Origin
Manhattan, NY
Late night in Manhattan on Sunday
Local time
3:29 AM
EDT
Current temp
49°F
Unavailable
Compiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Apr 19, 2026 · Editorial standards
Drive Time
4h 4m
Distance
197.4 mi
318 km
Drive Score
9/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$32
one way
EV Charging
Unknown
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Manhattan, NY
Wikimedia Commons
Lisle, NY
Renan Tagliaferro
Manhattan, NY to Lisle, NY is 197.4 miles and takes about 4h 4m via I 81 and I 380, with a fuel budget near $32 and enough daylight to finish in a day. This highway-focused drive primarily utilizes major interstates as you head north out of the Northeast region and into its upper reaches. Expect a fairly direct journey with a significant portion on the interstate, making it a practical option for getting from point A to point B efficiently. If you're looking for a straightforward trip with minimal fuss, this route fits the bill, allowing you to cover the distance without extensive navigating.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
98.7 miles from Manhattan, NY
A natural place for your longest stop of the day , about 2h 7m into the drive .
| Road | Distance | Duration |
|---|---|---|
| I 81 | 73.8 mi | 1h 28m |
| Christopher Columbus Highway | 44.6 mi | 52m |
| I 380 | 27.7 mi | 30m |
| Keystone Shortway | 17.3 mi | 24m |
| US 46 | 10.8 mi | 12m |
| NJ 3 | 10.2 mi | 12m |
| Lincoln Tunnel | 3.4 mi | 6m |
| US 11 | 2.6 mi | 3m |
Step-by-step road directions between Manhattan, NY and Lisle, NY.
Start on 86th Street Transverse
Continue on West 86th Street
Turn left onto Columbus Avenue
Continue on 9th Avenue
Turn right onto West 41st Street
Turn left onto Galvin Avenue
Take the ramp
Merge onto NY 495
Take the exit
Keep slight left at fork
Merge onto NJ 3
Merge onto US 46
Take the exit
Continue on I 80W
Take the exit
Merge onto I 80
Keep slight left at fork onto I 80
Keep slight left at fork onto I 80
Take the exit
Continue on I 380
Merge onto I 81
Keep slight right at fork onto I 81
Keep slight left at fork onto I 81
Take the exit
Turn right onto NY 26
At end of road, turn left onto US 11; NY 26
Continue on US 11; NY 79
Arrive at destination
Given the relatively short 4-hour drive, you have plenty of flexibility for departure times. Leaving Manhattan in the morning should get you to Lisle with ample daylight remaining. With only one recommended stop and a modest fuel cost of $32, this trip is easy to manage. The longest stretch without an exit is over 70 miles on I 81, so plan your fuel and rest breaks accordingly before embarking on that segment. Consider a mid-morning departure to avoid the heaviest city traffic.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 43 miles or 58m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 98.7 miles or 2h 7m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 21m
Traffic, exits, and arrival timing usually matter more near Lisle, NY than in the middle of the route.
Open the route before leaving Manhattan, NY so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Manhattan, NY
This is one driving day of about 197.4 miles and 4h 4m.
Rest stops, refuel points, and overnight suggestions along this route.
Mid-route town
Meal stop
99 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 43 miles helps settle the day before fatigue starts building.
The midpoint is around 98.7 miles from Manhattan, NY, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before I 81 if your tank is already low. That segment runs about 73.8 miles.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
5 decision points cluster between mile 0.4 and 6.7 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
Turn left onto Columbus Avenue
Lane positioning matters here
Turn right onto West 41st Street
Lane positioning matters here
Take the ramp toward I 495 West: Lincoln Tunnel, New Jersey
Lane positioning matters here. Multiple destination signs - pick the right one
Take the exit toward NJ 3 West: Secaucus
Exit ramp - move to the correct lane early. Lane positioning matters here
Keep slight left at fork toward NJ 3 West: Clifton
Highway fork - watch signs carefully. Lane positioning matters here
Regular Gas
$32.49 one way
$64.99 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.52 | $35.14 | $70.27 |
| premium | $4.92 | $38.26 | $76.52 |
| diesel | $5.61 | $43.58 | $87.17 |
Estimated Tolls: $16.00
Toll estimates based on average 2024-2025 rates. EZ-Pass/SunPass discounts may lower the actual cost.
Estimated Trip Cost (one way, 1 person)
Fuel
$32
Tolls
$16
Meals
$25–$50
Total
$73–$98
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 69.1 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $21 in charging · 0 stops · 67% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 59.2 | 0 | $20.73 | $9.48 |
| Efficient EV | 49.4 | 0 | $17.27 | $7.90 |
| EV Truck/SUV | 79 | 0 | $27.64 | $12.63 |
Gas CO2
69 kg
EV CO2
23 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Late night in Manhattan on Sunday
Local time
3:29 AM
EDT
Current temp
49°F
Unavailable
Destination
Late night in Lisle on Sunday
Local time
3:29 AM
EDT
Current temp
34°F
Unavailable
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Worth a detour if your schedule allows.
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Park data from the National Park Service API. Alerts update every 2 hours.
This route is largely highway-focused, with 64% of the drive taking place on interstates like I 81 and I 380. You'll experience stretches of efficient, high-speed travel, including a notable segment of 73.8 miles on I 81 without needing to exit. The Christopher Columbus Highway also plays a role early in the journey. While primarily an interstate experience, the road provides a consistent and predictable driving environment for the majority of the trip.
This is a straightforward highway drive that stays mostly on I 81 and Christopher Columbus Highway. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 0.4 miles in near Columbus Avenue.
High effort - long or complex enough to need steady focus all day
Balances navigation complexity with total wheel time.
This is a demanding drive. With 23 significant decision points across 197.4 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 0.4 miles (Columbus Avenue): Lane positioning matters here; at 2.6 miles (West 41st Street): Lane positioning matters here; at 2.9 miles: Lane positioning matters here. Multiple destination signs - pick the right one.
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Manhattan, NY and Lisle, NY, road signs point toward Del Water Gap, Mahwah and Albany.
Del Water Gap
Mahwah
Albany
Founded 1624
Wall Street. Madison Avenue. 34th Street. Broadway. Times Square. Manhattan is so well known that even the names of its streets have become iconic and understood the world over. This long, thin island is only one of New York City's five boroughs, but it's Manhattan that has the concrete canyons and the inimitable skyline; Manhattan that has the world's brightest theater district; Manhattan that has Central Park, Rockefeller Center, the Empire State Building, and the Met; and Manhattan that includes iconic neighborhoods like Harlem, the Upper East Side, Times Square, and Greenwich Village. The rest of New York City has much to see and do, but it's Manhattan that represents the city—and sometimes the entire United States—to the world. You could spend a month on this tiny island and still not see all there is to see.
Top landmarks
City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).
Weekend Trip
Doable as a same-day drive at 4h 4m. Total distance: 197.4 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
4h 4m drive, comfortable solo distance.
Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, and NPS for national parks. See our methodology for refresh cadence and limitations.
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