D'Iberville to Tupelo is 305 miles and takes about 5 hours 54 minutes via Lance Corporal Roy M Wheat Memorial Highway and US 45, with a fuel budget near $48 and enough daylight to finish in a day. This trip primarily travels through Mississippi, moving from the Southeast region towards the northern part of the state. The route offers a straightforward drive that's mostly on highways, making it a convenient option for a single-day trip. It’s a practical choice if you're looking to cover ground efficiently between these two Mississippi locations.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
152.6 miles from D'Iberville, MS
A natural place for your longest stop of the day
, about 2h 54m into the drive
.
Main Roads
Road
Distance
Duration
Lance Corporal Roy M Wheat Memorial Highway
88.4 mi
1h 35m
US 45
65.1 mi
1h 14m
US Highway 45 Alternate
53 mi
1h 3m
US 49
42.2 mi
49m
MS 15
20.7 mi
24m
Martin Luther King Drive
18.1 mi
20m
I 59
9 mi
10m
US 98
3.3 mi
4m
Longest stretch:
Lance Corporal Roy M Wheat Memorial Highway
— 88.4 mi, about 1h 35m
Traffic on I-59
Hour-of-day weekday pattern from 12 FHWA count stations on your route.
Peak
4 PM
~976 veh/hr typical
· worst 1,182
Quietest
2 AM
~88 veh/hr
Peak-to-quiet ratio
11.1×
busier at peak than in the quiet hours
12a6anoon6p11p
Averaged across 52 weeks of 2023 FHWA Travel Monitoring Analysis System data. Weekday hours only (Mon–Fri).
Turn-by-Turn Driving Directions
Step-by-step road directions between D'Iberville, MS and Tupelo, MS.
1
Start on Race Track Road
63 ft·3 sec·Race Track Road
2
Turn right onto Central Avenue
0.2 mi·37 sec·Central Avenue
3
Turn left onto Rodriguez Street
0.1 mi·22 sec·Rodriguez Street
4
Take the ramp
0.3 mi·37 sec
5
Merge onto I 110
1.3 mi·1 min·I 110
6
Continue on MS 15; MS 67
21 mi·24 min·MS 15; MS 67
Use the straight lane.
7
Keep slight right at fork
0.4 mi·47 sec
Toward US 49 North: Hattiesburg, Jackson
8
Merge onto US 49
40 mi·46 min·US 49
Use the straight lane.
9
Continue on US 49
2.4 mi·2 min·US 49
Use the straight / slight right lanes.
10
Take the exit
0.3 mi·51 sec
11
Merge onto US 98
2.5 mi·2 min·US 98
Use the straight / slight right lanes.
12
Take the exit onto US 98
0.8 mi·1 min·US 98
Toward I 59 North, US 98 West: Columbia, LaurelUse the straight / slight right lanes.
13
Merge onto I 59; US 98
88 mi·1 hr 35 min·Lance Corporal Roy M Wheat Memorial Highway
Use the straight / slight right lanes.
14
Keep slight right at fork onto I 59
9.0 mi·10 min·I 59
Toward I 59 North, I 20 East: Meridian, TuscaloosaUse the straight lane.
15
Take the exit
0.3 mi·47 sec
Toward US 45 North: MaconUse the slight right lane.
16
Merge onto US 45
65 mi·1 hr 14 min·US 45
Use the straight lane.
17
Keep slight left at fork onto US 45 ALT
53 mi·1 hr 3 min·US Highway 45 Alternate
Toward US 45 Alternate North: West Point, TupeloUse the straight / slight left lanes.
18
Continue on US 45 ALT
18 mi·20 min·Martin Luther King Drive
19
Continue on US 45; MS 6
1.5 mi·2 min·Martin Luther King, Junior Drive
20
Take the exit onto MS 6
0.4 mi·49 sec·MS 6
Toward MS 6 East: Downtown Tupelo
21
Keep slight left at fork
170 ft·7 sec
22
Turn left onto MS 6
0.7 mi·1 min·East Main Street
Use the straight lane.
23
Turn right onto North Spring Street
230 ft·10 sec·North Spring Street
24
Arrive at destination
North Spring Street
Trip Plan
Given the 5 hour 54 minute estimated drive time, starting in the morning from D'Iberville should allow you to reach Tupelo with plenty of daylight. With only one recommended stop, you have flexibility in pacing your drive. Keep an eye on your fuel gauge, especially during the 88.4-mile stretch on Lance Corporal Roy M Wheat Memorial Highway, as services might be less frequent. The $48 fuel cost is an estimate, so checking current prices is always a good idea before you depart.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 152.6 miles from D'Iberville, MS, or about 2h 54m into the drive.
The longest continuous stretch on this route runs about 88.4 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 67 miles or 1h 20m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 152.6 miles or 2h 54m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 4h 47m
Traffic, exits, and arrival timing usually matter more near Tupelo, MS than in the middle of the route.
Before You Leave
+
Open the route before leaving D'Iberville, MS so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from D'Iberville, MS
This is one driving day of about 305.2 miles and 5h 54m.
Your first comfortable stop window is around 67 miles from D'Iberville, MS.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on Lance Corporal Roy M Wheat Memorial Highway for about 88.4 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 18
5 decision points cluster between mile 22.6 and 231.5 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
6
22.6 mi into trip|~27m in
Keep slight right at fork toward US 49 North: Hattiesburg, Jackson
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Toward US 49 North: Hattiesburg, Jackson
7
68 mi into trip|~1h 21m in|US 98
Take the exit onto US 98 toward I 59 North, US 98 West: Columbia, Laurel
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / slight right lanes.
Toward I 59 North, US 98 West: Columbia, Laurel
8
157.2 mi into trip|~2h 59m in|I 59
Keep slight right at fork onto I 59 toward I 59 North, I 20 East: Meridian, Tuscaloosa
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight lane.
Toward I 59 North, I 20 East: Meridian, Tuscalo...
6
166.2 mi into trip|~3h 9m in
Take the exit toward US 45 North: Macon
Exit ramp - move to the correct lane early. Lane positioning matters here
Use the slight right lane.
Toward US 45 North: Macon
8
231.5 mi into trip|~4h 24m in|US 45 ALT / US Highway 45 Alternate
Keep slight left at fork onto US 45 ALT / US Highway 45 Alternate toward US 45 Alternate North: West Point, Tupelo
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / slight left lanes.
Toward US 45 Alternate North: West Point, Tupel...
Fuel & Cost
Regular Gas
$42.37 one way
$84.74 round trip
$3.53/gal25.4 MPG avg107 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$3.95
$47.40
$94.80
premium
$4.29
$51.54
$103.07
diesel
$4.80
$57.63
$115.26
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$42
Meals
$25–$50
Total
$67–$92
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 106.8 kg one way.
Prices: EIA weekly data, 2026-07-13.
Driving Electric?
About $32 in charging
· 1 stop
· 66% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
91.6
1
$32.05
$14.65
Efficient EV
76.3
0
$26.71
$12.21
EV Truck/SUV
122.1
1
$42.73
$19.53
Gas CO2
107 kg
EV CO2
36 kg (66% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Jul 17, 2026
Origin
D'Iberville, MS
Late night
in D'Iberville on Sunday
Local time
2:13 AM
CDT
Current temp
97°F
Mostly Sunny
W 5 to 10 mph4% chanceLive forecast
Destination
Tupelo, MS
Late night
in Tupelo on Sunday
Local time
2:13 AM
CDT
Current temp
95°F
Slight Chance Showers And Thunderstorms
WNW 10 mph15% chanceLive forecast
93°F
Meridian, MS
153 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
2 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
5h 54m on the road
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
Tupelo National Battlefield
National Battlefield
In July, 1864, federal forces, including men from the United States Colored Troops, marched into Tupelo, Mississippi. Disorganized Confederate soldiers fought fiercely but could not overpower the fede...
2 mi from route
~5 min detour
Free
near mile 305.2
The Natchez Trace National Scenic Trail is five sections of hiking trail running roughly parallel to the 444-mile long Natchez Trace Parkway scenic motor road. The foot trails total more than 60 miles...
5 mi from route
~12 min detour
Free
near mile 305.2
Park data from the National Park Service API. Alerts update every 2 hours.
More Details
What kind of drive is this?
You'll spend about 64% of this trip on highways, with the longest continuous stretch covering 88.4 miles on Lance Corporal Roy M Wheat Memorial Highway. After the highway segments, you'll transition to US 45 and US Highway 45 Alternate, which will offer a different driving experience with potentially more local traffic and varied speed limits. Expect a mix of cruising and more engaged driving as you navigate between these road types.
64% highway — fuel and pacing are the main things to plan.
24 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 88.4 mi on Lance Corporal Roy M Wheat Memorial Highway.
How Hard Is This Drive?
10/10
This is a straightforward highway drive that stays mostly on Lance Corporal Roy M Wheat Memorial Highway and US 45. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 22.6 miles in.
Driving Effort10/10
High effort - long or complex enough to need steady focus all day
Balances navigation complexity with total wheel time.
This is a demanding drive. With 18 significant decision points across 305.2 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 22.6 miles: Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 68 miles (US 98): Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 157.2 miles (I 59): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one.
Elevation Profile
Mostly flat terrain
480 ft14 ft
Total Climb
721 ft
Total Descent
458 ft
Highest Point
480 ft
~152.6 mi in
Elevation Range
466 ft
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between D'Iberville, MS and Tupelo, MS, road signs point toward Jackson, Laurel and Tuscaloosa.
Doable as a same-day drive at 5h 54m. Total distance: 305.2 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
5h 54m drive, comfortable solo distance.
Frequently Asked Questions
The longest stretch is about 88.4 miles on Lance Corporal Roy M Wheat Memorial Highway. The full list of main roads is in the Roads section above.
Yes — we found about 9 rest areas or service plazas within a short detour of the route (from OpenStreetMap). See the Rest Stops tab under Nearby Places for locations and mile markers. Plan to stretch, use the bathroom, and top off fluids every 2–3 hours on longer drives.
It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Tupelo, MS before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. There are 9 rest areas along the route for bathroom stops.
The main spots that need attention: at 22.6 miles: Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 68 miles (US 98): Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 157.2 miles (I 59): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one.
Yes — Tupelo National Battlefield and Natchez Trace National Scenic Trail. See the National Parks section for detour distances and tips on detours.
Not recommended in a single day. At 5.9 hours each way, a round trip means 11.8 hours of driving — that is an unsafe level of fatigue for most drivers. Plan at least one night at Tupelo, MS before the return drive.
