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Trip from Cape Coral, FL to Myrtle Grove, FL

Compiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Apr 19, 2026 · Editorial standards

Drive Time

11h

Distance

595.5 mi

958 km

Drive Score

8/10

Great drive

Same Day?

2-day trip

Fuel Cost

$95

one way

EV Charging

Excellent

26 DC fast

Best Time to Leave

Save up to 30 min
4 AM
10h 50m ★
6 AM
11h 0m
8 AM
11h 20m
10 AM
11h 7m
12 PM
11h 5m
3 PM
11h 8m
5 PM
11h 19m
8 PM
10h 54m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

city in Lee County, Florida, United States

Cape Coral, FL

Wikimedia Commons

Downtown Myrtle Grove, FL, FL

Myrtle Grove, FL

Amber Costello

Trip Overview

The drive from Cape Coral, FL to Myrtle Grove, FL covers 595.5 miles and takes about 11h behind the wheel. It usually feels better as a 2-day road trip than as one long push.

The route leans on I 10, I 75, North Tamiami Trail for much of the mileage, and the overall profile is long-haul drive. The longest uninterrupted segment is about 283.4 miles on I 10. At current regular gas prices, budget about $94.79 one way before food or hotel costs.

Trip Pace

Best split across 2 days

Treat the return leg as its own travel day rather than an afterthought.

Break Rhythm

3 planned breaks

Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

Midpoint

297.8 miles from Cape Coral, FL

A natural place for your longest stop of the day , about 5h 33m into the drive .

Main Roads

Road Distance Duration
I 10 283.4 mi 5h 3m
I 75 276.8 mi 4h 57m
North Tamiami Trail 10.4 mi 12m
Del Prado Boulevard North 6.5 mi 10m
Del Prado Boulevard South 5.2 mi 10m
East Fairfield Drive 2.9 mi 5m
Reubin O'Donovan Askew Parkway 2.7 mi 3m
Fairfield Drive 1.6 mi 3m
Longest stretch: I 10 — 283.4 mi, about 5h 3m

Turn-by-Turn Driving Directions

Step-by-step road directions between Cape Coral, FL and Myrtle Grove, FL.

1

Start on this road

95 ft · 7 sec · this road
2

Turn right onto Cape Coral Parkway East

125 ft · 7 sec · Cape Coral Parkway East
3

Turn right onto Vincennes Boulevard

357 ft · 13 sec · Vincennes Boulevard
Use the right lane.
4

Enter roundabout onto Vincennes Boulevard

61 ft · 2 sec · Vincennes Boulevard
5

Continue on Vincennes Boulevard

0.5 mi · 1 min · Vincennes Boulevard
6

Turn right onto Coronado Parkway

0.6 mi · 1 min · Coronado Parkway
7

Turn left onto CR 867A

5.2 mi · 10 min · Del Prado Boulevard South
8

Continue on CR 867A

6.5 mi · 10 min · Del Prado Boulevard North
Use the left lane.
9

Turn left onto US 41

10 mi · 12 min · North Tamiami Trail
Use the right lane.
10

Turn right onto CR 762

1.1 mi · 2 min · Tuckers Grade
11

Take the ramp

0.4 mi · 56 sec
Toward I 75 North: Tampa
12

Merge onto I 75

277 mi · 4 hr 57 min · I 75
Use the straight / slight right lanes.
13

Take the exit

0.2 mi · 15 sec
Exit 435 Toward I 10: Jacksonville, Tallahassee Use the straight / slight right lanes.
14

Keep slight left at fork

0.3 mi · 30 sec
Toward I 10 West: Tallahassee Use the slight left / slight right lanes.
15

Merge onto I 10

283 mi · 5 hr 3 min · I 10
Use the straight / slight right lanes.
16

Take the exit

0.9 mi · 1 min
Exit 12 Toward I 110 South: Pensacola, Pensacola Beach Use the straight / slight right lanes.
17

Merge onto I 110

2.7 mi · 3 min · Reubin O'Donovan Askew Parkway
Use the straight / slight right lanes.
18

Take the exit

0.3 mi · 39 sec
Exit 4 Toward FL 295: Fairfield Drive Use the straight / slight right lanes.
19

Keep slight right at fork

0.1 mi · 17 sec
Toward FL 295 South
20

Turn straight onto FL 295

2.9 mi · 5 min · East Fairfield Drive
21

Continue on FL 727

1.6 mi · 3 min · Fairfield Drive
22

Turn left onto North 57th Avenue

0.4 mi · 1 min · North 57th Avenue
Use the left lane.
23

Turn right onto FL 298

1.0 mi · 2 min · Lillian Highway
24

Turn right

44 ft · 5 sec
25

Turn right

82 ft · 5 sec
26

Arrive at destination

Trip Plan

Morning Departure

Start early — leave by 6-7 AM to arrive at a reasonable hour.

Evening Departure

This is a long drive — plan for a morning departure or consider splitting it into two days.

This drive is better paced as a 2-day trip.
Plan roughly 3 meaningful breaks for fuel, food, and rest.
The halfway point lands around 297.8 miles from Cape Coral, FL, or about 5h 33m into the drive.
The longest continuous stretch on this route runs about 283.4 miles.

Consider an overnight stop or starting very early.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 131 miles or 2h 34m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 297.8 miles or 5h 33m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Overnight split

Day 1 wrap after about 297.8 miles or 5h 33m

Stop before fatigue turns the last few hours into a grind. You want day two to start fresh, not just resumed.

Final approach

Final hour starts around 9h 49m

Traffic, exits, and arrival timing usually matter more near Myrtle Grove, FL than in the middle of the route.

Before You Leave

+

Open the route before leaving Cape Coral, FL so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

+

Pick one backup stop option before the midpoint in case traffic changes your pacing.

+

Treat this as a 2-day road trip and book the overnight stop before the busiest arrival window.

Day 1

Settle into the route from Cape Coral, FL

Aim for roughly 298 miles and 5.5 hours of wheel time on this day.

Day 2

Finish the approach into Myrtle Grove, FL

Aim for roughly 298 miles and 5.5 hours of wheel time on this day.

Your first comfortable stop window is around 131 miles from Cape Coral, FL.
This route usually feels better as a 2-day drive than as one long push.
Plan about 3 real breaks rather than only quick fuel stops.
The longest stretch is on I 10 for about 283.4 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

census-designated place in Hillsborough County, Florida, United States

First major stop

Coffee and fuel

Mango, FL

197 mi into the route

Best for: Coffee, fuel, and an easy first stretch

This is a natural early stop once the first hours of the drive are behind you.

Downtown Tallahassee, FL, FL

Second major stop

Overnight candidate

Tallahassee, FL

393 mi into the route

Best for: Hotel check-in, dinner, and a fresh start

This lines up well with a realistic day-end stop if you are breaking the drive into stages.

Find hotels in Tallahassee, FL

Overnight Options

Night 1

Gainesville, FL

298 mi · about 5.5h in

A practical overnight split lands near Gainesville, FL after about 298 miles or 5.5 hours of driving.

Find hotels

Pacing Suggestions

Mango, FL

Fuel and coffee

A short stop after about 131 miles helps settle the day before fatigue starts building.

Lake City, FL

Meal break

The midpoint is around 297.8 miles from Cape Coral, FL, which is a good place for a longer meal and fuel stop.

Before the longest stretch

Fuel check

Top up before I 10 if your tank is already low. That segment runs about 283.4 miles.

Overnight split

Hotel stop

For a steadier pace, wrap day one after about 298 miles or 5.5 hours on the road.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Nearby Places

Restaurants, cafes, gas stations and more along your route.

Top Restaurant

Ellianos Coffee

4.8 ★ ★ ★ ★ ★

Lake City, Florida

Around the midpoint, short detour

2.1 mi from route ~5 min detour $1 to $10 mile 297.8

Hours: 6 am–8 pm

+13864388064

Visit website

Ellianos Coffee

4.7 ★ ★ ★ ★ ★

Lake City, Florida

2.7 mi

Two Cuban Guy's Home of Garcia's Place

4.7 ★ ★ ★ ★ ★

Lake City, Florida

2.9 mi

Top Coffee Stop

The Honeybee Café

4.9 ★ ★ ★ ★ ★

Gainesville, Florida

Around the midpoint, right off the route

0.9 mi from route ~2 min detour $10 to $20 mile 255.2

Hours: 8 am–3 pm

Visit website

CYM Coffee Co

4.5 ★ ★ ★ ★ ★

Gainesville, Florida

1.2 mi

Canal Coffee Company

4.9 ★ ★ ★ ★ ★

Lake City, Florida

2 mi

Ellianos Coffee

4.8 ★ ★ ★ ★ ★

Around the midpoint, short detour

2.1 mi from route ~5 min detour $1 to $10 mile 297.8

Lake City, Florida

Hours: 6 am–8 pm

+13864388064

Visit website

Ellianos Coffee

4.7 ★ ★ ★ ★ ★

Around the midpoint, short detour

2.7 mi from route ~7 min detour $1 to $10 mile 297.8

Lake City, Florida

Hours: 6 am–10 pm

+13867520202

Visit website

Two Cuban Guy's Home of Garcia's Place

4.7 ★ ★ ★ ★ ★

Around the midpoint, short detour

2.9 mi from route ~7 min detour $10 to $20 mile 297.8

Lake City, Florida

Hours: 11 am–6 pm

+13057755055

The Honeybee Café

4.9 ★ ★ ★ ★ ★

Around the midpoint, right off the route

0.9 mi from route ~2 min detour $10 to $20 mile 255.2

Gainesville, Florida

Hours: 8 am–3 pm

Visit website

CYM Coffee Co

4.5 ★ ★ ★ ★ ★

Around the midpoint, short detour

1.2 mi from route ~3 min detour $1 to $10 mile 255.2

Gainesville, Florida

Hours: 7 am–5 pm

+13522245101

Visit website

Canal Coffee Company

4.9 ★ ★ ★ ★ ★

Around the midpoint, short detour

2 mi from route ~5 min detour $1 to $10 mile 297.8

Lake City, Florida

Hours: 5 am–1 pm

+13864388426

Visit website

Resident Coffee

4.8 ★ ★ ★ ★ ★

Around the midpoint, short detour

2 mi from route ~5 min detour $10 to $20 mile 255.2

Gainesville, Florida

Hours: 8 am–3 pm

Visit website

108 Vine

4.8 ★ ★ ★ ★ ★

Around the midpoint, short detour

2.5 mi from route ~6 min detour $1 to $10 mile 255.2

Gainesville, Florida

Hours: 8 am–6 pm

Visit website

The Mission Coffee

4.7 ★ ★ ★ ★ ★

Around the midpoint, short detour

2.2 mi from route ~6 min detour $1 to $10 mile 255.2

Gainesville, Florida

Hours: 6:30 am–5 pm

+13523318554

Visit website

Opus Coffee - UF Health Springhill

4.5 ★ ★ ★ ★ ★

Around the midpoint, short detour

2.2 mi from route ~5 min detour $1 to $10 mile 255.2

Gainesville, Florida

Hours: 7:30 am–4 pm

+13522268512

Visit website

BW Blacksmith Coffee | Hwy 90

4.6 ★ ★ ★ ★ ★

Around the midpoint, ~9 min detour

3.6 mi from route ~9 min detour $1 to $10 mile 297.8

Lake City, Florida

Hours: 6:30 am–6 pm

+13864388553

Visit website

Tesla Supercharger

4.7 ★ ★ ★ ★ ★

Around the midpoint, right off the route

0.4 mi from route ~1 min detour mile 255.2

Gainesville, Florida

Hours: Open 24 hours

+18777983752

Visit website

Tesla Supercharger

4.6 ★ ★ ★ ★ ★

Early in the drive, short detour

1.5 mi from route ~4 min detour mile 170.1

Brooksville, Florida

Hours: Open 24 hours

Visit website

Tesla Destination Charger

3.0 ★ ★ ★ ☆ ☆

Around the midpoint, right off the route

0.2 mi from route mile 255.2

Gainesville, Florida

Hours: Open 24 hours

+13523326466

Visit website

Tesla Supercharger

4.7 ★ ★ ★ ★ ★

Around the midpoint, short detour

2.3 mi from route ~6 min detour mile 255.2

Gainesville, Florida

Hours: Open 24 hours

Visit website

Tesla Supercharger

4.1 ★ ★ ★ ★ ☆

Around the midpoint, short detour

2.7 mi from route ~7 min detour mile 297.8

Lake City, Florida

Hours: Open 24 hours

+18777983752

Visit website

Electric Vehicle Charging Station

3.9 ★ ★ ★ ★ ☆

Around the midpoint, short detour

2.5 mi from route ~6 min detour mile 297.8

Lake City, Florida

Hours: Open 24 hours

ChargePoint Charging Station

3.8 ★ ★ ★ ★ ☆

Near the end, short detour

2 mi from route ~5 min detour mile 595.5

Pensacola, Florida

Hours: Open 24 hours

+18887584389

Visit website

Blink Charging Station

1.7 ★ ★ ☆ ☆ ☆

Around the midpoint, right off the route

0.6 mi from route ~2 min detour mile 340.3

Madison, Florida

Hours: Open 24 hours

+18889982546

Visit website

Alachua County Rest Area (I-75 northbound)

0 mi from route

10270

0.1 mi from route

Pilot Travel Center

0.1 mi from route

Pilot Travel Center

0.1 mi from route

Pilot Travel Center

0.1 mi from route

Leon County Rest Area Westbound

0.1 mi from route

Leon County Rest Area Eastbound

0.1 mi from route

Jefferson County Rest Area Eastbound

0.1 mi from route

Okaloosa County Rest Area Westbound

0.1 mi from route

Jackson County Rest Area Westbound

0.1 mi from route

Jackson County Rest Area Eastbound

0.1 mi from route

Madison County Rest Area Eastbound

0.1 mi from route

Madison County Rest Area Westbound

0.1 mi from route

Columbia County Rest Area Westbound

0.1 mi from route

Pasco County Rest Area Northbound

0.1 mi from route

Pasco County Rest Area Southbound

0.1 mi from route

Columbia County Rest Area (I-75 southbound)

0.1 mi from route

Alachua County Rest Area (I-75 southbound)

0.1 mi from route

Marion County Rest Area Southbound

0.1 mi from route

Hillsborough County Rest Area Northbound

0.1 mi from route

Charlotte County Truck Stop Northbound

0.1 mi from route

Flying J Travel Center

0.1 mi from route

Love's Travel Stop

0.1 mi from route

Service Plaza

0.1 mi from route

Petro Stopping Centers

0.2 mi from route

Flying J Travel Center

0.2 mi from route

Pilot Travel Center

0.2 mi from route

TA

0.2 mi from route

Pilot Travel Center

0.2 mi from route

Columbia County Rest Area (I-75 northbound)

0.2 mi from route

Jefferson County Rest Area Westbound

0.2 mi from route

Santa Rosa County Rest Area Eastbound

0.2 mi from route

Okaloosa County Rest Area Eastbound

0.2 mi from route

Sumter County Rest Area Northbound

0.2 mi from route

Columbia County Rest Area (I-75 northbound)

0.2 mi from route

Marion County Rest Area Northbound

0.2 mi from route

Wildwood I-75 Weigh Station Southbound

0.2 mi from route

Hillsborough County Rest Area Southbound

0.2 mi from route

Ponce de Leon Rest Area

0.2 mi from route

Love's Travel Stop

0.2 mi from route

Pilot Travel Center

0.2 mi from route

Love's Travel Stop

0.2 mi from route

Service Plaza

0.2 mi from route

Love's Travel Stop

0.2 mi from route

Busy Bee Truck Stop

0.2 mi from route

TA

0.2 mi from route

Service Plaza

0.2 mi from route

Love's Travel Stop

0.2 mi from route

Love's Travel Stop

0.2 mi from route

TA

0.2 mi from route

ONE9 Travel Center

0.3 mi from route

Santa Rosa County Rest Area Westbound

0.3 mi from route

Suwannee County Rest Area Eastbound

0.3 mi from route

Wildwood I-75 Weigh Station Northbound

0.3 mi from route

Love's Travel Stop

0.3 mi from route

Pilot Travel Center

0.3 mi from route

Pilot Travel Center

0.4 mi from route

Gadsden County Rest Area

0.4 mi from route

Holmes County Rest Area

0.4 mi from route

Flying J Travel Center

1.5 mi from route

Service Plaza

1.5 mi from route

TA

1.6 mi from route

Santa Fe College Teaching Zoo

4.7 ★ ★ ★ ★ ★

Around the midpoint, short detour

1.8 mi from route ~5 min detour mile 255.2

Gainesville, Florida

Hours: 9 am–3 pm

+13523955633

Visit website

Cracker Country

4.7 ★ ★ ★ ★ ★

Early in the drive, short detour

2.2 mi from route ~5 min detour mile 127.6

Tampa, Florida

+18136274225

Visit website

Kika Silva Pla Planetarium at Santa Fe College

4.6 ★ ★ ★ ★ ★

Around the midpoint, short detour

1.6 mi from route ~4 min detour mile 255.2

Gainesville, Florida

Hours: Closed

+13523955381

Visit website

Kanapaha Botanical Gardens

4.7 ★ ★ ★ ★ ★

Around the midpoint, ~9 min detour

3.4 mi from route ~9 min detour mile 255.2

Gainesville, Florida

Hours: Closed

+13523724981

Visit website

Devil's Millhopper Geological State Park

4.5 ★ ★ ★ ★ ★

Around the midpoint, short detour

3.4 mi from route ~8 min detour mile 255.2

Gainesville, Florida

+13529552008

Visit website

Possum Creek Park

4.6 ★ ★ ★ ★ ★

Around the midpoint, ~9 min detour

3.5 mi from route ~9 min detour mile 255.2

Gainesville, Florida

+13523345067

Visit website

Tom Bennett Park

4.7 ★ ★ ★ ★ ★

Near the start, ~9 min detour

3.8 mi from route ~9 min detour mile 85.1

Bradenton, Florida

Hours: 7 am–8 pm

Visit website

Basketball (John H. Marble Rec Center)

4.4 ★ ★ ★ ★ ☆

Near the start, ~9 min detour

3.6 mi from route ~9 min detour mile 85.1

Bradenton, Florida

Hours: 6 am–9 pm

+19417456030

Visit website

Place data sourced from public business listings. Hours and availability may vary.

Heads-up: tricky spots

5 of 18

5 decision points cluster between mile 0 and 589.1 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.

7
0 mi into trip | ~0m in | Vincennes Boulevard

Turn right onto Vincennes Boulevard

Lane positioning matters here

Use the right lane.
8
301.7 mi into trip | ~5h 38m in

Take the exit toward I 10: Jacksonville, Tallahassee

Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one

Use the straight / slight right lanes. Exit 435 Toward I 10: Jacksonville, Tallahassee
8
301.8 mi into trip | ~5h 38m in

Keep slight left at fork toward I 10 West: Tallahassee

Highway fork - watch signs carefully. Lane positioning matters here

Use the slight left / slight right lanes. Toward I 10 West: Tallahassee
8
585.5 mi into trip | ~10h 42m in

Take the exit toward I 110 South: Pensacola, Pensacola Beach

Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one

Use the straight / slight right lanes. Exit 12 Toward I 110 South: Pensacola, Pensacola Beach
7
589.1 mi into trip | ~10h 46m in

Take the exit toward FL 295: Fairfield Drive

Exit ramp - move to the correct lane early. Lane positioning matters here

Use the straight / slight right lanes. Exit 4 Toward FL 295: Fairfield Drive

Fuel & Cost

Regular Gas

$94.79 one way

$189.58 round trip

$4.04/gal 25.4 MPG avg 208 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.40 $103.11 $206.22
premium $4.72 $110.73 $221.46
diesel $5.61 $131.48 $262.96

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$95

Hotel (1n)

$80–$140

Meals

$50–$100

Total

$225–$335

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 208.4 kg one way. Prices: EIA weekly data, 2026-04-13.

EV Charging Along Route

26 DC fast chargers · Coverage: excellent

Four Points by Sheraton - Tesla Supercharger

Punta Gorda, FL

Tesla

12 DCFC

Winn-Dixie - Tesla Supercharger

Punta Gorda, FL

Tesla

12 DCFC

Steak 'n Shake - Tesla Supercharger

Sarasota, FL

Tesla

12 DCFC

Wawa - Tesla Supercharger

Punta Gorda, FL

Tesla

8 DCFC

BrewBurgers - Tesla Supercharger

Venice, FL

Tesla

8 DCFC

Wawa - Tesla Supercharger

Sarasota, FL

Tesla

8 DCFC

Walmart 3349 (Port Charlotte, FL)

Port Charlotte, FL

Electrify America

6 DCFC

Electric Era Charging Station

North Port, FL

ELECTRIC_ERA

6 DCFC

Tesla: 6 ChargePoint Network: 5 FPLEV: 4 7CHARGE: 2 Blink Network: 2 CHARGESMART_EV: 1 Non-Networked: 1 Electrify America: 1 LOOP: 1 ELECTRIC_ERA: 1 JULE: 1 IN_CHARGE: 1

Station data from NREL Alternative Fuel Stations database.

Driving Electric?

About $63 in charging · 2 stops · 66% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 178.7 2 $62.53 $28.58
Efficient EV 148.9 1 $52.11 $23.82
EV Truck/SUV 238.2 2 $83.37 $38.11

Gas CO2

208 kg

EV CO2

70 kg (66% less)

Plan for 2 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Apr 15, 2026

Origin

Cape Coral, FL

Morning in Cape Coral on Sunday

Local time

7:32 AM

EDT

Current temp

66°F

Unavailable

Live forecast

Destination

Myrtle Grove, FL

Morning in Myrtle Grove on Sunday

Local time

6:32 AM

CDT

Current temp

60°F

Unavailable

Live forecast

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

For long drives, weather on day two can matter just as much as conditions at departure, so check the whole travel window rather than only the first day.

Time zone

1 hour earlier

The destination clock does not match departure time, so double-check hotel check-in windows and late arrival plans.

Temperature spread

6 degrees cooler at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

11h on the road

This is long enough that the arrival forecast matters almost as much as departure conditions. Recheck both ends before you roll.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

What kind of drive is this?

595.5 mi / 11h — a long-haul route where fuel stops, weather, and timing matter more than any single turn. Biggest road: I 10.

95% highway — fuel and pacing are the main things to plan.
26 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 283.4 mi on I 10.

How Hard Is This Drive?

8/10

This is a straightforward highway drive that stays mostly on I 10 and I 75. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes early in the drive near Vincennes Boulevard.

Driving Effort 8/10

Demanding - plan breaks and stay ahead of the key maneuvers

Balances navigation complexity with total wheel time.

This is a demanding drive. With 18 significant decision points across 595.5 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.

Where does it get tricky?

The main spots that need attention: near the start (Vincennes Boulevard): Lane positioning matters here; at 301.7 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 301.8 miles: Highway fork - watch signs carefully. Lane positioning matters here.

Towns Mentioned on Route Signs

Based on OSRM destination-sign hints, not a full list of every settlement the road passes.

On the drive from Cape Coral, FL to Myrtle Grove, FL, road signs begin pointing toward Tallahassee along the way.

Tallahassee

301.7 mi in | ~5h 38m

About the Cities

Starting in Cape Coral, FL

Full guide →

Cape Coral is a city in Southwest Florida. Visitors are drawn by its beaches, nature trails and sea kayaking opportunities on Black Island in Lovers Key State Park.

City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).

Frequently Asked Questions

The longest stretch is about 283.4 miles on I 10. The full list of main roads is in the Roads section above.

Yes — a 2-day pace is more comfortable than one long haul. A sensible stopping point is after roughly 298 miles on day one.

We did not find dedicated rest areas on this route. For a drive this long, plan bathroom and stretch breaks around gas stations, fast-food stops, or small-town downtowns — check the Nearby Places section for options.

It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Myrtle Grove, FL before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.

Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 3 meaningful breaks. Dedicated rest areas are limited, so plan gas or food stops as your bathroom breaks.

The main spots that need attention: near the start (Vincennes Boulevard): Lane positioning matters here; at 301.7 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 301.8 miles: Highway fork - watch signs carefully. Lane positioning matters here.

Not recommended in a single day. At 11.0 hours each way, a round trip means 22.0 hours of driving — that is an unsafe level of fatigue for most drivers. Plan at least one night at Myrtle Grove, FL before the return drive.

How this page is built

Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, NREL for EV charging, and NPS for national parks. See our methodology for refresh cadence and limitations.

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