This 70.9-mile drive from Niles, IL, to Caledonia, IL, will take you about 1 hour and 27 minutes. Designed as a single-day trip, you can expect to spend approximately $11 on fuel for this journey. The route primarily utilizes the Jane Addams Memorial Tollway, Fairgrounds Road, and Belvidere Road, offering a blend of highway and local road experiences. Given its manageable distance and duration, it's a straightforward trip for anyone looking to explore within the Midwest region of Illinois. This route is ideal if you're seeking a relatively quick and efficient way to travel between these two points without needing an overnight stay.