If you are planning a trip from Endicott to Syracuse, you are looking at a straightforward 75.4-mile journey through the Northeast. Expect to spend about 1 hour and 37 minutes behind the wheel, making this an ideal candidate for a one-day trip that requires no overnight stops. Budgeting approximately $12 for fuel should cover your travel costs comfortably. Since both cities are located within New York, you will remain in the same region for the duration of the drive. This route is efficient and practical, serving as a reliable connection between the two areas without the need for complex multi-day planning.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Midpoint
37.7 miles from Endicott, NY
A natural place for your longest stop of the day
, about 52m into the drive
.
Main Roads
Road
Distance
Duration
I 81
52.7 mi
1h 1m
State Highway 26
10.8 mi
15m
Union Center-Maine Highway
7.3 mi
12m
US 11
1 mi
1m
East Main Street
0.8 mi
1m
Nanticoke Avenue
0.7 mi
1m
I-81
0.4 mi
<1m
Almond Street
0.3 mi
<1m
Longest stretch:
I 81
— 52.7 mi, about 1h 1m
Turn-by-Turn Driving Directions
Step-by-step road directions between Endicott, NY and Syracuse, NY.
1
Start on Park Street
225 ft·15 sec·Park Street
2
Turn left onto Jefferson Avenue
239 ft·10 sec·Jefferson Avenue
3
Turn right onto NY 17C; NY 26
0.8 mi·1 min·East Main Street
4
Turn right onto NY 26
0.7 mi·1 min·Nanticoke Avenue
5
Continue on NY 26
7.1 mi·11 min·Union Center-Maine Highway
6
Continue on NY 26
0.2 mi·13 sec·Union Center-Maine Highway
7
Continue on NY 26
4.6 mi·6 min·State Highway 26
8
Continue on NY 26
0.3 mi·28 sec·Union Center Maine Highway
9
Continue on NY 26
6.3 mi·9 min·State Highway 26
10
At end of road, turn left onto US 11; NY 26
0.1 mi·9 sec·US 11; NY 26
11
Continue on US 11; NY 79
0.9 mi·1 min·US 11; NY 79
12
Take the exit
0.4 mi·46 sec
Toward I 81 North
13
Merge onto I 81
51 mi·58 min·I 81
Use the straight / slight right lanes.
14
Keep slight left at fork onto I 81
0.2 mi·17 sec·I 81
Toward SyracuseUse the straight lane.
15
Continue on I-81
0.4 mi·26 sec·I-81
16
Continue on I 81
1.9 mi·2 min·I 81
17
Take the exit
0.3 mi·36 sec
Toward Adams Street, Harrison StreetUse the slight right lane.
18
Continue on Almond Street
0.3 mi·38 sec·Almond Street
Use the left / slight left / straight / right lanes.
19
Turn left onto NY 92
0.3 mi·36 sec·East Genesee Street
20
At end of road, turn right onto US 11
10 ft·0 sec·South State Street
21
Arrive at destination
US 11
Trip Plan
Because this drive is relatively short, you have plenty of flexibility regarding your departure time. Since the trip is only 1 hour and 37 minutes, you can easily complete it in one go without needing dedicated rest stops for fatigue. Keep an eye on your fuel gauge before setting out, as the $12 estimated cost is based on typical consumption for a 75.4-mile distance. If you prefer a smoother ride, try to avoid peak commuting hours when the I-81 corridor might see increased volume. Use the ease of this quick transit to plan your arrival in Syracuse with precision, knowing you won't be bogged down by a long, exhausting haul.
Morning Departure
Leave by 9 AM and you'll arrive before lunch.
Evening Departure
Even a 4 PM departure gets you there before dark in summer.
You can normally do this drive in one day.
You may only need one short stretch break if traffic stays light.
The halfway point lands around 37.7 miles from Endicott, NY, or about 52m into the drive.
The longest continuous stretch on this route runs about 52.7 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 17 miles or 27m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 37.7 miles or 52m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 1h 23m
Traffic, exits, and arrival timing usually matter more near Syracuse, NY than in the middle of the route.
Before You Leave
+
Open the route before leaving Endicott, NY so your first major turns are already loaded.
Day 1
Settle into the route from Endicott, NY
This is one driving day of about 75.4 miles and 1h 37m.
Your first comfortable stop window is around 17 miles from Endicott, NY.
This route can stay practical as a one-day drive if traffic stays reasonable.
The longest stretch is on I 81 for about 52.7 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 10
5 decision points cluster between mile 0 and 75.4 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
5
0 mi into trip|~0m in|Jefferson Avenue
Turn left onto Jefferson Avenue
Navigation decision point
5
20 mi into trip|~31m in|US 11; NY 26
At end of road, turn left onto US 11; NY 26
Navigation decision point
7
71.9 mi into trip|~1h 32m in|I 81
Keep slight left at fork onto I 81 toward Syracuse
Highway fork - watch signs carefully. Lane positioning matters here
Use the straight lane.
Toward Syracuse
7
74.5 mi into trip|~1h 35m in
Take the exit toward Adams Street, Harrison Street
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight right lane.
Toward Adams Street, Harrison Street
6
75.4 mi into trip|~1h 37m in|US 11 / South State Street
At end of road, turn right onto US 11 / South State Street
Complex interchange - multiple decisions in a short stretch
Fuel & Cost
Regular Gas
$12.41 one way
$24.82 round trip
$4.18/gal25.4 MPG avg26 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.52
$13.42
$26.84
premium
$4.92
$14.61
$29.23
diesel
$5.61
$16.65
$33.29
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$12
Meals
$25–$50
Total
$37–$62
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 26.4 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $8 in charging
· 0 stops
· 65% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
22.6
0
$7.92
$3.62
Efficient EV
18.9
0
$6.60
$3.02
EV Truck/SUV
30.2
0
$10.56
$4.83
Gas CO2
26 kg
EV CO2
9 kg (65% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 18, 2026
Origin
Endicott, NY
Late night
in Endicott on Sunday
Local time
2:01 AM
EDT
Current temp
47°F
Unavailable
Live forecast
Destination
Syracuse, NY
Late night
in Syracuse on Sunday
Local time
2:01 AM
EDT
Current temp
57°F
Unavailable
Live forecast
39°F
Nanticoke, NY
38 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
10 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
1h 37m on the road
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
Harriet Tubman National Historical Park
National Historical Park
Harriet Tubman was guided by a deep faith and devotion to family, freedom, and community. After emancipating herself and members of her family, she moved them from Ontario, Canada to Fleming and Aubur...
22 mi from route
~54 min detour
Free
near mile 67.6
Park data from the National Park Service API. Alerts update every 2 hours.
More Details
What kind of drive is this?
This drive is primarily highway-focused, with 86% of your time spent on major roads. You will rely on I-81, State Highway 26, and the Union Center-Maine Highway to navigate the distance. The most significant portion of your travel involves a 52.7-mile stretch on I-81, which provides a consistent pace for the majority of the trip. While the route begins with local connections like the Union Center-Maine Highway, it quickly transitions into a more streamlined interstate experience. Expect a steady, predictable flow of traffic as you move from the Southern Tier toward the Syracuse area.
86% highway — fuel and pacing are the main things to plan.
21 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 52.7 mi on I 81.
How Hard Is This Drive?
5/10
This is a straightforward highway drive that stays mostly on I 81 and State Highway 26. You will hit about 10 points where you need to pay attention to lane position or signs. The trickiest moment comes early in the drive near Jefferson Avenue.
Driving Effort5/10
Moderate - straightforward overall, but long enough or busy enough to require pacing
Balances navigation complexity with total wheel time.
This drive requires moderate attention. Across 75.4 miles you will encounter 10 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.
Where does it get tricky?
The main spots that need attention: near the start (Jefferson Avenue): Navigation decision point; at 20 miles (US 11; NY 26): Navigation decision point; at 71.9 miles (I 81): Highway fork - watch signs carefully. Lane positioning matters here.
Binghamton is a city of 48,000 people (2020) in upstate New York, at the confluence of the Susquehanna and Chenango Rivers. It is the cultural and financial center of the Greater Binghamton Metropolitan Area and is the Broome County seat. Binghamton is part of the "Triple Cities" with Endicott and Johnson City.
Binghamton has many fantastic examples of Romanesque Revival Architecture in the city's center; for this, and for its collection of ornate mansions and nice homes, it's known as the Parlor City. The Binghamton area is also known as the Carousel Capital of America, home to 6 of the remaining 150 antique carousels in the nation. Other historic attractions are the Roberson Museum, Kopernik Space Center, and the Ross Park Zoo.
Rod Serling, the screenwriter and television producer, was born here, and the regional sandwich known as the "spiedie" was created here.
Syracuse is a city in Central New York. With a population of 149,000 in city proper and 662,000 in its metro area (2020), Syracuse is the fifth largest city in the state of New York, and the third largest in Upstate New York.
Top landmarks
•Oncenter War Memorial Arena — arena in Syracuse, New York
•Everson Museum of Art — art museum in Syracuse, New York
•Niagara Mohawk Building — historic commercial building in New York, United States
Doable as a same-day drive at 1h 37m. Total distance: 75.4 miles.
Family Friendly
Moderate complexity with 0 natural rest stops along the way.
Solo Traveler
1h 37m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (86%). Some complex stretches to watch for.
Frequently Asked Questions
The longest stretch is about 52.7 miles on I 81. The full list of main roads is in the Roads section above.
Yes. At under 2 hours behind the wheel, this works well for families — plan one quick stop if you have younger kids.
The main spots that need attention: near the start (Jefferson Avenue): Navigation decision point; at 20 miles (US 11; NY 26): Navigation decision point; at 71.9 miles (I 81): Highway fork - watch signs carefully. Lane positioning matters here.
Yes — Harriet Tubman National Historical Park. See the National Parks section for detour distances and tips on detours.
Yes. A round trip is manageable in a single day if you plan a break at Syracuse, NY before heading back.
