Traveling from Greenup to Hopkinsville covers 328.1 miles across the state of Kentucky. You should anticipate a total drive time of approximately 6 hours and 4 minutes, making this a manageable but significant day trip if you get an early start. Your route primarily utilizes Seaton Avenue, Industrial Parkway, and I-64 West to navigate between the two points. Budgeting about $50 for fuel will cover your transit costs for the journey. Because the trip spans the Southeast region, you can expect a fairly consistent regional atmosphere throughout the drive. While it is possible to complete the trip in one day, be prepared for a full day of travel on the road.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
164 miles from Greenup, KY
A natural place for your longest stop of the day
, about 3h 5m into the drive
.
Main Roads
Road
Distance
Duration
I 64
98.9 mi
1h 47m
Western Kentucky Parkway
98 mi
1h 45m
Bluegrass Parkway
70.6 mi
1h 15m
I 169
24.7 mi
26m
Industrial Parkway
13.9 mi
15m
West New Circle Road
5.8 mi
8m
Versailles Road
4.5 mi
6m
Seaton Avenue
2.3 mi
3m
Longest stretch:
I 64
— 98.9 mi, about 1h 47m
Turn-by-Turn Driving Directions
Step-by-step road directions between Greenup, KY and Hopkinsville, KY.
1
Start on KY 2541
0.5 mi·54 sec·Walnut Street
2
Turn left onto US 23
2.3 mi·3 min·Seaton Avenue
3
Turn right onto KY 67
14 mi·15 min·Industrial Parkway
4
Keep slight right at fork
0.3 mi·35 sec
5
Merge onto I 64
96 mi·1 hr 43 min·I 64
6
Keep slight right at fork onto I 64
2.4 mi·3 min·I 64
Toward I 64 West, I 75 North: Louisville, Cincinnati
7
Take the exit
0.4 mi·1 min
Exit 113Toward US 27, US 68: Paris, LexingtonUse the straight / slight right lanes.
8
Turn right onto US 27; US 68
1.2 mi·2 min·North Broadway
9
Turn right onto US KY4
5.8 mi·8 min·West New Circle Road
Use the straight / slight right lanes.
10
Take the exit
0.3 mi·44 sec
Exit 5BToward US 60 West: VersaillesUse the slight right lane.
11
Merge onto US 60
4.5 mi·6 min·Versailles Road
Use the left lane.
12
Continue on US 60
1.3 mi·1 min·Lexington Road
13
Take the exit
0.7 mi·1 min
Toward Elizabethtown
14
Continue on Bluegrass Parkway
71 mi·1 hr 15 min·Bluegrass Parkway
15
Keep slight left at fork
0.9 mi·1 min
16
Merge onto I 65
1.2 mi·1 min·I 65
17
Take the exit
0.2 mi·26 sec
Exit 91C-AToward KY 61 South: Elizabethtown, Paducah, Western Kentucky ParkwayUse the straight / slight right lanes.
18
Keep slight right at fork
0.2 mi·31 sec
Exit 91C-BToward US 31W: Elizabethtown, Paducah, Western Kentucky Parkway West
19
Keep slight left at fork
0.3 mi·41 sec
Toward Paducah, Elizabethtown
20
Merge onto Western Kentucky Parkway
98 mi·1 hr 45 min·Western Kentucky Parkway
21
Take the exit
0.4 mi·45 sec
Exit 38BToward I 169 South: HopkinsvilleUse the slight right lane.
22
Merge onto I 169
281 ft·3 sec·I 169
23
Continue on I 169
25 mi·26 min·I 169
Exit 106A
24
Take the exit
0.2 mi·30 sec
Exit 9Toward US 68, KY 80
25
Keep slight right at fork
184 ft·4 sec
Exit 9Toward US 68, KY 80
26
Turn straight onto US 68; KY 80
0.3 mi·29 sec·McLean Avenue
27
Turn right onto US 41; KY 109
0.7 mi·1 min·East 9th Street
28
Turn left onto Bethel Street
301 ft·13 sec·Bethel Street
29
Arrive at destination
Bethel Street
Trip Plan
Pacing is key for this 328.1-mile journey, so plan for at least one dedicated stop to stretch your legs and refresh. Since the route is turn-heavy, leave early in the morning to ensure you have maximum daylight for the more technical road sections. Keep your $50 fuel budget in mind when planning your refueling stops along the way to avoid running low on local stretches. Because you are navigating non-highway roads, stay alert for changing speed limits and local traffic patterns that might slow your progress. Use the flexibility of this one-day itinerary to adjust your departure time based on peak local traffic hours to ensure a smoother experience.
Morning Departure
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Evening Departure
This is a long drive — plan for a morning departure or consider splitting it into two days.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 164 miles from Greenup, KY, or about 3h 5m into the drive.
The longest continuous stretch on this route runs about 98.9 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 72 miles or 1h 19m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 164 miles or 3h 5m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 4h 59m
Traffic, exits, and arrival timing usually matter more near Hopkinsville, KY than in the middle of the route.
Before You Leave
+
Open the route before leaving Greenup, KY so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Greenup, KY
This is one driving day of about 328.1 miles and 6h 4m.
Your first comfortable stop window is around 72 miles from Greenup, KY.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on I 64 for about 98.9 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 22
5 decision points cluster between mile 115.9 and 327 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
8
115.9 mi into trip|~2h 7m in
Take the exit toward US 27, US 68: Paris, Lexington
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / slight right lanes.
Exit 113
Toward US 27, US 68: Paris, Lexington
7
123.3 mi into trip|~2h 18m in
Take the exit toward US 60 West: Versailles
Exit ramp - move to the correct lane early. Lane positioning matters here
Use the slight right lane.
Exit 5B
Toward US 60 West: Versailles
8
202.9 mi into trip|~3h 47m in
Take the exit toward KY 61 South: Elizabethtown, Paducah, Western Kentucky Parkway
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / slight right lanes.
Exit 91C-A
Toward KY 61 South: Elizabethtown, Paducah, Wes...
8
203.1 mi into trip|~3h 48m in
Keep slight right at fork toward US 31W: Elizabethtown, Paducah, Western Kentucky Parkway West
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Exit 91C-B
Toward US 31W: Elizabethtown, Paducah, Western...
8
327 mi into trip|~6h 2m in
Keep slight right at fork toward US 68, KY 80
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Exit 9
Toward US 68, KY 80
Fuel & Cost
Regular Gas
$51.29 one way
$102.59 round trip
$3.97/gal25.4 MPG avg115 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.36
$56.32
$112.64
premium
$4.89
$63.14
$126.28
diesel
$5.61
$72.44
$144.88
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$51
Meals
$25–$50
Total
$76–$101
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 114.8 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $34 in charging
· 1 stop
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
98.4
1
$34.45
$15.75
Efficient EV
82
0
$28.71
$13.12
EV Truck/SUV
131.2
1
$45.93
$21.00
Gas CO2
115 kg
EV CO2
38 kg (67% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 15, 2026
Origin
Greenup, KY
Night
in Greenup on Saturday
Local time
9:22 PM
EDT
Current temp
76°F
Unavailable
Live forecast
Destination
Hopkinsville, KY
Evening
in Hopkinsville on Saturday
Local time
8:22 PM
CDT
Current temp
54°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
1 hour earlier
The destination clock does not match departure time, so double-check hotel check-in windows and late arrival plans.
Temperature spread
22 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
6h 4m on the road
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
Abraham Lincoln Birthplace National Historical Park
National Historical Park
For over a century people from around the world have come to rural Central Kentucky to honor the humble beginnings of our 16th president, Abraham Lincoln. His early life on Kentucky's frontier shaped...
11 mi from route
~28 min detour
Free
near mile 192.3
The US Army established Camp Nelson as a fortified supply depot in April 1863. Over the next 3 years, the site evolved into a massive recruitment and training center for United States Colored Troops a...
17 mi from route
~43 min detour
Free
near mile 124.4
Rolling hills, deep river valleys, and the world's longest known cave system. Mammoth Cave National Park is home to thousands of years of human history and a rich diversity of plant and animal life, e...
21 mi from route
~52 min detour
Free
near mile 226.3
Park data from the National Park Service API. Alerts update every 2 hours.
More Details
What kind of drive is this?
Expect a turn-heavy local drive that demands your full attention behind the wheel. Unlike a monotonous interstate slog, this route requires navigating local roads like Seaton Avenue and Industrial Parkway before transitioning onto the highway system. With a 0% highway share, the character of this trip is defined by technical turns rather than long, high-speed stretches. You will experience a more intimate look at the local landscape as you maneuver through various turns rather than cruising on a straight path. It is a drive that keeps you engaged, as the infrastructure relies heavily on local thoroughfares to connect your start and end points.
94% highway — fuel and pacing are the main things to plan.
29 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 98.9 mi on I 64.
How Hard Is This Drive?
10/10
This is a straightforward highway drive that stays mostly on I 64 and Western Kentucky Parkway. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 115.9 miles in.
Driving Effort10/10
High effort - long or complex enough to need steady focus all day
Balances navigation complexity with total wheel time.
This is a demanding drive. With 22 significant decision points across 328.1 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 115.9 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 123.3 miles: Exit ramp - move to the correct lane early. Lane positioning matters here; at 202.9 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Greenup, KY and Hopkinsville, KY, road signs point toward Cincinnati, Lexington, Elizabethtown, Paducah and Western Kentucky Parkway West.
Doable as a same-day drive at 6h 4m. Total distance: 328.1 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
6h 4m drive, plan rest stops for pacing.
Frequently Asked Questions
The longest stretch is about 98.9 miles on I 64. The full list of main roads is in the Roads section above.
We did not find dedicated rest areas on this route. For a drive this long, plan bathroom and stretch breaks around gas stations, fast-food stops, or small-town downtowns — check the Nearby Places section for options.
It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Hopkinsville, KY before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. Dedicated rest areas are limited, so plan gas or food stops as your bathroom breaks.
The main spots that need attention: at 115.9 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 123.3 miles: Exit ramp - move to the correct lane early. Lane positioning matters here; at 202.9 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Yes — Abraham Lincoln Birthplace National Historical Park, Camp Nelson National Monument and Mammoth Cave National Park. See the National Parks section for detour distances and tips on detours.
Not recommended in a single day. At 6.1 hours each way, a round trip means 12.2 hours of driving — that is an unsafe level of fatigue for most drivers. Plan at least one night at Hopkinsville, KY before the return drive.
