If you are planning a quick excursion from Maysville to Lexington, Kentucky, you are looking at a straightforward 69.4-mile trek. The drive typically takes about 1 hour and 33 minutes, making it an ideal day trip that requires no overnight stay. You will primarily navigate via US 68 and US 68 Business, which keeps the logistics simple and predictable. With an estimated fuel cost of just $11, this is an affordable way to transit between these two Southeast locations. Whether you are heading into the city for business or leisure, this route provides a direct connection without unnecessary detours.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Midpoint
34.7 miles from Maysville, KY
A natural place for your longest stop of the day
, about 46m into the drive
.
Main Roads
Road
Distance
Duration
US 68
22.8 mi
27m
US 68 Business
17.2 mi
23m
Lexington Road
6.8 mi
7m
Paris Pike
5.9 mi
6m
West New Circle Road
5.2 mi
8m
Coughlin Boulevard
2.9 mi
4m
US 62
1.7 mi
2m
North Broadway
1.4 mi
2m
Longest stretch:
US 68
— 22.8 mi, about 27m
Turn-by-Turn Driving Directions
Step-by-step road directions between Maysville, KY and Lexington, KY.
1
Start on KY 10
0.8 mi·1 min·Forest Avenue
2
Turn sharp left onto US 62; KY 10
2.9 mi·4 min·Coughlin Boulevard
Use the left lane.
3
Continue on US 62; US 68
1.7 mi·2 min·US 62; US 68
Use the straight / left / right lanes.
4
Continue on US 68 Business
17 mi·23 min·US 68 Business
5
Continue on US 68; KY 165
23 mi·27 min·US 68; KY 165
6
Continue on US 460; US 68 Business
0.8 mi·1 min·East Main Street
7
Turn right onto US 460; US 68 Business
0.7 mi·1 min·Bank Row Street
8
At end of road, turn right onto US 68 Business
1.1 mi·1 min·Main Street
9
Continue on US 27; US 68
6.8 mi·7 min·Lexington Road
10
Continue on US 27; US 68
5.9 mi·6 min·Paris Pike
11
Continue on US 27; US 68
1.4 mi·2 min·North Broadway
12
Turn left onto KY 4
5.2 mi·8 min·West New Circle Road
Use the straight / slight right lanes.
13
Take the exit
0.2 mi·37 sec
Exit 16Toward Alumni DriveUse the straight / slight right lanes.
14
Turn left onto Alumni Drive
0.4 mi·48 sec·Alumni Drive
15
Turn right onto Yellowstone Parkway
0.3 mi·48 sec·Yellowstone Parkway
16
Turn right onto Pimlico Parkway
0.9 mi·1 min·Pimlico Parkway
17
Turn right onto Gainesway Drive
0.1 mi·18 sec·Gainesway Drive
18
Turn right onto Coldstream Drive
261 ft·9 sec·Coldstream Drive
19
Arrive at destination
Coldstream Drive
Trip Plan
Since this is a relatively short trip, you have plenty of flexibility in your schedule, but aiming to leave during off-peak hours can help you maintain that 1 hour and 33 minute duration. Because there are no mandatory stops scheduled, you can easily complete the entire 69.4 miles in one go, though keeping an eye on your fuel gauge is wise even with the low $11 cost estimate. Before departing Maysville, ensure your vehicle is ready for the 22.8-mile stretch on US 68, as this is your longest period without a break. Use the simplicity of this route to your advantage by planning your arrival in Lexington around your specific personal itinerary.
Morning Departure
Leave by 9 AM and you'll arrive before lunch.
Evening Departure
Even a 4 PM departure gets you there before dark in summer.
You can normally do this drive in one day.
You may only need one short stretch break if traffic stays light.
The halfway point lands around 34.7 miles from Maysville, KY, or about 46m into the drive.
The longest continuous stretch on this route runs about 22.8 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 15 miles or 21m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 34.7 miles or 46m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 1h 15m
Traffic, exits, and arrival timing usually matter more near Lexington, KY than in the middle of the route.
Before You Leave
+
Open the route before leaving Maysville, KY so your first major turns are already loaded.
Day 1
Settle into the route from Maysville, KY
This is one driving day of about 69.4 miles and 1h 33m.
Your first comfortable stop window is around 15 miles from Maysville, KY.
This route can stay practical as a one-day drive if traffic stays reasonable.
The longest stretch is on US 68 for about 22.8 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 10
5 decision points cluster between mile 0.8 and 68 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
7
0.8 mi into trip|~1m in|US 62; KY 10 / Coughlin Boulevard
Turn sharp left onto US 62; KY 10 / Coughlin Boulevard
Sharp turn - reduce speed on approach. Lane positioning matters here
Use the left lane.
4
46.9 mi into trip|~1h 1m in|US 68 Business / Main Street
At end of road, turn right onto US 68 Business / Main Street
Navigation decision point
4
62.1 mi into trip|~1h 19m in|KY 4 / West New Circle Road
Turn left onto KY 4 / West New Circle Road
Lane positioning matters here
Use the straight / slight right lanes.
7
67.4 mi into trip|~1h 28m in
Take the exit toward Alumni Drive
Exit ramp - move to the correct lane early. Lane positioning matters here
Use the straight / slight right lanes.
Exit 16
Toward Alumni Drive
4
68 mi into trip|~1h 30m in|Yellowstone Parkway
Turn right onto Yellowstone Parkway
Navigation decision point
Fuel & Cost
Regular Gas
$10.85 one way
$21.70 round trip
$3.97/gal25.4 MPG avg24 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.36
$11.91
$23.83
premium
$4.89
$13.36
$26.71
diesel
$5.61
$15.32
$30.65
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$11
Meals
$25–$50
Total
$36–$61
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 24.3 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $7 in charging
· 0 stops
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
20.8
0
$7.29
$3.33
Efficient EV
17.4
0
$6.07
$2.78
EV Truck/SUV
27.8
0
$9.72
$4.44
Gas CO2
24 kg
EV CO2
8 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 15, 2026
Origin
Maysville, KY
Afternoon
in Maysville on Sunday
Local time
4:24 PM
EDT
Current temp
51°F
Unavailable
Live forecast
Destination
Lexington, KY
Afternoon
in Lexington on Sunday
Local time
4:24 PM
EDT
Current temp
73°F
Unavailable
Live forecast
72°F
Carlisle, KY
35 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
22 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
1h 33m on the road
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
More Details
What kind of drive is this?
This trip is a highway-focused drive, with 62% of your journey spent on faster, more open roads. You will settle into a steady rhythm on the pavement, with your longest uninterrupted stretch covering 22.8 miles along US 68. As you transition from the local routes onto Lexington Road, the character of the drive shifts from smaller thoroughfares to a more consistent highway experience. Behind the wheel, you can expect a functional, efficient drive that prioritizes steady progress over technical maneuvering. It is a manageable stretch that avoids the monotony of a massive interstate while maintaining a reliable pace.
62% highway — fuel and pacing are the main things to plan.
19 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 22.8 mi on US 68.
How Hard Is This Drive?
4/10
This is a straightforward highway drive that stays mostly on US 68 and US 68 Business. There are only a few real navigation decisions along the way. The trickiest moment comes around 0.8 miles in near US 62; KY 10 / Coughlin Boulevard.
Driving Effort4/10
Easy - simple navigation with a manageable amount of wheel time
Balances navigation complexity with total wheel time.
This is a straightforward 1h 33m drive. You will face about 10 decision points, but nothing that requires special attention if you follow navigation.
Where does it get tricky?
The main spots that need attention: at 0.8 miles (US 62; KY 10 / Coughlin Boulevard): Sharp turn - reduce speed on approach. Lane positioning matters here; at 46.9 miles (US 68 Business / Main Street): Navigation decision point; at 62.1 miles (KY 4 / West New Circle Road): Lane positioning matters here.
Lexington is the second largest city in Kentucky, located in the Bluegrass Region. Known as the Horse Capital of the World, Lexington has traditionally been dominated by the horse industry and is also heavily influenced by the University of Kentucky, the state's flagship university and the largest employer in the city. The horse industry has greatly influenced Lexington's culture and scenic beauty; the University of Kentucky and Transylvania University contribute to a college town atmosphere with a richer and more diverse culture than some might expect from its size and location. Lexington's compact central downtown district is surrounded by historic neighborhoods. Lexington is in the heart of the Bluegrass region of Kentucky and is still home to hundreds of horse farms.
The longest stretch is about 22.8 miles on US 68. The full list of main roads is in the Roads section above.
Yes. At under 2 hours behind the wheel, this works well for families — plan one quick stop if you have younger kids.
The main spots that need attention: at 0.8 miles (US 62; KY 10 / Coughlin Boulevard): Sharp turn - reduce speed on approach. Lane positioning matters here; at 46.9 miles (US 68 Business / Main Street): Navigation decision point; at 62.1 miles (KY 4 / West New Circle Road): Lane positioning matters here.
Yes. A round trip is manageable in a single day if you plan a break at Lexington, KY before heading back.
