Niles, IL to Lily Lake, IL is 47.2 miles and takes about 1 hour 4 minutes via Jane Addams Memorial Tollway and Randall Road, with a fuel budget near $7 and enough daylight to finish in a day. This short trip stays within Illinois, moving from the Midwest's more populated areas towards a more rural destination. The route is primarily surface roads after an initial highway stretch, making it a straightforward drive for a single day. Consider this route if you're looking for a quick transition from suburban Chicago to a quieter setting without a long travel commitment.