Rainforest Cafe
Near the start, ~10 min detour
Tempe, Arizona
Hours: 11 am–9 pm
+14807529100
Visit websiteCompiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Jul 19, 2026 · Editorial standards
Drive Time
4h 4m
Distance
220.2 mi
354 km
Drive Score
9/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$39
one way
EV Charging
Unknown
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Tempe, AZ
Wikimedia Commons
San Luis, AZ
Wikimedia Commons
Tempe, AZ to San Luis, AZ is 220.2 miles and takes about 4h 4m via Blue Star Memorial Highway, Phoenix Bypass Route, and Robert A. Vaughan Expressway, with a fuel budget near $46 and enough daylight to finish in a day. This trip stays within Arizona, traversing the Desert Southwest region for its entirety. Expect a drive that's mostly on surface roads, offering a more grounded perspective of the landscape. It's a straightforward, single-day option if you're looking for an efficient way to get from point A to point B without extensive highway cruising.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
110.1 miles from Tempe, AZ
A natural place for your longest stop of the day , about 2h 5m into the drive .
| Road | Distance | Duration |
|---|---|---|
| Blue Star Memorial Highway | 111.9 mi | 1h 54m |
| Phoenix Bypass Route | 31.6 mi | 31m |
| Robert A. Vaughan Expressway | 20.9 mi | 24m |
| North John Wayne Parkway | 14.8 mi | 18m |
| North Maricopa Road | 11.8 mi | 13m |
| Maricopa Freeway | 6.1 mi | 7m |
| Gila Bend–Casa Grande Highway | 5.6 mi | 6m |
| East Cesar Chavez Boulevard | 4.5 mi | 7m |
Step-by-step road directions between Tempe, AZ and San Luis, AZ.
Start on US 80 Hist
Continue on US 80 Hist
Turn right onto South McClintock Drive
Take the ramp
Merge onto US 60
Take the exit
Keep slight left at fork
Merge onto I 10
Continue on I 10
Take the exit
Turn right onto AZ 347
Continue on AZ 347
Continue on AZ 347
At end of road, turn right onto AZ 84
Take the exit
Merge onto I 8
Continue on I 8
Take the exit
Keep slight left at fork
Enter roundabout onto AZ 195
Continue on AZ 195
Enter roundabout onto AZ 195
Continue on AZ 195
Continue on AZ 195
Continue on AZ 195
Turn left onto 4th Avenue
At end of road, turn right onto Urtuzuastegui Street
Arrive at destination
Given the 4h 4m estimated drive time, starting in the morning from Tempe is ideal to maximize daylight. With only one recommended stop and a short overall duration, you have flexibility in pacing yourself. Keep an eye on your fuel, especially since the estimated cost is $46 for the 220.2 miles. Since much of this route involves surface roads, be aware of potential local traffic and speed limit changes. The longest uninterrupted stretch is over 111 miles, so plan your fuel and rest stops accordingly before you hit that segment.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 48 miles or 1h 1m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 110.1 miles or 2h 5m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 17m
Traffic, exits, and arrival timing usually matter more near San Luis, AZ than in the middle of the route.
Open the route before leaving Tempe, AZ so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Tempe, AZ
This is one driving day of about 220.2 miles and 4h 4m.
Rest stops, refuel points, and overnight suggestions along this route.
Mid-route town
Meal stop
110 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 48 miles helps settle the day before fatigue starts building.
The midpoint is around 110.1 miles from Tempe, AZ, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before Blue Star Memorial Highway if your tank is already low. That segment runs about 111.9 miles.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Picked by where they fit in your drive — first break, midpoint reset, final stretch.
Near the start, ~10 min detour
Tempe, Arizona
Hours: 11 am–9 pm
+14807529100
Visit websiteNear the start, short detour
Tempe, Arizona
Near the end, short detour
Yuma, Arizona
Hours: 10 am–5 pm
+19287268831
Visit websiteNear the start, short detour
Tempe, Arizona
+14803556060
Visit websiteNear the start, short detour
Mesa, Arizona
Hours: 6 am–10 pm
+14806442352
Visit websiteNear the start, short detour
Mesa, Arizona
Hours: 11 am–6 pm
+14805974467
Visit websiteNear the start, ~9 min detour
Tempe, Arizona
Hours: 11 am–5 pm
+14805657081
Visit websiteNear the end, ~11 min detour
Yuma, Arizona
Place data sourced from public business listings. Hours and availability may vary.
5 decision points cluster between mile 2.3 and 193.4 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
Take the ramp toward US 60 West: Phoenix
Lane positioning matters here
Take the exit toward I 10 East: Tucson
Exit ramp - move to the correct lane early. Lane positioning matters here
Take the exit toward AZ 347 South
Exit ramp - move to the correct lane early. Lane positioning matters here
At end of road, turn right onto AZ 84 / Gila Bend–Casa Grande Highway
Lane positioning matters here
Keep slight left at fork toward AZ 195: Araby Road, San Luis
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Regular Gas
$39.02 one way
$78.04 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.82 | $41.79 | $83.57 |
| premium | $5.04 | $43.71 | $87.42 |
| diesel | $4.80 | $41.58 | $83.16 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$39
Meals
$25–$50
Total
$64–$89
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 77 kg one way. Prices: EIA weekly data, 2026-07-13.
Driving Electric?
About $23 in charging · 0 stops · 66% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 66.1 | 0 | $23.12 | $10.57 |
| Efficient EV | 55.1 | 0 | $19.27 | $8.81 |
| EV Truck/SUV | 88.1 | 1 | $30.83 | $14.09 |
Gas CO2
77 kg
EV CO2
26 kg (66% less)
Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Late night in Tempe on Sunday
Local time
1:15 AM
MST
Current temp
95°F
Mostly Sunny
Flash Flood Warning
Flash Flood Warning issued July 18 at 1:59PM MST until July 18 at 4:00PM MST by NWS Tucson AZ
Flash Flood Warning
Flash Flood Warning issued July 18 at 1:57PM MST until July 18 at 3:00PM MST by NWS Tucson AZ
Destination
Late night in San Luis on Sunday
Local time
1:15 AM
MST
Current temp
106°F
Sunny
Flash Flood Warning
Flash Flood Warning issued July 18 at 1:59PM MST until July 18 at 4:00PM MST by NWS Tucson AZ
Flash Flood Warning
Flash Flood Warning issued July 18 at 1:57PM MST until July 18 at 3:00PM MST by NWS Tucson AZ
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Worth a detour if your schedule allows.
National Monument
An Ancestral Sonoran Desert People's farming community and "Great House" are preserved at Casa Grande Ruins. Whether a gathering place for people or simply a waypoint marker in an extensive system of...
Park data from the National Park Service API. Alerts update every 2 hours.
About 20% of this 220.2-mile route is on highways. You'll experience a longest stretch of 111.9 miles on the Blue Star Memorial Highway before transitioning to surface roads. This means you'll encounter a significant amount of city driving and traffic signals, particularly as you navigate through urban areas and their bypasses. Be prepared for frequent stops and starts as you move between different road types.
Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 2.3 miles in.
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 18 significant decision points across 220.2 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 2.3 miles: Lane positioning matters here; at 5.2 miles: Exit ramp - move to the correct lane early. Lane positioning matters here; at 14.9 miles: Exit ramp - move to the correct lane early. Lane positioning matters here.
Gently rolling terrain
Total Climb
675 ft
Total Descent
1,725 ft
Highest Point
1,781 ft
~62.9 mi in
Elevation Range
1,651 ft
Founded 1879
Tempe is a city of 180,587 (2020) in the Greater Phoenix area of Arizona, best known as the home of Arizona State University (ASU). Its younger, student-heavy population allows it to offer a vibrant nightlife that is relatively rare in Arizona.
Top landmarks
Founded 1930
San Luis is a town in Western Arizona. It is across the US-Mexico border from San Luis Rio Colorado, Sonora.
City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).
Weekend Trip
Doable as a same-day drive at 4h 4m. Total distance: 220.2 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
4h 4m drive, comfortable solo distance.
Scenic Drive
Mostly surface roads route profile with national parks nearby.
Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, USGS 3DEP for elevation, and NPS for national parks. See our methodology for refresh cadence and limitations.
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