toward I 229 North: Downtown Saint Joseph
36

Continue on I 229

5.7 mi · 6 min · I 229
37

Take the exit

0.3 mi · 33 sec
Exit 6A Toward Central Business District
38

Continue on Edmond Street

0.5 mi · 57 sec · Edmond Street
39

Turn left onto I 29 Business

0.2 mi · 20 sec · South 10th Street
40

Turn right onto I 29 Business

379 ft · 6 sec · Frederick Avenue
41

Turn slight right onto Walter Welsh Avenue

137 ft · 2 sec · Walter Welsh Avenue
42

Arrive at destination

Walter Welsh Avenue

Trip Plan

To make the most of this 6 hour and 49 minute drive, consider departing in the morning to ensure you have ample daylight. With only one recommended stop, you can plan for a brief break midway, perhaps around the 3-4 hour mark, to refuel and stretch. The $56 fuel cost is an estimate, so keep an eye on your gauge, especially during longer stretches like the 80.7 miles on the Dwight D. Eisenhower Highway. Since this is a single-day trip, you have flexibility; however, planning around the main highway sections will help maintain momentum.

Morning Departure

Start early — leave by 6-7 AM to arrive at a reasonable hour.

Evening Departure

This is a long drive — plan for a morning departure or consider splitting it into two days.

You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 178.2 miles from Esther, MO, or about 3h 33m into the drive.
The longest continuous stretch on this route runs about 80.7 miles.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 78 miles or 1h 34m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 178.2 miles or 3h 33m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 5h 42m

Traffic, exits, and arrival timing usually matter more near Saint Joseph, MO than in the middle of the route.

Before You Leave

+

Open the route before leaving Esther, MO so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from Esther, MO

This is one driving day of about 356.4 miles and 6h 49m.

Your first comfortable stop window is around 78 miles from Esther, MO.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on Dwight D Eisenhower Highway for about 80.7 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

city in St. Charles County, Missouri, United States

Mid-route town

Meal stop

Wentzville, MO

178 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

Chesterfield, MO

Fuel and coffee

A short stop after about 78 miles helps settle the day before fatigue starts building.

Columbia, MO

Meal break

The midpoint is around 178.2 miles from Esther, MO, which is a good place for a longer meal and fuel stop.

Before the longest stretch

Fuel check

Top up before Dwight D Eisenhower Highway if your tank is already low. That segment runs about 80.7 miles.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Heads-up: tricky spots

5 of 23

5 decision points cluster between mile 51.8 and 90.4 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.

8
51.8 mi into trip | ~1h 1m in

Take the exit toward I 270 West, I 255 East: Kansas City, Chicago

Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one

Use the slight right lane. Exit 196 Toward I 270 West, I 255 East: Kansas City, Chi...
8
52 mi into trip | ~1h 1m in

Keep slight left at fork toward I 270 West: Kansas City

Highway fork - watch signs carefully. Lane positioning matters here

Use the slight left lane. Toward I 270 West: Kansas City
8
64.3 mi into trip | ~1h 17m in

Take the exit toward I 64, US 40, US 61: Wentzville, Saint Louis

Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one

Use the slight right lane. Exit 12 Toward I 64, US 40, US 61: Wentzville, Saint Lo...
8
64.5 mi into trip | ~1h 17m in

Keep slight left at fork toward I 64 West, US 40 West, US 61 North: Wentzville

Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one

Use the slight left lane. Toward I 64 West, US 40 West, US 61 North: Went...
8
90.4 mi into trip | ~1h 49m in | US 40

Take the exit onto US 40 toward I 70 West, US 40 West: Kansas City

Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one

Use the straight / slight left lanes. Exit 1A Toward I 70 West, US 40 West: Kansas City

Fuel & Cost

Regular Gas

$55.72 one way

$111.44 round trip

$3.97/gal 25.4 MPG avg 125 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.36 $61.18 $122.35
premium $4.89 $68.59 $137.17
diesel $5.61 $78.69 $157.38

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$56

Meals

$25–$50

Total

$81–$106

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 124.7 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $37 in charging · 1 stop · 66% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 106.9 1 $37.42 $17.11
Efficient EV 89.1 1 $31.18 $14.26
EV Truck/SUV 142.6 1 $49.90 $22.81

Gas CO2

125 kg

EV CO2

42 kg (66% less)

Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Apr 18, 2026

Origin

Esther, MO

Evening in Esther on Saturday

Local time

8:08 PM

CDT

Current temp

82°F

Unavailable

Live forecast

Destination

Saint Joseph, MO

Evening in Saint Joseph on Saturday

Local time

8:08 PM

CDT

Current temp

60°F

Sunny

NW 12 to 15 mph 3% chance Live forecast

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

22 degrees cooler at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

6h 49m on the road

Start early — leave by 6-7 AM to arrive at a reasonable hour.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

National Parks Near This Route

Worth a detour if your schedule allows.

Gateway Arch National Park

Gateway Arch National Park

National Park

Gateway Arch National Park commemorates President Jefferson’s vision of a continental nation, the individuals and cultural groups who helped shape its history, St. Louis’ role in westward expansion, a...

14 mi from route ~36 min detour $19 near mile 61.4
View on nps.gov
Ste. Geneviève National Historical Park

Ste. Geneviève National Historical Park

National Historical Park

Established by 1750, Ste. Geneviève was the first permanent European settlement in Missouri. Early French Canadian settlers were drawn here by the rich agricultural land known as Le Grand Champ (the B...

26 mi from route ~64 min detour Free near mile 24.6
View on nps.gov

Park data from the National Park Service API. Alerts update every 2 hours.

What kind of drive is this?

This route offers a mixed drive experience, with 32% of the journey on major highways like the Dwight D. Eisenhower Highway and the U.S. Submarine Veterans' Memorial Highway. You'll encounter an 80.7-mile stretch on the Dwight D. Eisenhower Highway, offering a longer, uninterrupted segment. While much of the drive utilizes these primary routes, expect some variation as you transition between them. The overall character is one of steady progress, suitable for those who appreciate a consistent pace on the road.

32% highway, the rest on surface roads — varied driving throughout.
42 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 80.7 mi on Dwight D Eisenhower Highway.

How Hard Is This Drive?

10/10

This route mixes highway mileage with some local-road sections near the start or finish. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 51.8 miles in.

Driving Effort 10/10

High effort - long or complex enough to need steady focus all day

Balances navigation complexity with total wheel time.

This is a demanding drive. With 23 significant decision points across 356.4 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.

Where does it get tricky?

The main spots that need attention: at 51.8 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 52 miles: Highway fork - watch signs carefully. Lane positioning matters here; at 64.3 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.

Towns Mentioned on Route Signs

Based on OSRM destination-sign hints, not a full list of every settlement the road passes.

Between Esther, MO and Saint Joseph, MO, road signs point toward Chicago and Saint Louis.

Chicago

51.8 mi in | ~1h 1m

Saint Louis

64.3 mi in | ~1h 17m

Who Is This Route For?

Weekend Trip

Doable as a same-day drive at 6h 49m. Total distance: 356.4 miles.

Family Friendly

Moderate complexity with 1 natural rest stops along the way.

Solo Traveler

6h 49m drive, plan rest stops for pacing.

Scenic Drive

Mixed highway & surface route profile with national parks nearby.

Frequently Asked Questions

The longest stretch is about 80.7 miles on Dwight D Eisenhower Highway. The full list of main roads is in the Roads section above.

We did not find dedicated rest areas on this route. For a drive this long, plan bathroom and stretch breaks around gas stations, fast-food stops, or small-town downtowns — check the Nearby Places section for options.

It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Saint Joseph, MO before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.

Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. Dedicated rest areas are limited, so plan gas or food stops as your bathroom breaks.

The main spots that need attention: at 51.8 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 52 miles: Highway fork - watch signs carefully. Lane positioning matters here; at 64.3 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.

Yes — Gateway Arch National Park and Ste. Geneviève National Historical Park. See the National Parks section for detour distances and tips on detours.

Not recommended in a single day. At 6.8 hours each way, a round trip means 13.7 hours of driving — that is an unsafe level of fatigue for most drivers. Plan at least one night at Saint Joseph, MO before the return drive.

How this page is built

Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, and NPS for national parks. See our methodology for refresh cadence and limitations.

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