Mobile, AL to Fyffe, AL is 357.1 miles and takes about 6h 33m via I 65 and I 59, with a fuel budget near $54 and enough daylight to finish in a day. This trip stays within Alabama, moving from the Southeast region to another part of the Southeast. You'll primarily be on major interstates for this drive, making for a straightforward connection between these two points. With a recommended single day of driving, it’s a manageable distance for most vehicles.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
178.5 miles from Mobile, AL
A natural place for your longest stop of the day
, about 3h 14m into the drive
.
Main Roads
Road
Distance
Duration
I 65
239.6 mi
4h 18m
I 59
80.8 mi
1h 26m
John M. Harbert III Freeway
17.1 mi
18m
I 165
4.5 mi
5m
East Main Street
3.8 mi
5m
Glenn Boulevard Southwest
3.8 mi
5m
Main Street
3 mi
5m
McCurdy Avenue South
1.7 mi
2m
Longest stretch:
I 65
— 239.6 mi, about 4h 18m
Turn-by-Turn Driving Directions
Step-by-step road directions between Mobile, AL and Fyffe, AL.
1
Start on Saint Louis Street
389 ft·22 sec·Saint Louis Street
2
Turn left onto North Royal Street
0.2 mi·41 sec·North Royal Street
3
Turn right onto Congress Street
260 ft·11 sec·Congress Street
4
Take the ramp
411 ft·12 sec
5
Merge onto North Water Street
0.1 mi·19 sec·North Water Street
6
Continue on US 90; US 98 Truck
482 ft·11 sec·Telegraph Road
7
Turn straight onto I 165; US 90; US 98 Truck
4.5 mi·5 min·I 165; US 90; US 98 Truck
8
Keep slight right at fork
0.5 mi·33 sec
Exit 1BToward I 65: Montgomery
9
Merge onto I 65
240 mi·4 hr 18 min·I 65
Use the straight / slight right lanes.
10
Take the exit
0.2 mi·32 sec
Exit 250Toward I 459: Atlanta, Gadsden, TuscaloosaUse the straight / slight right lanes.
11
Keep slight right at fork
0.6 mi·1 min
Toward I 459 North: Atlanta, GadsdenUse the slight left / slight right lanes.
12
Merge onto I 459
17 mi·18 min·John M. Harbert III Freeway
Use the straight / slight right lanes.
13
Keep slight right at fork
0.3 mi·41 sec
Exit 33BToward I 59 North: GadsdenUse the slight right lane.
14
Continue on this road
0.2 mi·15 sec·this road
Exit 33AToward I-59 North: Gadsden
15
Merge onto I 59
81 mi·1 hr 26 min·I 59
Use the straight / slight right lanes.
16
Take the exit
0.3 mi·33 sec
Exit 218Toward 35: Fort Payne, Rainsville
17
Turn left onto AL 35
3.8 mi·5 min·Glenn Boulevard Southwest
18
Continue on AL 35
3.8 mi·5 min·East Main Street
19
Turn left onto AL 75
1.7 mi·2 min·McCurdy Avenue South
20
Continue on AL 75
3.0 mi·5 min·Main Street
21
Arrive at destination
AL 75
Trip Plan
To make the most of this 6h 33m drive, consider an early morning departure from Mobile to ensure you have ample daylight. While the route is feasible in one day, the 239.6-mile stretch on I 65 means you'll have a significant period of continuous driving. Break up the drive with a stop around the halfway point, which will likely be somewhere along I 59. Keep an eye on your fuel, especially before entering longer stretches where services might be less frequent.
Morning Departure
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Evening Departure
This is a long drive — plan for a morning departure or consider splitting it into two days.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 178.5 miles from Mobile, AL, or about 3h 14m into the drive.
The longest continuous stretch on this route runs about 239.6 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 79 miles or 1h 26m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 178.5 miles or 3h 14m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 5h 23m
Traffic, exits, and arrival timing usually matter more near Fyffe, AL than in the middle of the route.
Before You Leave
+
Open the route before leaving Mobile, AL so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Mobile, AL
This is one driving day of about 357.1 miles and 6h 33m.
Your first comfortable stop window is around 79 miles from Mobile, AL.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on I 65 for about 239.6 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 14
5 decision points cluster between mile 5.1 and 344.5 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
6
5.1 mi into trip|~7m in
Keep slight right at fork toward I 65: Montgomery
Highway fork - watch signs carefully
Exit 1B
Toward I 65: Montgomery
8
245.2 mi into trip|~4h 26m in
Take the exit toward I 459: Atlanta, Gadsden, Tuscaloosa
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / slight right lanes.
Exit 250
Toward I 459: Atlanta, Gadsden, Tuscaloosa
8
245.5 mi into trip|~4h 26m in
Keep slight right at fork toward I 459 North: Atlanta, Gadsden
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight left / slight right lanes.
Toward I 459 North: Atlanta, Gadsden
8
263.2 mi into trip|~4h 46m in
Keep slight right at fork toward I 59 North: Gadsden
Highway fork - watch signs carefully. Lane positioning matters here
Use the slight right lane.
Exit 33B
Toward I 59 North: Gadsden
6
344.5 mi into trip|~6h 14m in
Take the exit toward 35: Fort Payne, Rainsville
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Exit 218
Toward 35: Fort Payne, Rainsville
Fuel & Cost
Regular Gas
$53.93 one way
$107.86 round trip
$3.84/gal25.4 MPG avg125 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.21
$59.20
$118.41
premium
$4.56
$64.10
$128.19
diesel
$5.61
$78.84
$157.69
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$54
Meals
$25–$50
Total
$79–$104
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 124.9 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $38 in charging
· 1 stop
· 66% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
107.1
1
$37.50
$17.14
Efficient EV
89.3
1
$31.25
$14.28
EV Truck/SUV
142.8
1
$49.99
$22.85
Gas CO2
125 kg
EV CO2
42 kg (66% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 19, 2026
Origin
Mobile, AL
Late night
in Mobile on Tuesday
Local time
4:46 AM
CDT
Current temp
66°F
Unavailable
Live forecast
Destination
Fyffe, AL
Late night
in Fyffe on Tuesday
Local time
4:46 AM
CDT
Current temp
54°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
12 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
6h 33m on the road
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
More Details
What kind of drive is this?
This is a predominantly highway drive, with 96% of the 357.1 miles on interstates. You'll experience a longest stretch of 239.6 miles on I 65 before transitioning to I 59. Expect dense exits and merges as you navigate urban areas and then settle into more consistent cruising speeds on the interstate. Surface roads will only constitute a small fraction of your time behind the wheel.
96% highway — fuel and pacing are the main things to plan.
21 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 239.6 mi on I 65.
How Hard Is This Drive?
9/10
This is a straightforward highway drive that stays mostly on I 65 and I 59. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 5.1 miles in.
Driving Effort9/10
High effort - long or complex enough to need steady focus all day
Balances navigation complexity with total wheel time.
This is a demanding drive. With 14 significant decision points across 357.1 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 5.1 miles: Highway fork - watch signs carefully; at 245.2 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 245.5 miles: Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one.
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Mobile, AL and Fyffe, AL, road signs point toward Gadsden and Tuscaloosa.
For issues specific to mobile phones and smartphone usage, see Mobile phones.
Mobile is a city in the state of Alabama in the South of the United States of America with almost a half million people in the metro area.
Mobile is a historic, diverse port city with a strong southern culture and heritage. The original capital of French Louisiana, Mobile is home to the oldest Mardi Gras celebration in the United States.
Doable as a same-day drive at 6h 33m. Total distance: 357.1 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
6h 33m drive, plan rest stops for pacing.
Frequently Asked Questions
The longest stretch is about 239.6 miles on I 65. The full list of main roads is in the Roads section above.
Yes — we found about 23 rest areas or service plazas within a short detour of the route (from OpenStreetMap). See the Rest Stops tab under Nearby Places for locations and mile markers. Plan to stretch, use the bathroom, and top off fluids every 2–3 hours on longer drives.
It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Fyffe, AL before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. There are 23 rest areas along the route for bathroom stops.
The main spots that need attention: at 5.1 miles: Highway fork - watch signs carefully; at 245.2 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 245.5 miles: Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one.
Not recommended in a single day. At 6.6 hours each way, a round trip means 13.1 hours of driving — that is an unsafe level of fatigue for most drivers. Plan at least one night at Fyffe, AL before the return drive.
