Anderson County Airport, SC to Pamplico, SC is 218.2 miles and takes about 4h 32m via I 20 and I 26, with a fuel budget near $36 and enough daylight to finish in a day. This trip stays within the Southeast region, primarily traversing South Carolina. Expect a largely highway-based experience, making it a straightforward drive. With only one recommended stop and a duration under five hours, it's well-suited for a single-day excursion, allowing for flexibility in your schedule.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
109.1 miles from Anderson County Airport, SC
A natural place for your longest stop of the day
, about 2h 15m into the drive
.
Main Roads
Road
Distance
Duration
I 20
79.3 mi
1h 29m
I 26
55.2 mi
1h
Golden Strip Freeway
22.9 mi
24m
Pamplico Highway
17.4 mi
30m
Highway 418
9.9 mi
14m
Cooley Bridge Road
5.6 mi
8m
Belton Highway
4.7 mi
6m
2nd Loop Road
3.6 mi
6m
Longest stretch:
I 20
— 79.3 mi, about 1h 29m
Traffic on I-20
Hour-of-day weekday pattern from 34 FHWA count stations on your route.
Peak
4 PM
~2,146 veh/hr typical
· worst 2,576
Quietest
2 AM
~168 veh/hr
Peak-to-quiet ratio
12.8×
busier at peak than in the quiet hours
12a6anoon6p11p
Averaged across 52 weeks of 2023 FHWA Travel Monitoring Analysis System data. Weekday hours only (Mon–Fri).
Turn-by-Turn Driving Directions
Step-by-step road directions between Anderson County Airport, SC and Pamplico, SC.
1
Start on this road
293 ft·21 sec·this road
2
Turn right onto Airport Road
0.7 mi·1 min·Airport Road
3
Turn right onto SC 24
0.7 mi·1 min·Highway 24
4
Continue on SC 24
1.0 mi·1 min·West Whitner Street
5
Turn right onto SC 28
2.2 mi·2 min·Highway 28 Bypass
6
Continue on SC 28
0.5 mi·33 sec·Pearman Dairy Road
7
Turn left onto US 29
0.1 mi·20 sec·South Murray Avenue
8
Turn right onto US 29
2.0 mi·2 min·West Shockley Ferry Road
9
Turn right onto US 29; US 76; US 178
2.6 mi·3 min·East River Street
10
Continue on US 76; US 178
4.7 mi·6 min·Belton Highway
11
Continue on US 76; US 178
2.3 mi·3 min·Anderson Street
12
Turn left onto SC 20
374 ft·14 sec·North Main Street
13
Turn right onto SC 247
1.3 mi·2 min·River Street
14
Continue on SC 247
3.6 mi·4 min·Highway 247
15
Continue on SC 247
5.6 mi·8 min·Cooley Bridge Road
16
At end of road, turn left onto US 25
0.1 mi·13 sec·Augusta Road
17
Turn right onto SC 418
9.9 mi·14 min·Highway 418
18
Continue on SC 418
1.3 mi·2 min·Milacron Drive
19
Continue on SC 418
0.2 mi·19 sec·McCarter Road
20
Take the ramp
0.3 mi·42 sec
21
Merge onto I 385
23 mi·24 min·Golden Strip Freeway
Use the slight right lane.
22
Merge onto I 26
55 mi·1 hr·I 26
Use the slight right lane.
23
Take the exit
0.3 mi·41 sec
Exit 107BToward I 20 East: FlorenceUse the right lane.
24
Merge onto I 20
79 mi·1 hr 29 min·I 20
Use the straight / slight right lanes.
25
Turn sharp right onto S-21-31
0.2 mi·25 sec·West Evans Street
26
Continue on SC 51
3.6 mi·6 min·2nd Loop Road
27
Continue on SC 51
17 mi·30 min·Pamplico Highway
28
Turn left onto East Main Street
31 ft·8 sec·East Main Street
29
Turn left onto State Road S-21-132
67 ft·3 sec·North Walnut Street
30
Arrive at destination
State Road S-21-132
Trip Plan
To make the most of this 218.2-mile drive, consider departing early in the morning to avoid potential traffic, especially as you get closer to your destination. The total duration of about 4 hours and 32 minutes means you can comfortably complete this in one day, so you have flexibility with stops. Plan for one primary stop to refuel and stretch your legs, as the longest stretch between exits is nearly 80 miles. Keep an eye on your fuel gauge, particularly before embarking on the 79.3-mile segment on I 20, to ensure you have enough to reach your destination or a convenient service area.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 109.1 miles from Anderson County Airport, SC, or about 2h 15m into the drive.
The longest continuous stretch on this route runs about 79.3 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 48 miles or 1h 8m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 109.1 miles or 2h 15m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 34m
Traffic, exits, and arrival timing usually matter more near Pamplico, SC than in the middle of the route.
Before You Leave
+
Open the route before leaving Anderson County Airport, SC so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Anderson County Airport, SC
This is one driving day of about 218.2 miles and 4h 32m.
Your first comfortable stop window is around 48 miles from Anderson County Airport, SC.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on I 20 for about 79.3 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 16
5 decision points cluster between mile 39.3 and 218.2 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
5
39.3 mi into trip|~59m in|I 385 / Golden Strip Freeway
Merge onto I 385 / Golden Strip Freeway
Merge point - match speed before joining. Lane positioning matters here
Use the slight right lane.
5
62.2 mi into trip|~1h 23m in|I 26
Merge onto I 26
Merge point - match speed before joining. Lane positioning matters here
Use the slight right lane.
7
117.3 mi into trip|~2h 24m in
Take the exit toward I 20 East: Florence
Exit ramp - move to the correct lane early. Lane positioning matters here
Use the right lane.
Exit 107B
Toward I 20 East: Florence
5
117.7 mi into trip|~2h 24m in|I 20
Merge onto I 20
Merge point - match speed before joining. Lane positioning matters here
Use the straight / slight right lanes.
5
218.2 mi into trip|~4h 32m in|State Road S-21-132 / North Walnut Street
Turn left onto State Road S-21-132 / North Walnut Street
Navigation decision point
Fuel & Cost
Regular Gas
$34.71 one way
$69.41 round trip
$4.04/gal25.4 MPG avg76 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.41
$37.84
$75.68
premium
$4.78
$41.05
$82.11
diesel
$5.35
$45.96
$91.92
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$35
Meals
$25–$50
Total
$60–$85
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 76.3 kg one way.
Prices: EIA weekly data, 2026-06-01.
Driving Electric?
About $23 in charging
· 0 stops
· 66% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
65.5
0
$22.91
$10.47
Efficient EV
54.6
0
$19.09
$8.73
EV Truck/SUV
87.3
1
$30.55
$13.96
Gas CO2
76 kg
EV CO2
26 kg (66% less)
Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Jun 1, 2026
Origin
Anderson County Airport, SC
Afternoon
in Anderson County Airport on Wednesday
Local time
3:02 PM
EDT
Current temp
63°F
Chance Rain Showers
0 mph29% chanceLive forecast
Destination
Pamplico, SC
Afternoon
in Pamplico on Wednesday
Local time
3:02 PM
EDT
Current temp
64°F
Chance Showers And Thunderstorms
NE 1 mph52% chanceLive forecast
67°F
Rock Hill, SC
109 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
1 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
4h 32m on the road
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
Congaree National Park
National Park
Astonishing biodiversity exists in Congaree National Park, the largest intact expanse of old growth bottomland hardwood forest remaining in the southeastern United States. Waters from the Congaree and...
22 mi from route
~55 min detour
Free
near mile 135.4
Park data from the National Park Service API. Alerts update every 2 hours.
More Details
What kind of drive is this?
This route is mostly highway, with 80% of the drive on major interstates. You'll encounter your longest stretch on I 20, covering 79.3 miles without needing to exit. The transition to surface roads will occur after significant highway mileage. Expect a relatively consistent driving experience, with the potential for frequent exits and merging traffic as you navigate between interstates.
80% highway — fuel and pacing are the main things to plan.
30 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 79.3 mi on I 20.
How Hard Is This Drive?
4/10
This is a straightforward highway drive that stays mostly on I 20 and I 26. There are only a few real navigation decisions along the way. The trickiest moment comes around 39.3 miles in near I 385 / Golden Strip Freeway.
Driving Effort4/10
Easy - simple navigation with a manageable amount of wheel time
Balances navigation complexity with total wheel time.
This is a straightforward 4h 32m drive. You will face about 16 decision points, but nothing that requires special attention if you follow navigation.
Where does it get tricky?
The main spots that need attention: at 39.3 miles (I 385 / Golden Strip Freeway): Merge point - match speed before joining. Lane positioning matters here; at 62.2 miles (I 26): Merge point - match speed before joining. Lane positioning matters here; at 117.3 miles: Exit ramp - move to the correct lane early. Lane positioning matters here.
The longest stretch is about 79.3 miles on I 20. The full list of main roads is in the Roads section above.
Yes — we found about 15 rest areas or service plazas within a short detour of the route (from OpenStreetMap). See the Rest Stops tab under Nearby Places for locations and mile markers. Plan to stretch, use the bathroom, and top off fluids every 2–3 hours on longer drives.
Yes, with realistic expectations. Build in a stop roughly every 2 hours, have snacks and activities ready, and check the Nearby Places tabs for kid-friendly stops along the way.
The main spots that need attention: at 39.3 miles (I 385 / Golden Strip Freeway): Merge point - match speed before joining. Lane positioning matters here; at 62.2 miles (I 26): Merge point - match speed before joining. Lane positioning matters here; at 117.3 miles: Exit ramp - move to the correct lane early. Lane positioning matters here.
Yes — Congaree National Park. See the National Parks section for detour distances and tips on detours.
Possible but tiring. At 4.5 hours each way, an in-and-out day trip would put you behind the wheel for 9.1 hours — manageable with a long break at Pamplico, SC, but most travelers stay overnight.
