This 106-mile journey from Greene to Lafayette, Indiana, is a manageable 2-hour and 35-minute drive, making it an ideal day trip. You'll spend about 28% of your time on highways, with the remainder on local roads. The estimated fuel cost for this Midwest excursion is around $17. With only one recommended stop, this route offers a straightforward travel experience. It’s a straightforward drive that gets you from point A to point B efficiently within the same state.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Break Rhythm
1 planned break
A short stop every 2 to 3 hours is enough for this drive.
Midpoint
53 miles from Greene, IN
A natural place for your longest stop of the day
, about 1h 18m into the drive
.
Main Roads
Road
Distance
Duration
SR 67
15.1 mi
17m
I 65
13.7 mi
15m
East County Road 600 North
10 mi
14m
East 600 North
10 mi
14m
West 200 South
9.9 mi
15m
County Road 100 South
7.8 mi
11m
Walnut Avenue
7.3 mi
10m
1200 North
6.1 mi
9m
Longest stretch:
SR 67
— 15.1 mi, about 17m
Turn-by-Turn Driving Directions
Step-by-step road directions between Greene, IN and Lafayette, IN.
1
Start on West 200 South
413 ft·18 sec·West 200 South
2
Turn right onto South Como Road
1.8 mi·6 min·South Como Road
3
Turn right onto SR 67
15 mi·17 min·SR 67
4
Turn right onto SR 28
2.7 mi·4 min·East County Road 600 North
5
Continue on US 35; SR 28
10.0 mi·14 min·East 600 North
6
Continue on US 35; SR 28
7.3 mi·10 min·East County Road 600 North
7
Continue on SR 28
6.1 mi·9 min·1200 North
8
Continue on SR 28
2.7 mi·4 min·Main Street
9
Continue on SR 28
1.5 mi·2 min·East 150 South
10
Continue on SR 28
3.2 mi·4 min·State Road 28
11
Continue on SR 28
4.0 mi·6 min·East 150 South
12
Continue on SR 28
1.5 mi·2 min·East Jefferson Street
Use the straight / right lanes.
13
Continue on West Old State Road 28
0.7 mi·1 min·West Old State Road 28
14
Continue on West 200 South
3.4 mi·5 min·West 200 South
15
Enter roundabout onto West 200 South
93 ft·1 sec·West 200 South
16
Continue on West 200 South
0.1 mi·12 sec·West 200 South
17
Enter roundabout onto SR 28
136 ft·2 sec·West 200 South
18
Continue on SR 28
0.1 mi·13 sec·West 200 South
19
Enter roundabout onto SR 28
160 ft·2 sec·West 200 South
20
Continue on SR 28
6.1 mi·9 min·West 200 South
21
Continue on SR 28
7.8 mi·11 min·County Road 100 South
22
At end of road, turn right onto US 421; SR 28
0.5 mi·50 sec·US 421; SR 28
23
Turn left onto US 421; SR 28
2.0 mi·2 min·East County Road 50 South
24
Continue on US 421; SR 28
3.4 mi·5 min·East Wabash Street
25
Turn slight right
215 ft·4 sec
26
Turn slight right onto US 421; SR 28
179 ft·8 sec·South Hoke Avenue
27
Turn left onto US 421; SR 28
1.3 mi·1 min·East Walnut Street
28
Turn straight onto SR 28
7.3 mi·10 min·Walnut Avenue
29
Take the ramp
0.3 mi·36 sec
30
Merge onto I 65
14 mi·15 min·I 65
31
Take the exit
0.2 mi·29 sec
Exit 172Toward SR 26: Lafayette, Rossville
32
Turn left onto SR 26
0.2 mi·23 sec·SR 26
33
Continue on South Street
2.7 mi·5 min·South Street
34
Turn slight left onto Jackson Street
0.1 mi·30 sec·Jackson Street
35
Turn right
178 ft·13 sec
36
Arrive at destination
Trip Plan
Given the relatively short duration of 2 hours and 35 minutes, this trip is perfectly suited for a single day. You can easily depart in the morning and arrive in Lafayette by midday. Consider leaving Greene a little later in the morning to avoid any potential early rush hour traffic, though with only 28% highway share, delays are generally minimal. The single recommended stop is a good point to stretch your legs, but don't feel obligated if you're making good time. Keep an eye out for signage as you transition between SR 67 and I-65 to ensure you're on the correct path.
Morning Departure
Leave by 9 AM and you'll arrive before lunch.
Evening Departure
Even a 4 PM departure gets you there before dark in summer.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 53 miles from Greene, IN, or about 1h 18m into the drive.
The longest continuous stretch on this route runs about 15.1 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 23 miles or 33m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 53 miles or 1h 18m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 2h 9m
Traffic, exits, and arrival timing usually matter more near Lafayette, IN than in the middle of the route.
Before You Leave
+
Open the route before leaving Greene, IN so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Greene, IN
This is one driving day of about 106 miles and 2h 35m.
Your first comfortable stop window is around 23 miles from Greene, IN.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on SR 67 for about 15.1 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 15
5 decision points cluster between mile 60.1 and 105.9 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
5
60.1 mi into trip|~1h 28m in|SR 28 / West 200 South
Enter roundabout onto SR 28 / West 200 South
Roundabout - know your exit number before entering
5
60.3 mi into trip|~1h 29m in|SR 28 / West 200 South
Enter roundabout onto SR 28 / West 200 South
Roundabout - know your exit number before entering
5
74.2 mi into trip|~1h 49m in|US 421; SR 28
At end of road, turn right onto US 421; SR 28
Navigation decision point
6
102.7 mi into trip|~2h 28m in
Take the exit toward SR 26: Lafayette, Rossville
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Exit 172
Toward SR 26: Lafayette, Rossville
5
105.9 mi into trip|~2h 34m in
Turn right
Navigation decision point
Fuel & Cost
Regular Gas
$16.57 one way
$33.14 round trip
$3.97/gal25.4 MPG avg37 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.36
$18.20
$36.39
premium
$4.89
$20.40
$40.80
diesel
$5.61
$23.40
$46.81
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$17
Meals
$25–$50
Total
$42–$67
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 37.1 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $11 in charging
· 0 stops
· 68% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
31.8
0
$11.13
$5.09
Efficient EV
26.5
0
$9.27
$4.24
EV Truck/SUV
42.4
0
$14.84
$6.78
Gas CO2
37 kg
EV CO2
12 kg (68% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 13, 2026
Origin
Greene, IN
Morning
in Greene on Sunday
Local time
7:50 AM
EDT
Current temp
73°F
Unavailable
Live forecast
Destination
Lafayette, IN
Morning
in Lafayette on Sunday
Local time
7:50 AM
EDT
Current temp
65°F
Chance Showers And Thunderstorms
SW 14 to 20 mph63% chanceLive forecast
Special Weather Statement
Special Weather Statement issued April 13 at 3:33AM EDT by NWS Northern Indiana
Special Weather Statement
Special Weather Statement issued April 13 at 3:33AM EDT by NWS Wilmington OH
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
8 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
2h 35m on the road
The weather snapshot is not static. If you are leaving later, give both cities one more quick forecast check before departure.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
More Details
What kind of drive is this?
Expect a turn-heavy local drive for much of this route. While you'll encounter some highway stretches, including I-65, the majority of your time will be spent navigating state roads and county routes. The longest uninterrupted stretch you'll experience is about 15.1 miles on SR 67. This means you'll be adjusting your speed and turning more frequently than on a pure interstate cruise, offering a more engaging driving experience.
Only 28% highway — the rest is turn-by-turn surface driving.
36 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 15.1 mi on SR 67.
How Hard Is This Drive?
3/10
Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. There are only a few real navigation decisions along the way. The trickiest moment comes around 60.1 miles in near SR 28 / West 200 South.
Driving Effort3/10
Easy - simple navigation with a manageable amount of wheel time
Balances navigation complexity with total wheel time.
This is a straightforward 2h 35m drive. You will face about 15 decision points, but nothing that requires special attention if you follow navigation.
Where does it get tricky?
The main spots that need attention: at 60.1 miles (SR 28 / West 200 South): Roundabout - know your exit number before entering; at 60.3 miles (SR 28 / West 200 South): Roundabout - know your exit number before entering; at 74.2 miles (US 421; SR 28): Navigation decision point.
Elevation Profile
Mostly flat terrain
960 ft682 ft
Total Climb
143 ft
Total Descent
360 ft
Highest Point
960 ft
~7.6 mi in
Elevation Range
278 ft
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 2h 35m. Total distance: 106 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
The longest stretch is about 15.1 miles on SR 67. The full list of main roads is in the Roads section above.
Yes, with realistic expectations. Build in a stop roughly every 2 hours, have snacks and activities ready, and check the Nearby Places tabs for kid-friendly stops along the way.
The main spots that need attention: at 60.1 miles (SR 28 / West 200 South): Roundabout - know your exit number before entering; at 60.3 miles (SR 28 / West 200 South): Roundabout - know your exit number before entering; at 74.2 miles (US 421; SR 28): Navigation decision point.
Yes. A round trip is manageable in a single day if you plan a break at Lafayette, IN before heading back.
