Santa Ana to Burlingame is 404.4 miles and takes about 7h 38m via I-5 N and US 101 N, with a fuel budget near $93 and enough daylight to finish in a day. This drive keeps you on the go, with 99% of it on major freeways. You'll be traveling from the Pacific Coast region to the same region, staying within California for the entire trip. Expect a straightforward, efficient transit between Southern and Northern California. Given the duration and highway focus, it's well-suited for a single-day trip if you get an early start.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
2 planned breaks
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
202.2 miles from Santa Ana, CA
A natural place for your longest stop of the day
, about 3h 47m into the drive
.
Main Roads
Road
Distance
Duration
Westside Freeway
182.5 mi
3h 15m
Golden State Freeway
50 mi
57m
US 101
43 mi
49m
CA 152
41.1 mi
51m
I 5 Truck
37.7 mi
43m
Santa Ana Freeway
26.9 mi
31m
South Valley Freeway
19.9 mi
22m
North Broadway
1.5 mi
2m
Longest stretch:
Westside Freeway
— 182.5 mi, about 3h 15m
Turn-by-Turn Driving Directions
Step-by-step road directions between Santa Ana, CA and Burlingame, CA.
1
Start on West 1st Street
0.1 mi·15 sec·West 1st Street
2
Turn right onto North Broadway
1.5 mi·2 min·North Broadway
Use the straight / right lanes.
3
Turn right onto West Santa Clara Avenue
0.1 mi·14 sec·West Santa Clara Avenue
4
Continue on this road
0.3 mi·26 sec·this road
Toward I 5 North: Los AngelesUse the left / straight / right lanes.
5
Merge onto I 5
8.9 mi·10 min·Santa Ana Freeway
Use the straight / slight right lanes.
6
Keep slight right at fork onto I 5
18 mi·20 min·Santa Ana Freeway
Use the straight / slight right lanes.
7
Keep slight right at fork onto I 5
25 mi·29 min·Golden State Freeway
Use the straight / slight right lanes.
8
Keep slight left at fork onto I 5
2.2 mi·2 min·Golden State Freeway
Use the straight / slight right lanes.
9
Keep slight right at fork onto I 5 Truck
1.5 mi·1 min·I 5 Truck
Exit 161AToward I 5 Truck North, CA 14 TruckUse the straight / slight right lanes.
10
Keep slight left at fork onto I 5 Truck
36 mi·41 min·I 5 Truck
Use the straight / slight right lanes.
11
Keep slight left at fork onto I 5
22 mi·25 min·Golden State Freeway
Use the straight / slight right lanes.
12
Keep slight right at fork onto I 5
183 mi·3 hr 15 min·Westside Freeway
Toward I 5 NorthUse the straight / slight right lanes.
13
Take the exit
0.2 mi·26 sec
Exit 403BToward CA 152 West: Gilroy, Hollister, San Jose
14
Continue on CA 152; CA33
29 mi·33 min·CA 152; CA33
Use the straight lane.
15
Keep slight right at fork onto CA 152
12 mi·16 min·CA 152
16
Take the exit onto CA 152
0.5 mi·1 min·CA 152
Toward US 101 North: San Jose
17
Merge onto US 101; CA 152
20 mi·22 min·South Valley Freeway
Use the slight right lane.
18
Keep slight left at fork onto US 101
22 mi·25 min·US 101
Use the straight / slight right lanes.
19
Keep slight left at fork onto US 101
21 mi·24 min·US 101
Use the slight left lane.
20
Take the exit
0.3 mi·48 sec
Exit 419BToward Broadway, Airport BoulevardUse the straight / slight right lanes.
21
Turn right onto Old Bayshore Highway
0.1 mi·19 sec·Old Bayshore Highway
Use the straight / left / right lanes.
22
Turn right onto Broadway
0.6 mi·1 min·Broadway
Use the right lane.
23
Turn left onto CA 82
70 ft·1 sec·El Camino Real
24
Arrive at destination
CA 82
Trip Plan
To make the most of this 404.4-mile drive, aim to depart Santa Ana early, ideally before 7 AM, to navigate Southern California's morning traffic. With a total estimated drive time of 7 hours and 38 minutes, you can comfortably complete this trip in one day. Consider taking your two recommended stops strategically, perhaps around the halfway point, to stretch and refuel. Keep an eye on your fuel gauge, especially during the 182.5-mile stretch on the Westside Freeway, and factor in the approximate $93 fuel cost for your planning. The high highway share means you'll have plenty of opportunities to maintain momentum.
Morning Departure
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Evening Departure
This is a long drive — plan for a morning departure or consider splitting it into two days.
You can normally do this drive in one day.
Plan roughly 2 meaningful breaks for fuel, food, and rest.
The halfway point lands around 202.2 miles from Santa Ana, CA, or about 3h 47m into the drive.
The longest continuous stretch on this route runs about 182.5 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 89 miles or 1h 44m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 202.2 miles or 3h 47m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 6h 27m
Traffic, exits, and arrival timing usually matter more near Burlingame, CA than in the middle of the route.
Before You Leave
+
Open the route before leaving Santa Ana, CA so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
+
Pick one backup stop option before the midpoint in case traffic changes your pacing.
Day 1
Settle into the route from Santa Ana, CA
This is one driving day of about 404.4 miles and 7h 38m.
Your first comfortable stop window is around 89 miles from Santa Ana, CA.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 2 real breaks rather than only quick fuel stops.
The longest stretch is on Westside Freeway for about 182.5 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 21
5 decision points cluster between mile 0.1 and 403.4 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
6
0.1 mi into trip|~0m in|North Broadway
Turn right onto North Broadway
Lane positioning matters here
Use the straight / right lanes.
6
11 mi into trip|~14m in|I 5 / Santa Ana Freeway
Keep slight right at fork onto I 5 / Santa Ana Freeway
Highway fork - watch signs carefully. Lane positioning matters here
Use the straight / slight right lanes.
9
56.6 mi into trip|~1h 7m in|I 5 Truck
Keep slight right at fork onto I 5 Truck toward I 5 Truck North, CA 14 Truck
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / slight right lanes.
Exit 161A
Toward I 5 Truck North, CA 14 Truck
7
116.6 mi into trip|~2h 16m in|I 5 / Westside Freeway
Keep slight right at fork onto I 5 / Westside Freeway toward I 5 North
Highway fork - watch signs carefully. Lane positioning matters here
Use the straight / slight right lanes.
Toward I 5 North
8
403.4 mi into trip|~7h 35m in
Take the exit toward Broadway, Airport Boulevard
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / slight right lanes.
Exit 419B
Toward Broadway, Airport Boulevard
Fuel & Cost
Regular Gas
$92.95 one way
$185.90 round trip
$5.84/gal25.4 MPG avg142 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$6.02
$95.78
$191.56
premium
$6.18
$98.35
$196.69
diesel
$5.61
$89.29
$178.57
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$93
Meals
$25–$50
Total
$118–$143
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 141.5 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $42 in charging
· 1 stop
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
121.3
1
$42.46
$19.41
Efficient EV
101.1
1
$35.39
$16.18
EV Truck/SUV
161.8
2
$56.62
$25.88
Gas CO2
141 kg
EV CO2
47 kg (67% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 19, 2026
Origin
Santa Ana, CA
Late night
in Santa Ana on Tuesday
Local time
3:42 AM
PDT
Current temp
55°F
Unavailable
Live forecast
Destination
Burlingame, CA
Late night
in Burlingame on Tuesday
Local time
3:42 AM
PDT
Current temp
--
Unavailable
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Road read
7h 38m on the road
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
San Francisco Maritime National Historical Park
National Historical Park
Established in 1988, San Francisco Maritime National Historical Park celebrates America’s maritime heritage on the Pacific Coast. Our 50-acre park has grown around Aquatic Park Cove, a protected area...
16 mi from route
~40 min detour
Free
near mile 404.4
The Santa Monica Mountains offer easy access to surprisingly wild places. Experience the famous beaches of Malibu or explore more than 500 miles of trails. The park abounds with historical and cultura...
22 mi from route
~55 min detour
Free
near mile 55.8
Experience a park so rich it supports 19 distinct ecosystems with over 2,000 plant and animal species. Go for a hike, enjoy a vista, have a picnic or learn about the centuries of overlapping history f...
23 mi from route
~57 min detour
Free
near mile 404.4
Rosie the Riveter WWII Home Front National Historical Park
National Historical Park
Celebrate and honor the contributions and sacrifices of American civilians on the WWII home front. Discover how diverse communities lived, worked, and interacted. Many faces, many stories, many truths...
23 mi from route
~56 min detour
Free
near mile 404.4
Walk among old growth coast redwoods, cooling their roots in the fresh water of Redwood Creek and lifting their crowns to reach the sun and fog. Federally protected as a National Monument since 1908,...
25 mi from route
~61 min detour
$15
near mile 404.4
Yes, we can! Widely recognized as the most important Latino leader in the United States during the twentieth century, Cesar Chavez led farm workers and supporters in the establishment of the country's...
29 mi from route
~72 min detour
Free
near mile 125.5
Park data from the National Park Service API. Alerts update every 2 hours.
More Details
What kind of drive is this?
This is a highway-heavy drive, with 99% of the 404.4 miles on major freeways like the Golden State Freeway and US 101. You'll encounter your longest continuous stretch of freeway at 182.5 miles, likely on the Westside Freeway. Expect consistent cruising speeds and frequent, dense exits as you move through various urban and suburban areas. The profile is mostly highway, meaning minimal time spent on surface streets.
99% highway — fuel and pacing are the main things to plan.
24 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 182.5 mi on Westside Freeway.
How Hard Is This Drive?
9/10
This is a straightforward highway drive that stays mostly on Westside Freeway and Golden State Freeway. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 0.1 miles in near North Broadway.
Driving Effort9/10
High effort - long or complex enough to need steady focus all day
Balances navigation complexity with total wheel time.
This is a demanding drive. With 21 significant decision points across 404.4 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 0.1 miles (North Broadway): Lane positioning matters here; at 11 miles (I 5 / Santa Ana Freeway): Highway fork - watch signs carefully. Lane positioning matters here; at 56.6 miles (I 5 Truck): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one.
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Santa Ana, CA and Burlingame, CA, road signs point toward Hollister and San Jose.
Burlingame is a city of 31,000 people (2020) in California's Bay Area on the Peninsula. This suburb of San Francisco is known for its numerous eucalyptus groves, and walkable downtown area.
Top landmarks
•Burlingame station — railway station in Burlingame, California
Doable as a same-day drive at 7h 38m. Total distance: 404.4 miles.
Family Friendly
Moderate complexity with 2 natural rest stops along the way.
Solo Traveler
7h 38m drive, plan rest stops for pacing.
Frequently Asked Questions
The longest stretch is about 182.5 miles on Westside Freeway. The full list of main roads is in the Roads section above.
Yes — we found about 27 rest areas or service plazas within a short detour of the route (from OpenStreetMap). See the Rest Stops tab under Nearby Places for locations and mile markers. Plan to stretch, use the bathroom, and top off fluids every 2–3 hours on longer drives.
It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Burlingame, CA before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 2 meaningful breaks. There are 27 rest areas along the route for bathroom stops.
The main spots that need attention: at 0.1 miles (North Broadway): Lane positioning matters here; at 11 miles (I 5 / Santa Ana Freeway): Highway fork - watch signs carefully. Lane positioning matters here; at 56.6 miles (I 5 Truck): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one.
Yes — San Francisco Maritime National Historical Park, Santa Monica Mountains National Recreation Area and Golden Gate National Recreation Area (6 total within detour distance). See the National Parks section for detour distances and tips on detours.
Not recommended in a single day. At 7.6 hours each way, a round trip means 15.3 hours of driving — that is an unsafe level of fatigue for most drivers. Plan at least one night at Burlingame, CA before the return drive.
