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Trip from Carlisle, IA to Ames, IA

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Compiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Apr 21, 2026 · Editorial standards

Drive Time

55m

Distance

45 mi

72 km

Drive Score

8/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$7

one way

EV Charging

Unknown

Best Time to Leave

Save up to 14 min
4 AM
0h 51m ★
6 AM
0h 56m
8 AM
1h 5m
10 AM
0h 59m
12 PM
0h 58m
3 PM
0h 59m
5 PM
1h 4m
8 PM
0h 53m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

Downtown Carlisle, IA, IA

Carlisle, IA

Quang Nguyen Vinh

city in Story County, Iowa, United States

Ames, IA

Wikimedia Commons

Trip Overview

This straightforward 45-mile drive from Carlisle, IA to Ames, IA takes about 55 minutes, making it an easy day trip. You'll spend about 63% of your time on highways, primarily utilizing I-35, also known as the Military Order of the Purple Heart Highway. With a fuel cost estimated at $7, this short journey is budget-friendly. The route stays within the Midwest region, offering a consistent feel throughout. Given its brevity, you won't need an overnight stop, and you can easily fit this into a busy schedule.

Main Roads

Road Distance Duration
I 35 25.7 mi 28m
Military Order of the Purple Heart Highway 10.3 mi 11m
East 13th Street 2.7 mi 5m
IA 5 1.7 mi 1m
I 80 0.9 mi 1m
North 5th Street 0.3 mi 1m
13th Street

Some road-level metrics are being recalculated.

Longest stretch: I 35 — 25.7 mi, about 28m

Turn-by-Turn Driving Directions

Step-by-step road directions between Carlisle, IA and Ames, IA.

1

Start on North 5th Street

0.3 mi · 1 min · North 5th Street
2

Turn right onto IA 5

1.7 mi · 1 min · IA 5
3

Take the exit

0.5 mi · 1 min
4

Merge onto US 65

10 mi · 11 min · Military Order of the Purple Heart Highway
5

Take the exit

1.2 mi · 1 min
Exit 84 Toward I 80 West: Council Bluffs
6

Merge onto I 80

0.9 mi · 1 min · I 80
7

Take the exit

0.5 mi · 1 min
Exit 137B Toward I-35 north: Minneapolis Use the straight / slight right lanes.
8

Continue on this road

0.3 mi · 42 sec · this road
Exit 137B Toward I-35 north: Minneapolis
9

Continue on this road

0.5 mi · 52 sec · this road
Exit 137B Toward I-35 North: Minneapolis
10

Merge onto I 35

26 mi · 28 min · I 35
Toward I 35 North: Minneapolis Use the straight / slight right lanes.
11

Take the exit

0.3 mi · 44 sec
Toward USDA Veterinary Labs
12

Turn left onto East 13th Street

2.7 mi · 5 min · East 13th Street
13

Arrive at destination

I 35 Business

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

city in Polk County, Iowa, United States

Mid-route town

Meal stop

Ankeny, IA

23 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

Altoona, IA

Fuel and coffee

A short stop after about 10 miles helps settle the day before fatigue starts building.

Ankeny, IA

Meal break

The midpoint is around 22.5 miles from Carlisle, IA, which is a good place for a longer meal and fuel stop.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Heads-up: tricky spots

5 of 8

5 decision points cluster between mile 0.3 and 42 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.

4
0.3 mi into trip | ~1m in | IA 5

Turn right onto IA 5

Navigation decision point

5
12.8 mi into trip | ~16m in

Take the exit toward I 80 West: Council Bluffs

Exit ramp - move to the correct lane early

Exit 84 Toward I 80 West: Council Bluffs
7
14.9 mi into trip | ~18m in

Take the exit toward I-35 north: Minneapolis

Exit ramp - move to the correct lane early. Lane positioning matters here

Use the straight / slight right lanes. Exit 137B Toward I-35 north: Minneapolis
6
16.3 mi into trip | ~21m in | I 35

Merge onto I 35 toward I 35 North: Minneapolis

Merge point - match speed before joining. Lane positioning matters here

Use the straight / slight right lanes. Toward I 35 North: Minneapolis
4
42 mi into trip | ~49m in

Take the exit toward USDA Veterinary Labs

Exit ramp - move to the correct lane early

Toward USDA Veterinary Labs

Fuel & Cost

Regular Gas

$7.04 one way

$14.07 round trip

$3.97/gal 25.4 MPG avg 16 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.36 $7.72 $15.45
premium $4.89 $8.66 $17.32
diesel $5.61 $9.94 $19.87

No toll roads detected on this route.

Drive Cost (one way)

Fuel

$7

Estimated CO2 emission: 15.7 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $5 in charging · 0 stops · 69% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 13.5 0 $4.73 $2.16
Efficient EV 11.3 0 $3.94 $1.80
EV Truck/SUV 18 0 $6.30 $2.88

Gas CO2

16 kg

EV CO2

5 kg (69% less)

This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Apr 20, 2026

Origin

Carlisle, IA

Late night in Carlisle on Tuesday

Local time

5:25 AM

CDT

Current temp

61°F

Unavailable

Live forecast

Destination

Ames, IA

Late night in Ames on Tuesday

Local time

5:25 AM

CDT

Current temp

60°F

Unavailable

Live forecast

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

1 degrees cooler at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

55m on the road

Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

What kind of drive is this?

Expect a highway-focused experience for most of this drive, with 63% of your travel on interstate roads. The longest uninterrupted stretch you'll encounter is 25.7 miles on I-35, providing a good opportunity to settle in. While primarily interstate, the route does transition to surface streets like East 13th Street as you approach your destination. This means you'll experience a mix of faster highway speeds and more typical in-town driving conditions toward the end.

63% highway — fuel and pacing are the main things to plan.
13 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 25.7 mi on I 35.

How Hard Is This Drive?

5/10

This is a straightforward highway drive that stays mostly on I 35 and Military Order of the Purple Heart Highway. You will hit about 8 points where you need to pay attention to lane position or signs. The trickiest moment comes around 0.3 miles in near IA 5.

Driving Effort 5/10

Moderate - straightforward overall, but long enough or busy enough to require pacing

Balances navigation complexity with total wheel time.

This drive requires moderate attention. Across 45 miles you will encounter 8 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.

Where does it get tricky?

The main spots that need attention: at 0.3 miles (IA 5): Navigation decision point; at 12.8 miles: Exit ramp - move to the correct lane early; at 14.9 miles: Exit ramp - move to the correct lane early. Lane positioning matters here.

Towns Mentioned on Route Signs

Based on OSRM destination-sign hints, not a full list of every settlement the road passes.

On the drive from Carlisle, IA to Ames, IA, road signs begin pointing toward Usda Veterinary Labs along the way.

Usda Veterinary Labs

42 mi in | ~49m

About the Cities

Arriving in Ames, IA

Full guide →

Founded 1864

Ames is a pleasant college town in Central Iowa, sitting astride the Skunk River roughly 30 miles north of Des Moines. Life in Ames follows the ebb and flow of the academic year at Iowa State University, which is the city's primary draw.

Top landmarks

  • Catt Hall — building on Iowa State University's campus, U.S.
  • Food Sciences Building — historic building on the campus of Iowa State University in Ames, Iowa, United S...
  • Ames City Hall — United States historic place

City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).

Who Is This Route For?

Weekend Trip

Doable as a same-day drive at 55m. Total distance: 45 miles.

Family Friendly

Moderate complexity with 0 natural rest stops along the way.

Solo Traveler

55m drive, comfortable solo distance.

EV Driver

0 DC fast chargers along the route. Coverage: unknown.

First-Time Driver

Mostly highway driving (63%). Some complex stretches to watch for.

Frequently Asked Questions

The longest stretch is about 25.7 miles on I 35. The full list of main roads is in the Roads section above.

Yes. At under 2 hours behind the wheel, this works well for families — plan one quick stop if you have younger kids.

The main spots that need attention: at 0.3 miles (IA 5): Navigation decision point; at 12.8 miles: Exit ramp - move to the correct lane early; at 14.9 miles: Exit ramp - move to the correct lane early. Lane positioning matters here.

Yes. A round trip is manageable in a single day if you plan a break at Ames, IA before heading back.

How this page is built

Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, and EIA for fuel prices. See our methodology for refresh cadence and limitations.

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