Traveling from East Dennis to Lowell covers 106.5 miles and typically takes about 2 hours and 26 minutes behind the wheel. Because this journey is relatively short, it is perfectly suited for a single-day trip, allowing you to reach your destination without the need for an overnight stay. You should budget approximately $17 for fuel to complete the trek. The route transitions from the coastal environment of the Cape to the historic industrial landscape of the Merrimack Valley. Whether you are heading north for business or a visit, the simple logistics make this a straightforward drive within Massachusetts.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Midpoint
53.3 miles from East Dennis, MA
A natural place for your longest stop of the day
, about 1h 12m into the drive
.
Main Roads
Road
Distance
Duration
Pilgrims Highway
42.3 mi
53m
Mid Cape Highway
22.3 mi
30m
US 3
10.9 mi
13m
MA 3
8.4 mi
11m
John F. Fitzgerald Expressway
3.2 mi
5m
I 93
3.1 mi
4m
East West Dennis Road
3 mi
5m
Cambridge Road
2 mi
2m
Longest stretch:
Pilgrims Highway
— 42.3 mi, about 53m
Turn-by-Turn Driving Directions
Step-by-step road directions between East Dennis, MA and City of Lowell, MA.
1
Start on this road
186 ft·13 sec·this road
2
Turn right onto MA 134
3.0 mi·5 min·East West Dennis Road
3
Take the ramp
0.4 mi·54 sec
Toward US 6 West: Hyannis, Boston
4
Merge onto US 6
22 mi·30 min·Mid Cape Highway
5
Continue on US 6
0.4 mi·45 sec·Sagamore Bridge
6
Continue on US 6
0.3 mi·20 sec·Pilgrim Highway
7
Continue on MA 3
42 mi·53 min·Pilgrims Highway
Use the straight / slight right lanes.
8
Continue on MA 3
8.4 mi·11 min·MA 3
Exit 43BToward I 93 North: BostonUse the straight / slight right lanes.
9
Continue on I 93; US 1; MA 3
3.2 mi·5 min·John F. Fitzgerald Expressway
Use the straight / slight right lanes.
10
Keep slight right at fork onto I 93
3.1 mi·4 min·I 93
Toward I 93 North: Concord NHUse the straight / slight left lanes.
11
Take the exit
0.2 mi·31 sec
Exit 22Toward MA 16 West: Mystic Valley Parkway, ArlingtonUse the slight right lane.
12
Continue on MA 16
1.1 mi·2 min·Mystic Valley Parkway
13
Turn right onto MA 38
0.1 mi·22 sec·Winthrop Street
Use the right lane.
14
Enter roundabout onto Winthrop Street
117 ft·2 sec·Winthrop Street
15
Continue on Winthrop Street
1.3 mi·1 min·Winthrop Street
16
Continue on MA 38
0.5 mi·46 sec·Main Street
17
Enter roundabout onto Bacon Street
94 ft·1 sec·Bacon Street
18
Continue on Bacon Street
0.7 mi·1 min·Bacon Street
19
Turn left onto Church Street
0.3 mi·38 sec·Church Street
20
Turn right onto US 3
1.1 mi·1 min·Cambridge Street
21
Continue on US 3
2.0 mi·2 min·Cambridge Road
22
Continue on US 3
0.6 mi·47 sec·Cambridge Street
23
Take the exit onto US 3
0.2 mi·27 sec·US 3
Toward I 95 South, US 3 North: Waltham, Lowell
24
Merge onto I 95; US 3; MA 128
1.1 mi·1 min·Yankee Division Highway
Use the straight / right lanes.
25
Take the exit onto US 3
0.1 mi·15 sec·US 3
Exit 50B-AToward US 3 North: Lowell, Middlesex Turnpike, Burlington, Nashua New HampshireUse the straight / slight right lanes.
26
Keep slight left at fork onto US 3
0.3 mi·34 sec·US 3
Toward US 3 North: Lowell, Nashua New Hampshire
27
Keep slight right at fork onto US 3
9.8 mi·11 min·US 3
Exit 50AToward US 3 North: Lowell, Nashua New Hampshire
28
Keep slight left at fork onto US 3
0.5 mi·32 sec·US 3
Use the straight / slight right lanes.
29
Take the exit
0.4 mi·43 sec
Exit 81B-CToward MA 110, I 495 South: Chelmsford, MarlboroUse the straight / slight right lanes.
30
Keep slight left at fork
0.3 mi·21 sec
Toward MA 110: Lowell, Chelmsford
31
Keep slight right at fork
0.2 mi·23 sec
Exit 81CToward MA 110: Lowell, Chelmsford
32
Turn right onto MA 110
1.8 mi·2 min·Chelmsford Street
33
Turn sharp left onto MA 3A
458 ft·10 sec·Westford Street
34
Turn right onto Grand Street
448 ft·23 sec·Grand Street
35
At end of road, turn left onto Middlesex Street
383 ft·18 sec·Middlesex Street
36
Turn sharp right onto Arch Street
15 ft·5 sec·Arch Street
37
Turn left
0.1 mi·38 sec
38
Arrive at destination
Trip Plan
Planning your departure is key to managing the 2-hour and 26-minute duration, as local traffic can fluctuate significantly throughout the day. Since there are no mandatory stops built into this 106.5-mile route, you have the flexibility to pull over whenever you need a break or a quick refueling session. Keep in mind that the final leg of the trip is less highway-dependent, so factor in extra time for navigating local turns. To ensure a smooth arrival, check your GPS for real-time congestion updates before hitting US-3. Staying alert during the final, more technical portion of the drive will help you arrive in Lowell feeling refreshed and ready for your destination.
Morning Departure
Leave by 9 AM and you'll arrive before lunch.
Evening Departure
Even a 4 PM departure gets you there before dark in summer.
You can normally do this drive in one day.
You may only need one short stretch break if traffic stays light.
The halfway point lands around 53.3 miles from East Dennis, MA, or about 1h 12m into the drive.
The longest continuous stretch on this route runs about 42.3 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 23 miles or 33m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 53.3 miles or 1h 12m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 2h
Traffic, exits, and arrival timing usually matter more near City of Lowell, MA than in the middle of the route.
Before You Leave
+
Open the route before leaving East Dennis, MA so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from East Dennis, MA
This is one driving day of about 106.5 miles and 2h 26m.
Your first comfortable stop window is around 23 miles from East Dennis, MA.
This route can stay practical as a one-day drive if traffic stays reasonable.
The longest stretch is on Pilgrims Highway for about 42.3 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 25
5 decision points cluster between mile 80.3 and 104.2 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
7
80.3 mi into trip|~1h 48m in|I 93
Keep slight right at fork onto I 93 toward I 93 North: Concord NH
Highway fork - watch signs carefully. Lane positioning matters here
Use the straight / slight left lanes.
Toward I 93 North: Concord NH
8
83.4 mi into trip|~1h 52m in
Take the exit toward MA 16 West: Mystic Valley Parkway, Arlington
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight right lane.
Exit 22
Toward MA 16 West: Mystic Valley Parkway, Arlin...
8
92.8 mi into trip|~2h 7m in|US 3
Take the exit onto US 3 toward US 3 North: Lowell, Middlesex Turnpike, Burlington, Nashua New Hampshire
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / slight right lanes.
Exit 50B-A
Toward US 3 North: Lowell, Middlesex Turnpike,...
8
103.5 mi into trip|~2h 20m in
Take the exit toward MA 110, I 495 South: Chelmsford, Marlboro
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / slight right lanes.
Exit 81B-C
Toward MA 110, I 495 South: Chelmsford, Marlbor...
8
104.2 mi into trip|~2h 22m in
Keep slight right at fork toward MA 110: Lowell, Chelmsford
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Exit 81C
Toward MA 110: Lowell, Chelmsford
Fuel & Cost
Regular Gas
$17.04 one way
$34.09 round trip
$4.07/gal25.4 MPG avg37 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.43
$18.59
$37.17
premium
$4.82
$20.22
$40.44
diesel
$5.61
$23.51
$47.03
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$17
Meals
$25–$50
Total
$42–$67
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 37.3 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $11 in charging
· 0 stops
· 68% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
32
0
$11.18
$5.11
Efficient EV
26.6
0
$9.32
$4.26
EV Truck/SUV
42.6
0
$14.91
$6.82
Gas CO2
37 kg
EV CO2
12 kg (68% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Feb 15, 2022
Origin
East Dennis, MA
Late night
in East Dennis on Sunday
Local time
12:48 AM
EDT
Current temp
37°F
Unavailable
Live forecast
Destination
City of Lowell, MA
Late night
in City of Lowell on Sunday
Local time
12:48 AM
EDT
Current temp
63°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
26 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
2h 26m on the road
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
Adams National Historical Park
National Historical Park
From the sweet little farm at the foot of Penn’s Hill to the gentleman’s country estate at Peace field, Adams National Historical Park is the story of “heroes, statesmen, philosophers…and learned wome...
Discover how one city could be the Cradle of Liberty, site of the first major battle of American Revolution, and home to many who espoused that freedom can be extended to all.
Lowell’s water-powered textile mills catapulted the nation – including immigrant families and early female factory workers – into an uncertain new industrial era. Nearly 200 years later, the changes t...
1 mi from route
~1 min detour
Free
near mile 106.5
At Minute Man National Historical Park the opening battle of the Revolution is brought to life as visitors explore the battlefields and structures associated with April 19, 1775, and witness the Ameri...
5 mi from route
~11 min detour
Free
near mile 95.5
. . . where you can walk a Civil War-era fort, view historic lighthouses, explore tide pools, hike lush trails, camp under the stars, or relax while fishing, picnicking, or swimming—all within reach o...
6 mi from route
~14 min detour
Free
near mile 73.5
The great Outer Beach described by Thoreau in the 1800s is protected within the national seashore. Forty miles of pristine sandy beach, marshes, ponds, and uplands support diverse species. Lighthouses...
Park data from the National Park Service API. Alerts update every 2 hours.
More Details
What kind of drive is this?
This trip features a distinct mix of driving styles, starting with a significant highway portion before transitioning into a turn-heavy local drive. You will spend roughly 25% of your time on highways, with your longest uninterrupted stretch covering 42.3 miles along the Pilgrims Highway. Expect to navigate the Mid-Cape Highway and US-3 as you work your way toward Lowell. The character of the road shifts noticeably as you leave the highway system, requiring more attention to navigation and local traffic patterns. Prepare for a varied experience that balances higher-speed transit with more technical, winding local segments.
Only 25% highway — the rest is turn-by-turn surface driving.
38 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 42.3 mi on Pilgrims Highway.
How Hard Is This Drive?
10/10
Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 80.3 miles in near I 93.
Driving Effort10/10
High effort - long or complex enough to need steady focus all day
Balances navigation complexity with total wheel time.
This is a demanding drive. With 25 significant decision points across 106.5 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 80.3 miles (I 93): Highway fork - watch signs carefully. Lane positioning matters here; at 83.4 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 92.8 miles (US 3): Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between East Dennis, MA and City of Lowell, MA, road signs point toward Arlington, Lowell, Middlesex Turnpike, Burlington and Nashua New Hampshire.
Arlington
83.4 mi in|~1h 52m
Lowell
91.5 mi in|~2h 5m|via US 3
Middlesex Turnpike
92.8 mi in|~2h 7m|via US 3
Burlington
92.8 mi in|~2h 7m|via US 3
Nashua New Hampshire
92.8 mi in|~2h 7m|via US 3
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 2h 26m. Total distance: 106.5 miles.
Family Friendly
Moderate complexity with 0 natural rest stops along the way.
Solo Traveler
2h 26m drive, comfortable solo distance.
Scenic Drive
Mostly surface roads route profile with national parks nearby.
Frequently Asked Questions
The longest stretch is about 42.3 miles on Pilgrims Highway. The full list of main roads is in the Roads section above.
It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at City of Lowell, MA before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Dedicated rest areas are limited, so plan gas or food stops as your bathroom breaks.
The main spots that need attention: at 80.3 miles (I 93): Highway fork - watch signs carefully. Lane positioning matters here; at 83.4 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 92.8 miles (US 3): Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Yes — Adams National Historical Park, Boston National Historical Park and Lowell National Historical Park (6 total within detour distance). See the National Parks section for detour distances and tips on detours.
Yes. A round trip is manageable in a single day if you plan a break at City of Lowell, MA before heading back.
