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Trip from Middleburg, FL to Gainesville, FL

Compiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Apr 19, 2026 · Editorial standards

Drive Time

1h 6m

Distance

44.7 mi

72 km

Drive Score

8/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$7

one way

EV Charging

Good

8 stations

Best Time to Leave

Save up to 16 min
4 AM
1h 1m ★
6 AM
1h 6m
8 AM
1h 17m
10 AM
1h 10m
12 PM
1h 9m
3 PM
1h 10m
5 PM
1h 16m
8 PM
1h 3m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

Downtown Middleburg, FL, FL

Middleburg, FL

Matt Fitz Gibaud

Trip Overview

Traveling from Middleburg to Gainesville covers a compact 44.7 miles, making it an easy trip to complete in about 58 minutes. Since this is a short distance, a single day is more than enough time to make the trek and return if needed. You can expect to spend roughly $7 on fuel, keeping this an affordable regional excursion within Florida. Because the route relies entirely on local roads rather than interstates, you should prepare for a steady, turn-heavy pace. This drive is ideal for those who prefer navigating through local corridors rather than handling high-speed highway traffic.

Main Roads

Road Distance Duration
Waldo Road 12.1 mi 16m
FL 16 9.4 mi 13m
US 301 9.1 mi 11m
CR 215 6.1 mi 9m
Temple Avenue 3 mi 5m
Blanding Boulevard 2.7 mi 4m
East University Avenue 0.8 mi 2m
Northeast Waldo Road 0.5 mi <1m
Longest stretch: Waldo Road — 12.1 mi, about 16m

Turn-by-Turn Driving Directions

Step-by-step road directions between Middleburg, FL and Gainesville, FL.

1

Start on Wharf Street

119 ft · 10 sec · Wharf Street
2

Turn left onto Main Street

0.4 mi · 1 min · Main Street
3

At end of road, turn slight left onto FL 21

2.7 mi · 4 min · Blanding Boulevard
4

Turn right onto CR 215

6.1 mi · 9 min · CR 215
5

Turn straight onto FL 16

9.4 mi · 13 min · FL 16
6

Turn left onto US 301

3.0 mi · 5 min · Temple Avenue
7

At end of road, turn left onto US 301

9.1 mi · 11 min · US 301
Use the left lane.
8

Keep slight right at fork onto FL 24

0.5 mi · 1 min · Kennard Street
9

Continue on FL 24

11 mi · 14 min · Waldo Road
Use the right lane.
10

Continue on FL 24

0.5 mi · 54 sec · Northeast Waldo Road
11

Continue on FL 24

1.2 mi · 2 min · Waldo Road
Use the left lane.
12

Turn right onto FL 20; FL 24; FL 26

0.8 mi · 2 min · East University Avenue
Use the right lane.
13

Turn left onto CR 329

115 ft · 3 sec · South Main Street
14

Arrive at destination

CR 329

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

city in and the county seat of Bradford County, Florida, United States

Mid-route town

Meal stop

Starke, FL

22 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Popular next leg

Starke, FL to Gainesville, FL

25.6 mi · 37m

Pacing Suggestions

Starke, FL

Fuel and coffee

A short stop after about 10 miles helps settle the day before fatigue starts building.

Starke, FL

Meal break

The midpoint is around 22.3 miles from Middleburg, FL, which is a good place for a longer meal and fuel stop.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Heads-up: tricky spots

5 of 8

5 decision points cluster between mile 0.4 and 43.8 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.

4
0.4 mi into trip | ~1m in | FL 21 / Blanding Boulevard

At end of road, turn slight left onto FL 21 / Blanding Boulevard

Navigation decision point

4
18.6 mi into trip | ~28m in | US 301 / Temple Avenue

Turn left onto US 301 / Temple Avenue

Navigation decision point

5
21.6 mi into trip | ~33m in | US 301

At end of road, turn left onto US 301

Lane positioning matters here

Use the left lane.
4
30.7 mi into trip | ~45m in | FL 24 / Kennard Street

Keep slight right at fork onto FL 24 / Kennard Street

Highway fork - watch signs carefully

5
43.8 mi into trip | ~1h 4m in | FL 20; FL 24; FL 26 / East University Avenue

Turn right onto FL 20; FL 24; FL 26 / East University Avenue

Lane positioning matters here

Use the right lane.

Fuel & Cost

Regular Gas

$7.12 one way

$14.23 round trip

$4.04/gal 25.4 MPG avg 16 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.40 $7.74 $15.48
premium $4.72 $8.31 $16.62
diesel $5.61 $9.87 $19.74

No toll roads detected on this route.

Drive Cost (one way)

Fuel

$7

Estimated CO2 emission: 15.6 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $5 in charging · 0 stops · 69% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 13.4 0 $4.69 $2.15
Efficient EV 11.2 0 $3.91 $1.79
EV Truck/SUV 17.9 0 $6.26 $2.86

Gas CO2

16 kg

EV CO2

5 kg (69% less)

This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Apr 15, 2026

Origin

Middleburg, FL

Late night in Middleburg on Sunday

Local time

1:58 AM

EDT

Current temp

79°F

Unavailable

Live forecast

Destination

Gainesville, FL

Late night in Gainesville on Sunday

Local time

1:58 AM

EDT

Current temp

81°F

Unavailable

Live forecast

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

2 degrees warmer at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

1h 6m on the road

Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

What kind of drive is this?

Expect a highly technical and turn-heavy experience as you navigate exclusively on local roads. You will spend your time winding through Main Street, Blanding Boulevard, and Temple Avenue, with zero percent of the trip taking place on a highway. Because there is no highway travel, there are no long, uninterrupted stretches, meaning your longest segment on any single road is quite short. You will need to stay alert behind the wheel, as the nature of these local roads requires consistent attention to turns and transitions. It is a very hands-on drive that keeps you engaged with local traffic patterns throughout the entire 58-minute duration.

55% highway, the rest on surface roads — varied driving throughout.
14 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 12.1 mi on Waldo Road.

How Hard Is This Drive?

6/10

This route mixes highway mileage with some local-road sections near the start or finish. You will hit about 8 points where you need to pay attention to lane position or signs. The trickiest moment comes around 0.4 miles in near FL 21 / Blanding Boulevard.

Driving Effort 6/10

Moderate - straightforward overall, but long enough or busy enough to require pacing

Balances navigation complexity with total wheel time.

This drive requires moderate attention. Across 44.7 miles you will encounter 8 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.

Where does it get tricky?

The main spots that need attention: at 0.4 miles (FL 21 / Blanding Boulevard): Navigation decision point; at 18.6 miles (US 301 / Temple Avenue): Navigation decision point; at 21.6 miles (US 301): Lane positioning matters here.

About the Cities

Arriving in Gainesville, FL

Full guide →

Gainesville is in North Central Florida. It is home to the University of Florida, and Santa Fe College.

City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).

Who Is This Route For?

Weekend Trip

Doable as a same-day drive at 1h 6m. Total distance: 44.7 miles.

Family Friendly

Moderate complexity with 0 natural rest stops along the way.

Solo Traveler

1h 6m drive, comfortable solo distance.

EV Driver

0 DC fast chargers along the route. Coverage: unknown.

First-Time Driver

Mostly highway driving (55%). Some complex stretches to watch for.

Frequently Asked Questions

The longest stretch is about 12.1 miles on Waldo Road. The full list of main roads is in the Roads section above.

It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Gainesville, FL before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.

Yes. At under 2 hours behind the wheel, this works well for families — plan one quick stop if you have younger kids.

The main spots that need attention: at 0.4 miles (FL 21 / Blanding Boulevard): Navigation decision point; at 18.6 miles (US 301 / Temple Avenue): Navigation decision point; at 21.6 miles (US 301): Lane positioning matters here.

Yes. A round trip is manageable in a single day if you plan a break at Gainesville, FL before heading back.

How this page is built

Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, and EIA for fuel prices. See our methodology for refresh cadence and limitations.

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