Planning a trip from Buffalo, NY to DeRuyter, NY? This 172.1-mile journey takes approximately 3 hours and 43 minutes and can easily be completed in a single day. You'll navigate a mix of roads, including the New York State Thruway, Cherry Valley Turnpike, and Clark Street Road. With a fuel cost estimated at $28, this drive offers a straightforward route through the Northeast region. The overall feel is more of a turn-heavy local drive than a pure highway experience, making it a manageable and direct trip.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Break Rhythm
1 planned break
A short stop every 2 to 3 hours is enough for this drive.
Midpoint
86.1 miles from Buffalo, NY
A natural place for your longest stop of the day
, about 1h 43m into the drive
.
Main Roads
Road
Distance
Duration
New York State Thruway
100.9 mi
1h 57m
Cherry Valley Turnpike
18 mi
22m
Clark Street Road
9.6 mi
11m
State Route 80
8.5 mi
12m
Kensington Expressway
6.8 mi
9m
Genesee Street
5.7 mi
10m
Apulia Road
4.3 mi
6m
NY 318
4.1 mi
7m
Longest stretch:
New York State Thruway
— 100.9 mi, about 1h 57m
Turn-by-Turn Driving Directions
Step-by-step road directions between Buffalo, NY and DeRuyter, NY.
1
Start on NY 384
0.1 mi·18 sec·Niagara Square
2
Continue on Court Street
0.2 mi·27 sec·Court Street
3
Continue on Lafayette Square
372 ft·18 sec·Lafayette Square
4
Turn left onto Washington Street
0.2 mi·45 sec·Washington Street
5
Turn right onto Genesee Street
0.3 mi·49 sec·Genesee Street
6
Turn left onto Elm Street
263 ft·7 sec·Elm Street
Use the left lane.
7
Take the exit
0.2 mi·15 sec
Toward NY 33 East
8
Continue on NY 33
6.8 mi·9 min·Kensington Expressway
Use the straight / slight right lanes.
9
Take the exit
0.3 mi·46 sec
Toward I 90 East: Niagara Falls, AlbanyUse the right lane.
10
Merge onto I 90
101 mi·1 hr 57 min·New York State Thruway
Use the straight / right lanes.
11
Take the exit
0.5 mi·58 sec
Exit 41Toward NY 414: Waterloo, ClydeUse the slight right lane.
12
Keep slight right at fork
327 ft·7 sec
13
Continue on NY 414
0.3 mi·35 sec·State Route 414
14
Turn left onto NY 318
4.1 mi·7 min·NY 318
Use the left lane.
15
At end of road, turn left onto US 20; NY 5
1.9 mi·2 min·Auburn Road
16
Continue on US 20; NY 5
9.6 mi·11 min·Clark Street Road
Use the straight lane.
17
Turn right onto State Street
226 ft·12 sec·State Street
18
Turn left onto Dill Street
0.1 mi·21 sec·Dill Street
19
Continue on Loop Road
458 ft·16 sec·Loop Road
20
Turn left onto Genesee Street
5.5 mi·9 min·Genesee Street
21
Continue on US 20
2.3 mi·5 min·West Genesee Street Road
22
Continue on US 20
18 mi·22 min·Cherry Valley Turnpike
Use the straight lane.
23
Turn slight right onto Apulia Road
4.3 mi·6 min·Apulia Road
24
At end of road, turn left onto NY 80
4.4 mi·6 min·State Route 80
25
Continue on NY 80; NY 91
0.7 mi·1 min·Main Street
26
Continue on NY 80
4.1 mi·5 min·State Route 80
27
Continue on NY 80
0.4 mi·29 sec·Fabius Road
28
Turn right onto CR 57
1.6 mi·2 min·Reservoir Road
29
Continue on CR 57
3.0 mi·6 min·East Lake Road
30
At end of road, turn right onto NY 13
1.7 mi·2 min·State Route 13
31
Continue on NY 13
0.3 mi·26 sec·Utica Street
32
Arrive at destination
NY 13
Trip Plan
For this 172.1-mile drive, starting your day with ample daylight will provide the most flexibility. Since it's a one-day trip, you can decide on your pace, but consider making a stop around the halfway point to break up the 3-hour and 43-minute duration. Keep an eye on your fuel, with an estimated cost of $28 for the trip. A specific tip for this route: be mindful of the numerous turns once you leave the New York State Thruway, as the 'turn-heavy' nature means you'll be adjusting your speed and direction more frequently.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 86.1 miles from Buffalo, NY, or about 1h 43m into the drive.
The longest continuous stretch on this route runs about 100.9 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 38 miles or 47m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 86.1 miles or 1h 43m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 2h 57m
Traffic, exits, and arrival timing usually matter more near DeRuyter, NY than in the middle of the route.
Before You Leave
+
Open the route before leaving Buffalo, NY so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Buffalo, NY
This is one driving day of about 172.1 miles and 3h 43m.
Your first comfortable stop window is around 38 miles from Buffalo, NY.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on New York State Thruway for about 100.9 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 17
5 decision points cluster between mile 0.3 and 109.1 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
5
0.3 mi into trip|~1m in|Washington Street
Turn left onto Washington Street
Navigation decision point
6
0.8 mi into trip|~2m in|Elm Street
Turn left onto Elm Street
Lane positioning matters here
Use the left lane.
5
0.9 mi into trip|~2m in
Take the exit toward NY 33 East
Exit ramp - move to the correct lane early
Toward NY 33 East
7
7.9 mi into trip|~12m in
Take the exit toward I 90 East: Niagara Falls, Albany
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the right lane.
Toward I 90 East: Niagara Falls, Albany
8
109.1 mi into trip|~2h 10m in
Take the exit toward NY 414: Waterloo, Clyde
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight right lane.
Exit 41
Toward NY 414: Waterloo, Clyde
Fuel & Cost
Regular Gas
$28.33 one way
$56.66 round trip
$4.18/gal25.4 MPG avg60 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.52
$30.63
$61.26
premium
$4.92
$33.36
$66.71
diesel
$5.61
$38.00
$76.00
Estimated Tolls: $6.31
New York State Thruway
(100.9 mi)$5.05
Cherry Valley Turnpike
(18 mi)$1.26
Toll estimates based on average 2024-2025 rates. EZ-Pass/SunPass discounts may lower the actual cost.
Estimated Trip Cost (one way, 1 person)
Fuel
$28
Tolls
$6
Meals
$25–$50
Total
$60–$85
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 60.2 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $18 in charging
· 0 stops
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
51.6
0
$18.07
$8.26
Efficient EV
43
0
$15.06
$6.88
EV Truck/SUV
68.8
0
$24.09
$11.01
Gas CO2
60 kg
EV CO2
20 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 17, 2026
Origin
Buffalo, NY
Late night
in Buffalo on Tuesday
Local time
5:20 AM
EDT
Current temp
62°F
Partly Sunny
NE 2 mph0% chanceLive forecast
Destination
DeRuyter, NY
Late night
in DeRuyter on Tuesday
Local time
5:20 AM
EDT
Current temp
33°F
Unavailable
Live forecast
60°F
Auburn, NY
86 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
29 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
3h 43m on the road
The weather snapshot is not static. If you are leaving later, give both cities one more quick forecast check before departure.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
Harriet Tubman National Historical Park
National Historical Park
Harriet Tubman was guided by a deep faith and devotion to family, freedom, and community. After emancipating herself and members of her family, she moved them from Ontario, Canada to Fleming and Aubur...
2 mi from route
~4 min detour
Free
near mile 124.6
Women’s Rights National Historical Park tells the story of the first Women’s Rights Convention, held in Seneca Falls, New York on July 19-20, 1848. It is a story of struggles for civil rights, human r...
3 mi from route
~7 min detour
Free
near mile 112.8
Park data from the National Park Service API. Alerts update every 2 hours.
More Details
What kind of drive is this?
This route presents a dynamic driving experience, with only 23% of the journey on highways. Expect a significant portion to be on local roads, indicated by its 'turn-heavy local drive' profile. The longest uninterrupted stretch is 100.9 miles along the New York State Thruway, offering a period of sustained travel before you transition to more varied road conditions. As you progress, the road will likely shift from a more open highway feel to winding through smaller communities and countryside.
Only 23% highway — the rest is turn-by-turn surface driving.
32 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 100.9 mi on New York State Thruway.
How Hard Is This Drive?
6/10
Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. You will hit about 17 points where you need to pay attention to lane position or signs. The trickiest moment comes around 0.3 miles in near Washington Street.
Driving Effort6/10
Moderate - straightforward overall, but long enough or busy enough to require pacing
Balances navigation complexity with total wheel time.
This drive requires moderate attention. Across 172.1 miles you will encounter 17 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.
Where does it get tricky?
The main spots that need attention: at 0.3 miles (Washington Street): Navigation decision point; at 0.8 miles (Elm Street): Lane positioning matters here; at 0.9 miles: Exit ramp - move to the correct lane early.
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
On the drive from Buffalo, NY to DeRuyter, NY, road signs begin pointing toward Clyde along the way.
The largest city in New York State's Niagara Frontier, Buffalo is a city full of surprises. Though Buffalo is sometimes the butt of jokes about chicken wings, its long-suffering sports teams, and the mountains of snow under which it is supposedly buried each winter, those in the know tell a different story: one of vibrant nightlife, world-class museums and cultural attractions, tight-knit neighborhoods with strong community spirit – and the sunniest summers in Northeastern United States.
Top landmarks
•Buffalo AKG Art Museum — art museum in New York, US
•Buffalo City Hall — skyscraper and municipal building in Buffalo, New York, USA
Doable as a same-day drive at 3h 43m. Total distance: 172.1 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
3h 43m drive, comfortable solo distance.
Scenic Drive
Mostly surface roads route profile with national parks nearby.
Frequently Asked Questions
The longest stretch is about 100.9 miles on New York State Thruway. The full list of main roads is in the Roads section above.
Expect about $6.31 in tolls one way, starting with New York State Thruway. Most Northeast and Midwest toll agencies accept E-ZPass; in the West and Texas, transponders like TxTag or FasTrak apply. If you do not have a transponder, cashless tolling plates will mail a bill to the vehicle's registered address — usually with a surcharge, so a rental-car toll pass is often cheaper than paying by mail.
We did not find dedicated rest areas on this route. For a drive this long, plan bathroom and stretch breaks around gas stations, fast-food stops, or small-town downtowns — check the Nearby Places section for options.
It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at DeRuyter, NY before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. Dedicated rest areas are limited, so plan gas or food stops as your bathroom breaks.
The main spots that need attention: at 0.3 miles (Washington Street): Navigation decision point; at 0.8 miles (Elm Street): Lane positioning matters here; at 0.9 miles: Exit ramp - move to the correct lane early.
Yes — Harriet Tubman National Historical Park and Women's Rights National Historical Park. See the National Parks section for detour distances and tips on detours.
Possible but tiring. At 3.7 hours each way, an in-and-out day trip would put you behind the wheel for 7.4 hours — manageable with a long break at DeRuyter, NY, but most travelers stay overnight.
