Cincinnati to Mayfield is 32.7 miles and takes about 46 minutes via Mill Creek Expressway, with a fuel budget near $5 and enough daylight to finish in a day. This short trip stays within Ohio, moving you through the Midwest region. Given its brief duration, this route is ideal for a quick transition or an add-on to a larger trip. You'll find it's a straightforward drive with minimal time commitment, making it easy to fit into a busy schedule.
Main Roads
Road
Distance
Duration
Mill Creek Expressway
25.6 mi
31m
SR 122
2.8 mi
4m
Vine Street
2 mi
4m
Jefferson Avenue
0.5 mi
1m
West Mitchell Avenue
0.3 mi
<1m
Sheffield Street
0.2 mi
<1m
Kensington Street
0.2 mi
<1m
West McMillan Avenue
0.2 mi
<1m
Longest stretch:
Mill Creek Expressway
— 25.6 mi, about 31m
Turn-by-Turn Driving Directions
Step-by-step road directions between Cincinnati, OH and Mayfield, OH.
1
Start on Ohio Avenue
99 ft·6 sec·Ohio Avenue
2
Turn right onto West McMillan Avenue
0.2 mi·27 sec·West McMillan Avenue
3
Turn left onto Vine Street
282 ft·10 sec·Vine Street
4
Continue on Jefferson Avenue
0.5 mi·1 min·Jefferson Avenue
Use the straight lane.
5
Continue on Vine Street
2.0 mi·4 min·Vine Street
Use the left lane.
6
Turn left onto West Mitchell Avenue
0.3 mi·39 sec·West Mitchell Avenue
Use the left lane.
7
Take the ramp
0.4 mi·49 sec
Toward I 75 North: Dayton
8
Merge onto I 75
26 mi·31 min·Mill Creek Expressway
Use the straight / slight right lanes.
9
Take the exit
0.5 mi·1 min
Exit 32Toward SR 122: MiddletownUse the slight right lane.
10
Turn left onto SR 122
2.8 mi·4 min·SR 122
Use the left / straight / right lanes.
11
Turn left onto Kensington Street
266 ft·13 sec·Kensington Street
Use the left lane.
12
Continue on Kensington Street
0.2 mi·45 sec·Kensington Street
13
Turn left onto Sheffield Street
0.2 mi·52 sec·Sheffield Street
14
Arrive at destination
Sheffield Street
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
The midpoint is around 16.3 miles from Cincinnati, OH, which is a good place for a longer meal and fuel stop.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Heads-up: tricky spots
5 of 9
5 decision points cluster between mile 0 and 29 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
4
0 mi into trip|~0m in|West McMillan Avenue
Turn right onto West McMillan Avenue
Navigation decision point
4
0.2 mi into trip|~0m in|Vine Street
Turn left onto Vine Street
Navigation decision point
5
2.8 mi into trip|~6m in|West Mitchell Avenue
Turn left onto West Mitchell Avenue
Lane positioning matters here
Use the left lane.
5
3.4 mi into trip|~8m in|I 75 / Mill Creek Expressway
Merge onto I 75 / Mill Creek Expressway
Merge point - match speed before joining. Lane positioning matters here
Use the straight / slight right lanes.
7
29 mi into trip|~39m in
Take the exit toward SR 122: Middletown
Exit ramp - move to the correct lane early. Lane positioning matters here
Use the slight right lane.
Exit 32
Toward SR 122: Middletown
Fuel & Cost
Regular Gas
$5.07 one way
$10.15 round trip
$3.94/gal25.4 MPG avg11 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.38
$5.63
$11.26
premium
$4.91
$6.32
$12.64
diesel
$5.61
$7.22
$14.44
No toll roads detected on this route.
Drive Cost (one way)
Fuel
$5
Estimated CO2 emission: 11.4 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $3 in charging
· 0 stops
· 64% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
9.8
0
$3.43
$1.57
Efficient EV
8.2
0
$2.86
$1.31
EV Truck/SUV
13.1
0
$4.58
$2.09
Gas CO2
11 kg
EV CO2
4 kg (64% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 18, 2026
Origin
Cincinnati, OH
Afternoon
in Cincinnati on Sunday
Local time
12:14 PM
EDT
Current temp
75°F
Showers And Thunderstorms Likely
W 14 mph68% chanceLive forecast
Special Weather Statement
Special Weather Statement issued April 18 at 3:09PM EDT by NWS Charleston WV
Freeze Watch
Freeze Watch issued April 18 at 2:54PM EDT until April 20 at 9:00AM EDT by NWS Wilmington OH
Destination
Mayfield, OH
Afternoon
in Mayfield on Sunday
Local time
12:14 PM
EDT
Current temp
74°F
Showers And Thunderstorms Likely
NW 14 mph64% chanceLive forecast
Special Weather Statement
Special Weather Statement issued April 18 at 3:09PM EDT by NWS Charleston WV
Freeze Watch
Freeze Watch issued April 18 at 2:54PM EDT until April 20 at 9:00AM EDT by NWS Wilmington OH
77°F
Lincoln Heights, OH
16 mi in
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
1 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
46m on the road
The weather snapshot is not static. If you are leaving later, give both cities one more quick forecast check before departure.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
More Details
What kind of drive is this?
This drive is predominantly highway, with 87% of the 32.7 miles on high-speed roads. You'll spend the longest stretch, 25.6 miles, on the Mill Creek Expressway. Expect a concentrated number of exits and merges on this busy expressway. The final leg will transition to surface roads like SR 122 and Vine Street as you approach your destination.
87% highway — fuel and pacing are the main things to plan.
14 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 25.6 mi on Mill Creek Expressway.
How Hard Is This Drive?
6/10
This is a straightforward highway drive that stays mostly on Mill Creek Expressway and SR 122. You will hit about 9 points where you need to pay attention to lane position or signs. The trickiest moment comes early in the drive near West McMillan Avenue.
Driving Effort6/10
Moderate - straightforward overall, but long enough or busy enough to require pacing
Balances navigation complexity with total wheel time.
This drive requires moderate attention. Across 32.7 miles you will encounter 9 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.
Where does it get tricky?
The main spots that need attention: near the start (West McMillan Avenue): Navigation decision point; at 0.2 miles (Vine Street): Navigation decision point; at 2.8 miles (West Mitchell Avenue): Lane positioning matters here.
Cincinnati is Ohio's third largest city and the largest metro region, and lies on the north bank of the Ohio River in Southwest Ohio in the United States of America.
Cincinnati is distinct amongst Midwestern cities. Its culture is a mixture of the Northeast, Old South, Midwest, and Appalachia blended with a strong German-Catholic heritage. It was one of the United States' early boomtowns, and the Over-the-Rhine neighborhood is the largest National Historic District in the country. Today, it's part of a fast-growing metro area, and home to a remarkable blend of industry and architecture. Downtown Cincinnati is surrounded by picturesque foothills that add a beautiful backdrop to the Queen City and its legendary skyline – celebrated in the opening credits of television show WKRP in Cincinnati.
Top landmarks
•Carew Tower — skyscraper in Cincinnati, Ohio, United States
•Cathedral Basilica of St. Peter in Chains — cathedral of the Roman Catholic Archdiocese of Cincinnati in downtown Cincinnati...
•Cincinnati Observatory — other organization in Cincinnati, United States
Doable as a same-day drive at 46m. Total distance: 32.7 miles.
Family Friendly
Moderate complexity with 0 natural rest stops along the way.
Solo Traveler
46m drive, comfortable solo distance.
EV Driver
0 DC fast chargers along the route. Coverage: unknown.
First-Time Driver
Mostly highway driving (87%). Some complex stretches to watch for.
Frequently Asked Questions
The longest stretch is about 25.6 miles on Mill Creek Expressway. The full list of main roads is in the Roads section above.
Yes — we found about 2 rest areas or service plazas within a short detour of the route (from OpenStreetMap). See the Rest Stops tab under Nearby Places for locations and mile markers. Plan to stretch, use the bathroom, and top off fluids every 2–3 hours on longer drives.
It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Mayfield, OH before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Yes. At under 2 hours behind the wheel, this works well for families — plan one quick stop if you have younger kids.
The main spots that need attention: near the start (West McMillan Avenue): Navigation decision point; at 0.2 miles (Vine Street): Navigation decision point; at 2.8 miles (West Mitchell Avenue): Lane positioning matters here.
Yes — Dayton Aviation Heritage National Historical Park and Charles Young Buffalo Soldiers National Monument. See the National Parks section for detour distances and tips on detours.
Yes. A round trip is manageable in a single day if you plan a break at Mayfield, OH before heading back.
