This 126.3-mile drive from Laredo, TX to Mathis, TX is a straightforward journey that can easily be completed in a single day, taking approximately 2 hours and 27 minutes. The route primarily utilizes the Lloyd Bentsen Highway and FM 624, with a portion on US 59. Given its manageable length and estimated fuel cost of $19, it's an ideal day trip without the need for an overnight stop. You'll be traveling within the Great Plains region for the entirety of this Texas excursion. It offers a practical and efficient way to travel between these two South Texas locations.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Midpoint
63.1 miles from Laredo, TX
A natural place for your longest stop of the day
, about 1h 12m into the drive
.
Step-by-step road directions between Laredo, TX and Mathis, TX.
1
Start on Matamoros Street
0.3 mi·46 sec·Matamoros Street
2
Turn left onto San Dario Avenue
0.1 mi·11 sec·San Dario Avenue
3
Continue on San Dario Avenue
0.6 mi·1 min·San Dario Avenue
4
Turn right onto Park Street
0.3 mi·34 sec·Park Street
5
Continue on Clark Boulevard
3.0 mi·5 min·Clark Boulevard
6
Turn left onto Bob Bullock Loop
0.8 mi·1 min·Bob Bullock Loop
7
Take the ramp
231 ft·6 sec
8
Merge onto US 59
1.1 mi·1 min·East Saunders Street
9
Continue on US 59
58 mi·1 hr 1 min·Lloyd Bentsen Highway
10
Turn left onto US 59
23 mi·25 min·US 59
11
Turn right onto FM 624
16 mi·17 min·FM 624
12
Turn straight onto FM 624
11 mi·12 min·FM 624
13
Turn left onto TX 359
12 mi·17 min·TX 359
14
Turn left onto TX 359 Bus
0.6 mi·1 min·East San Patricio Avenue
15
Turn right onto TX 359 Bus
110 ft·2 sec·North Front Street
16
Arrive at destination
TX 359 Bus
Trip Plan
Given the 2 hour and 27-minute duration, you can comfortably depart Laredo anytime and arrive in Mathis with plenty of daylight remaining. There are no specific stops recommended on this route, so you can decide on your own pacing. Keep an eye on your fuel, especially during the longest stretch of 57.6 miles on the Lloyd Bentsen Highway, to avoid any unexpected delays. The $19 fuel cost is a good estimate, but it's always wise to have a little extra budgeted. This short drive offers flexibility, allowing you to leave when convenient.
Morning Departure
Leave by 9 AM and you'll arrive before lunch.
Evening Departure
Even a 4 PM departure gets you there before dark in summer.
You can normally do this drive in one day.
You may only need one short stretch break if traffic stays light.
The halfway point lands around 63.1 miles from Laredo, TX, or about 1h 12m into the drive.
The longest continuous stretch on this route runs about 57.6 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 28 miles or 34m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 63.1 miles or 1h 12m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 1h 57m
Traffic, exits, and arrival timing usually matter more near Mathis, TX than in the middle of the route.
Before You Leave
+
Open the route before leaving Laredo, TX so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Laredo, TX
This is one driving day of about 126.3 miles and 2h 27m.
Your first comfortable stop window is around 28 miles from Laredo, TX.
This route can stay practical as a one-day drive if traffic stays reasonable.
The longest stretch is on Lloyd Bentsen Highway for about 57.6 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 9
5 decision points cluster between mile 0.3 and 126.3 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
5
0.3 mi into trip|~0m in|San Dario Avenue
Turn left onto San Dario Avenue
Navigation decision point
4
1 mi into trip|~2m in|Park Street
Turn right onto Park Street
Navigation decision point
4
4.4 mi into trip|~8m in|Bob Bullock Loop
Turn left onto Bob Bullock Loop
Navigation decision point
4
114.1 mi into trip|~2h 9m in|TX 359
Turn left onto TX 359
Navigation decision point
4
126.3 mi into trip|~2h 27m in|TX 359 Bus / North Front Street
Turn right onto TX 359 Bus / North Front Street
Navigation decision point
Fuel & Cost
Regular Gas
$19.08 one way
$38.17 round trip
$3.84/gal25.4 MPG avg44 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.20
$20.89
$41.78
premium
$4.54
$22.55
$45.10
diesel
$5.61
$27.89
$55.77
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$19
Meals
$25–$50
Total
$44–$69
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 44.2 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $13 in charging
· 0 stops
· 66% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
37.9
0
$13.26
$6.06
Efficient EV
31.6
0
$11.05
$5.05
EV Truck/SUV
50.5
0
$17.68
$8.08
Gas CO2
44 kg
EV CO2
15 kg (66% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 15, 2026
Origin
Laredo, TX
Late night
in Laredo on Sunday
Local time
12:57 AM
CDT
Current temp
84°F
Unavailable
Live forecast
Destination
Mathis, TX
Late night
in Mathis on Sunday
Local time
12:57 AM
CDT
Current temp
66°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
18 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
2h 27m on the road
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
More Details
What kind of drive is this?
This drive presents a mixed profile, with about 49% of the journey on highways. You'll experience stretches on the Lloyd Bentsen Highway, including one uninterrupted segment of 57.6 miles, which offers a consistent pace. The inclusion of FM 624 and US 59 means you'll transition between different road types, offering some variety. It's not a monotonous interstate grind, but rather a blend of efficient highway driving and potentially more local road conditions as you progress towards Mathis.
49% highway, the rest on surface roads — varied driving throughout.
16 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 57.6 mi on Lloyd Bentsen Highway.
How Hard Is This Drive?
2/10
This route mixes highway mileage with some local-road sections near the start or finish. Navigation is very simple - set it and forget it for most of the drive. The trickiest moment comes around 0.3 miles in near San Dario Avenue.
Driving Effort2/10
Very easy - short and simple to drive
Balances navigation complexity with total wheel time.
The drive from Laredo, TX to Mathis, TX is easy. At 2h 27m with 49% highway, most drivers will find it relaxed and low-stress.
Where does it get tricky?
The main spots that need attention: at 0.3 miles (San Dario Avenue): Navigation decision point; at 1 miles (Park Street): Navigation decision point; at 4.4 miles (Bob Bullock Loop): Navigation decision point.
The longest stretch is about 57.6 miles on Lloyd Bentsen Highway. The full list of main roads is in the Roads section above.
Yes, with realistic expectations. Build in a stop roughly every 2 hours, have snacks and activities ready, and check the Nearby Places tabs for kid-friendly stops along the way.
The main spots that need attention: at 0.3 miles (San Dario Avenue): Navigation decision point; at 1 miles (Park Street): Navigation decision point; at 4.4 miles (Bob Bullock Loop): Navigation decision point.
Yes. A round trip is manageable in a single day if you plan a break at Mathis, TX before heading back.
