Spanning 48.7 miles across the Northeast, this trip from Smithtown to Mount Vernon, New York, is an efficient journey that typically takes about 1 hour and 12 minutes. Because of the manageable duration, you can easily complete this drive in a single day without needing an overnight stay. Expect to spend approximately $8 on fuel for the trip, making it a budget-friendly option for your travel plans. You will navigate primarily via local roads like West Main Street, Jericho Turnpike, and SM South rather than relying on major interstates. It is a straightforward route that serves as a practical connection between these two New York locales.