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Trip from Gainesville, FL to Lady Lake, FL

Compiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Apr 19, 2026 · Editorial standards

Drive Time

1h 24m

Distance

65.2 mi

105 km

Drive Score

8/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$10

one way

EV Charging

Good

8 stations

Best Time to Leave

Save up to 19 min
4 AM
1h 18m ★
6 AM
1h 24m
8 AM
1h 37m
10 AM
1h 29m
12 PM
1h 28m
3 PM
1h 30m
5 PM
1h 37m
8 PM
1h 20m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

town in Lake County, Florida, United States

Lady Lake, FL

Wikimedia Commons

Trip Overview

Gainesville to Lady Lake is 65.2 miles and takes about 1 hour 24 minutes via I 75, US 27, and US 441, with a fuel budget near $10 and enough daylight to finish in a day. This drive stays within Florida, making it a straightforward, same-day trip. You'll mostly be on major highways, so expect a relatively quick journey. It's a practical route if you're looking for efficient travel between these two points without extensive detours. Consider this trip for its simplicity and directness.

Main Roads

Road Distance Duration
I 75 33.8 mi 36m
US 27 10 mi 15m
US 441 8 mi 9m
Southwest 135th Street 5.7 mi 8m
South Main Street 2.5 mi 5m
Southeast 132nd Street Road 2.5 mi 3m
Southeast County Road 234 1.4 mi 2m
Southwest Williston Road 0.5 mi <1m
Longest stretch: I 75 — 33.8 mi, about 36m

Turn-by-Turn Driving Directions

Step-by-step road directions between Gainesville, FL and Lady Lake, FL.

1

Start on CR 329

0.5 mi · 1 min · South Main Street
Use the straight / right lanes.
2

Enter roundabout onto CR 329

148 ft · 3 sec · South Main Street
3

Continue on CR 329

0.3 mi · 32 sec · South Main Street
4

Enter roundabout onto CR 329

57 ft · 1 sec · South Main Street
5

Continue on CR 329

1.6 mi · 2 min · South Main Street
6

Turn right onto FL 331

0.5 mi · 54 sec · Southwest Williston Road
7

Turn left onto South Main Street

0.2 mi · 23 sec · South Main Street
Use the left lane.
8

Turn straight onto US 441

0.4 mi · 33 sec · US 441
Use the straight / left lanes.
9

Continue on US 441

7.0 mi · 8 min · US 441
Use the straight lane.
10

Continue on US 441

0.6 mi · 47 sec · US 441
Use the straight lane.
11

Turn right onto CR 234

1.4 mi · 2 min · Southeast County Road 234
Use the right lane.
12

Take the ramp

0.2 mi · 27 sec
Toward I 75 South: Tampa
13

Merge onto I 75

34 mi · 36 min · I 75
14

Take the exit

0.3 mi · 37 sec
Exit 341 Toward CR 484: Belleview, Dunnellon
15

Turn left onto CR 484

5.7 mi · 8 min · Southwest 135th Street
Use the straight lane.
16

Continue on Southeast 132nd Street Road

2.5 mi · 3 min · Southeast 132nd Street Road
Use the left / straight lanes.
17

Turn right onto US 27; US 441

10 mi · 15 min · US 27; US 441
18

Turn right onto CR 466

0.1 mi · 18 sec · CR 466
19

Continue on CR 466

0.1 mi · 24 sec · CR 466
20

Arrive at destination

CR 466

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Downtown Ocala, FL, FL

Mid-route town

Meal stop

Ocala, FL

33 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

Williston, FL

Fuel and coffee

A short stop after about 14 miles helps settle the day before fatigue starts building.

Ocala, FL

Meal break

The midpoint is around 32.6 miles from Gainesville, FL, which is a good place for a longer meal and fuel stop.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Heads-up: tricky spots

5 of 12

5 decision points cluster between mile 0.5 and 46.3 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.

5
0.5 mi into trip | ~1m in | CR 329 / South Main Street

Enter roundabout onto CR 329 / South Main Street

Roundabout - know your exit number before entering

5
0.8 mi into trip | ~1m in | CR 329 / South Main Street

Enter roundabout onto CR 329 / South Main Street

Roundabout - know your exit number before entering

5
2.9 mi into trip | ~5m in | South Main Street

Turn left onto South Main Street

Lane positioning matters here

Use the left lane.
5
11 mi into trip | ~15m in | CR 234 / Southeast County Road 234

Turn right onto CR 234 / Southeast County Road 234

Lane positioning matters here

Use the right lane.
6
46.3 mi into trip | ~54m in

Take the exit toward CR 484: Belleview, Dunnellon

Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one

Exit 341 Toward CR 484: Belleview, Dunnellon

Fuel & Cost

Regular Gas

$10.38 one way

$20.76 round trip

$4.04/gal 25.4 MPG avg 23 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.40 $11.29 $22.58
premium $4.72 $12.12 $24.25
diesel $5.61 $14.40 $28.79

No toll roads detected on this route.

Drive Cost (one way)

Fuel

$10

Estimated CO2 emission: 22.8 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $7 in charging · 0 stops · 65% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 19.6 0 $6.85 $3.13
Efficient EV 16.3 0 $5.71 $2.61
EV Truck/SUV 26.1 0 $9.13 $4.17

Gas CO2

23 kg

EV CO2

8 kg (65% less)

This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Apr 15, 2026

Origin

Gainesville, FL

Late night in Gainesville on Sunday

Local time

3:50 AM

EDT

Current temp

81°F

Unavailable

Live forecast

Destination

Lady Lake, FL

Late night in Lady Lake on Sunday

Local time

3:50 AM

EDT

Current temp

59°F

Unavailable

Live forecast

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

22 degrees cooler at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

1h 24m on the road

Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

What kind of drive is this?

This is a highway-focused drive, with about 80% of your journey on major roads like I 75. You'll encounter the longest uninterrupted stretch, 33.8 miles, on I 75. While much of the drive is on the interstate, you'll also navigate sections of US 27 and US 441, which may offer slightly different scenery and traffic patterns. The overall feel is one of consistent forward momentum, ideal for those who prefer covering ground efficiently.

80% highway — fuel and pacing are the main things to plan.
20 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 33.8 mi on I 75.

How Hard Is This Drive?

5/10

This is a straightforward highway drive that stays mostly on I 75 and US 27. You will hit about 12 points where you need to pay attention to lane position or signs. The trickiest moment comes around 0.5 miles in near CR 329 / South Main Street.

Driving Effort 5/10

Moderate - straightforward overall, but long enough or busy enough to require pacing

Balances navigation complexity with total wheel time.

This drive requires moderate attention. Across 65.2 miles you will encounter 12 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.

Where does it get tricky?

The main spots that need attention: at 0.5 miles (CR 329 / South Main Street): Roundabout - know your exit number before entering; at 0.8 miles (CR 329 / South Main Street): Roundabout - know your exit number before entering; at 2.9 miles (South Main Street): Lane positioning matters here.

Towns Mentioned on Route Signs

Based on OSRM destination-sign hints, not a full list of every settlement the road passes.

Between Gainesville, FL and Lady Lake, FL, road signs point toward Cr 484: Belleview and Dunnellon.

Cr 484: Belleview

46.3 mi in | ~54m

Dunnellon

46.3 mi in | ~54m

About the Cities

Starting in Gainesville, FL

Full guide →

Gainesville is in North Central Florida. It is home to the University of Florida, and Santa Fe College.

City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).

Who Is This Route For?

Weekend Trip

Doable as a same-day drive at 1h 24m. Total distance: 65.2 miles.

Family Friendly

Moderate complexity with 0 natural rest stops along the way.

Solo Traveler

1h 24m drive, comfortable solo distance.

EV Driver

0 DC fast chargers along the route. Coverage: unknown.

First-Time Driver

Mostly highway driving (80%). Some complex stretches to watch for.

Frequently Asked Questions

The longest stretch is about 33.8 miles on I 75. The full list of main roads is in the Roads section above.

Yes. At under 2 hours behind the wheel, this works well for families — plan one quick stop if you have younger kids.

The main spots that need attention: at 0.5 miles (CR 329 / South Main Street): Roundabout - know your exit number before entering; at 0.8 miles (CR 329 / South Main Street): Roundabout - know your exit number before entering; at 2.9 miles (South Main Street): Lane positioning matters here.

Yes. A round trip is manageable in a single day if you plan a break at Lady Lake, FL before heading back.

How this page is built

Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, and EIA for fuel prices. See our methodology for refresh cadence and limitations.

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