Jeffersonville, IN to Upland, IN is 183 miles and takes about 3h 26m via I 65 and I 69, with a fuel budget near $32 and enough daylight to finish in a day. This trip stays entirely within Indiana, traversing the Midwest region. Given its predominantly highway profile and manageable distance, it's a straightforward drive. You'll likely find it efficient for getting from point A to point B without extensive detours. Consider this route if you're looking for a quick connection between these two Indiana locations.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Break Rhythm
1 planned break
A short stop every 2 to 3 hours is enough for this drive.
Midpoint
91.5 miles from Jeffersonville, IN
A natural place for your longest stop of the day
, about 1h 40m into the drive
.
Main Roads
Road
Distance
Duration
I 65
101.9 mi
1h 50m
I 69
73.2 mi
1h 21m
South Emerson Avenue
2.5 mi
4m
East 500 South
2.4 mi
4m
County Road 500 South
0.7 mi
1m
East Court Avenue
0.4 mi
1m
US 35
0.3 mi
<1m
6th Street
0.3 mi
<1m
Longest stretch:
I 65
— 101.9 mi, about 1h 50m
Traffic on I-65
Hour-of-day weekday pattern from 48 FHWA count stations on your route.
Peak
4 PM
~3,790 veh/hr typical
Quietest
1 AM
~398 veh/hr
Peak-to-quiet ratio
9.5×
busier at peak than in the quiet hours
12a6anoon6p11p
Averaged across 50 weeks of 2023 FHWA Travel Monitoring Analysis System data. Weekday hours only (Mon–Fri).
Turn-by-Turn Driving Directions
Step-by-step road directions between Jeffersonville, IN and Upland, IN.
1
Start on Watt Street
257 ft·13 sec·Watt Street
2
Turn right onto East Court Avenue
0.4 mi·1 min·East Court Avenue
3
Turn slight right onto 6th Street
0.3 mi·45 sec·6th Street
4
Take the ramp
0.2 mi·28 sec
5
Merge onto I 65
102 mi·1 hr 50 min·I 65
6
Take the exit
0.4 mi·47 sec
Exit 103Toward Southport RoadUse the slight right lane.
7
Turn slight right
176 ft·4 sec
8
Turn straight onto East Southport Road
0.2 mi·26 sec·East Southport Road
9
Turn left onto South Emerson Avenue
2.5 mi·4 min·South Emerson Avenue
Use the left lane.
10
Take the ramp
0.5 mi·58 sec
11
Merge onto I 69; I 74; I 465
2.3 mi·2 min·I 69; I 74; I 465
12
Continue on I 69; I 465
12 mi·13 min·I 69; I 465
13
Keep slight right at fork onto I 69
4.2 mi·5 min·I 69
Exit 37Toward I 69 North: Fort Wayne
14
Keep slight left at fork onto I 69
55 mi·59 min·I 69
15
Take the exit onto US 35
0.3 mi·36 sec·US 35
Exit 259Toward US 35 North, SR 22: Gas City, Upland
16
Turn right onto SR 22
2.4 mi·4 min·East 500 South
17
Continue on SR 22
0.7 mi·1 min·County Road 500 South
18
Arrive at destination
SR 22
Trip Plan
With a 3h 26m estimated drive time, this route is easily completed in a single day, allowing for flexibility in your departure. Leaving in the morning will give you ample daylight to reach Upland, IN. Plan for one stop along the way to stretch your legs and refuel, as the longest stretch without a significant change in highway is over 100 miles. Given the highway-intensive nature, be mindful of the dense exits as you approach your destination. The $32 fuel cost is an estimate, so check current prices before you depart.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 91.5 miles from Jeffersonville, IN, or about 1h 40m into the drive.
The longest continuous stretch on this route runs about 101.9 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 40 miles or 44m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 91.5 miles or 1h 40m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 2h 48m
Traffic, exits, and arrival timing usually matter more near Upland, IN than in the middle of the route.
Before You Leave
+
Open the route before leaving Jeffersonville, IN so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Jeffersonville, IN
This is one driving day of about 183 miles and 3h 26m.
Your first comfortable stop window is around 40 miles from Jeffersonville, IN.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on I 65 for about 101.9 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 10
5 decision points cluster between mile 0 and 179.5 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
4
0 mi into trip|~0m in|East Court Avenue
Turn right onto East Court Avenue
Navigation decision point
7
102.8 mi into trip|~1h 52m in
Take the exit toward Southport Road
Exit ramp - move to the correct lane early. Lane positioning matters here
Use the slight right lane.
Exit 103
Toward Southport Road
6
103.4 mi into trip|~1h 54m in|South Emerson Avenue
Turn left onto South Emerson Avenue
Lane positioning matters here
Use the left lane.
6
120.4 mi into trip|~2h 15m in|I 69
Keep slight right at fork onto I 69 toward I 69 North: Fort Wayne
Highway fork - watch signs carefully
Exit 37
Toward I 69 North: Fort Wayne
6
179.5 mi into trip|~3h 20m in|US 35
Take the exit onto US 35 toward US 35 North, SR 22: Gas City, Upland
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Exit 259
Toward US 35 North, SR 22: Gas City, Upland
Fuel & Cost
Regular Gas
$30.43 one way
$60.85 round trip
$4.22/gal25.4 MPG avg64 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.60
$33.14
$66.28
premium
$5.18
$37.34
$74.68
diesel
$5.35
$38.55
$77.09
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$30
Meals
$25–$50
Total
$55–$80
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 64 kg one way.
Prices: EIA weekly data, 2026-06-01.
Driving Electric?
About $19 in charging
· 0 stops
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
54.9
0
$19.22
$8.78
Efficient EV
45.8
0
$16.01
$7.32
EV Truck/SUV
73.2
0
$25.62
$11.71
Gas CO2
64 kg
EV CO2
21 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Jun 1, 2026
Origin
Jeffersonville, IN
Afternoon
in Jeffersonville on Wednesday
Local time
4:09 PM
EDT
Current temp
82°F
Partly Sunny
NE 0 to 6 mph6% chanceLive forecast
Flood Warning
Flood Warning issued May 31 at 9:10PM EDT until June 2 at 6:00AM EDT by NWS Indianapolis IN
Flood Warning
Flood Warning issued May 31 at 9:10PM EDT until June 3 at 12:48PM EDT by NWS Indianapolis IN
Destination
Upland, IN
Afternoon
in Upland on Wednesday
Local time
4:09 PM
EDT
Current temp
75°F
Slight Chance Rain Showers
E 5 mph13% chanceLive forecast
Flood Warning
Flood Warning issued May 31 at 9:10PM EDT until June 2 at 6:00AM EDT by NWS Indianapolis IN
Flood Warning
Flood Warning issued May 31 at 9:10PM EDT until June 3 at 12:48PM EDT by NWS Indianapolis IN
84°F
Beech Grove, IN
92 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
7 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
3h 26m on the road
The weather snapshot is not static. If you are leaving later, give both cities one more quick forecast check before departure.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
More Details
What kind of drive is this?
This drive is almost entirely on the highway, with 96% of the 183 miles utilizing major interstates. You'll experience a longest stretch of 101.9 miles on I 65 before transitioning. The route is mostly highway, so expect a relatively fast pace. Surface roads, including South Emerson Avenue, make up the final portion of the trip, likely with more frequent exits and local traffic.
96% highway — fuel and pacing are the main things to plan.
18 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 101.9 mi on I 65.
How Hard Is This Drive?
5/10
This is a straightforward highway drive that stays mostly on I 65 and I 69. You will hit about 10 points where you need to pay attention to lane position or signs. The trickiest moment comes early in the drive near East Court Avenue.
Driving Effort5/10
Moderate - straightforward overall, but long enough or busy enough to require pacing
Balances navigation complexity with total wheel time.
This drive requires moderate attention. Across 183 miles you will encounter 10 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.
Where does it get tricky?
The main spots that need attention: near the start (East Court Avenue): Navigation decision point; at 102.8 miles: Exit ramp - move to the correct lane early. Lane positioning matters here; at 103.4 miles (South Emerson Avenue): Lane positioning matters here.
Jeffersonville, often called "Jeff" by locals, is the county seat of Clark County in Southern Indiana, on the opposite side of the Ohio River from Louisville, Kentucky and connected to Louisville by the Kennedy, Lincoln, and Lewis and Clark Bridges. It has a population of 48,000 (2019).
Top landmarks
•George Rogers Clark Memorial Bridge — crossing of the Ohio River between Louisville, Kentucky, and Jeffersonville, Ind...
•Spring Street Freight House — constructed in 1925
Doable as a same-day drive at 3h 26m. Total distance: 183 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
3h 26m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (96%). Some complex stretches to watch for.
Frequently Asked Questions
The longest stretch is about 101.9 miles on I 65. The full list of main roads is in the Roads section above.
Yes — we found about 14 rest areas or service plazas within a short detour of the route (from OpenStreetMap). See the Rest Stops tab under Nearby Places for locations and mile markers. Plan to stretch, use the bathroom, and top off fluids every 2–3 hours on longer drives.
Yes, with realistic expectations. Build in a stop roughly every 2 hours, have snacks and activities ready, and check the Nearby Places tabs for kid-friendly stops along the way.
The main spots that need attention: near the start (East Court Avenue): Navigation decision point; at 102.8 miles: Exit ramp - move to the correct lane early. Lane positioning matters here; at 103.4 miles (South Emerson Avenue): Lane positioning matters here.
Possible but tiring. At 3.4 hours each way, an in-and-out day trip would put you behind the wheel for 6.9 hours — manageable with a long break at Upland, IN, but most travelers stay overnight.
