If you are planning a trip from Brookville to Lafayette, you are looking at a 135.1-mile journey that takes approximately 2 hours and 57 minutes to complete. This route is perfectly suited for a single-day excursion, allowing you to reach your destination without the need for an overnight stay. You can expect to spend roughly $21 on fuel for this trip, making it a fairly budget-friendly Midwestern trek. By combining local roads like Metamora Road with US-52 and I-65, you get a balanced experience of Indiana travel. Whether you are heading out for business or a quick visit, this drive is straightforward and manageable for most drivers.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Break Rhythm
1 planned break
A short stop every 2 to 3 hours is enough for this drive.
Midpoint
67.5 miles from Brookville, IN
A natural place for your longest stop of the day
, about 1h 38m into the drive
.
Main Roads
Road
Distance
Duration
I 65
42.2 mi
45m
Metamora Road
29 mi
42m
United States Highway 52
17.9 mi
26m
East Main Street
14.4 mi
21m
I 465
11.1 mi
12m
I 69
9.8 mi
11m
I 865
5 mi
5m
South Street
2.7 mi
5m
Longest stretch:
I 65
— 42.2 mi, about 45m
Turn-by-Turn Driving Directions
Step-by-step road directions between Brookville, IN and Lafayette, IN.
1
Start on US 52; SR 1
0.3 mi·34 sec·Main Street
2
Turn left onto US 52
29 mi·42 min·Metamora Road
Use the left lane.
3
Turn left onto US 52; SR 44
0.2 mi·21 sec·West 2nd Street
4
Turn slight right onto US 52
0.3 mi·30 sec·West 3rd Street
5
Continue on US 52
18 mi·26 min·United States Highway 52
6
Enter roundabout onto US 52
156 ft·2 sec·East Main Street
7
Continue on US 52
14 mi·21 min·East Main Street
8
Turn left onto US 52
0.4 mi·51 sec·US 52
Toward I 465 North, US 52 WestUse the left lane.
9
Merge onto I 69; I 465
9.8 mi·11 min·I 69; I 465
10
Keep slight left at fork onto I 465
0.3 mi·19 sec·I 465
11
Continue on I-465 WB
0.8 mi·56 sec·I-465 WB
12
Continue on I 465
11 mi·12 min·I 465
Use the straight lane.
13
Keep slight left at fork onto I 865
5.0 mi·5 min·I 865
Exit 25Toward I 865 West: Chicago
14
Merge onto I 65; US 52
12 mi·13 min·I 65; US 52
Use the straight / slight right lanes.
15
Take the exit onto US 52
0.2 mi·15 sec·US 52
Exit 141Toward US 52 West
16
Keep slight left at fork
0.1 mi·9 sec
17
Merge onto I 65
30 mi·32 min·I 65
18
Take the exit
0.2 mi·29 sec
Exit 172Toward SR 26: Lafayette, Rossville
19
Turn left onto SR 26
0.2 mi·23 sec·SR 26
20
Continue on South Street
2.7 mi·5 min·South Street
21
Turn slight left onto Jackson Street
0.1 mi·30 sec·Jackson Street
22
Turn right
178 ft·13 sec
23
Arrive at destination
Trip Plan
To make the most of your 2-hour and 57-minute drive, plan for at least one dedicated stop to break up the transition between local roads and the interstate. Leaving early in the day is your best strategy to avoid any potential congestion on I-65, especially if you are traveling during peak commuting hours. Since you will be navigating a mix of highway types, keep an eye on your fuel gauge before hopping onto the interstate for that 42.2-mile stretch. Flexibility is a major advantage here, as the manageable distance allows you to easily adjust your schedule if you need to linger at your stop. Always double-check your route before leaving Brookville, as the shift from US-52 to I-65 requires careful navigation.
Morning Departure
Leave by 9 AM and you'll arrive before lunch.
Evening Departure
Even a 4 PM departure gets you there before dark in summer.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 67.5 miles from Brookville, IN, or about 1h 38m into the drive.
The longest continuous stretch on this route runs about 42.2 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 30 miles or 44m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 67.5 miles or 1h 38m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 2h 27m
Traffic, exits, and arrival timing usually matter more near Lafayette, IN than in the middle of the route.
Before You Leave
+
Open the route before leaving Brookville, IN so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Brookville, IN
This is one driving day of about 135.1 miles and 2h 57m.
Your first comfortable stop window is around 30 miles from Brookville, IN.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on I 65 for about 42.2 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 14
5 decision points cluster between mile 0.3 and 131.8 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
5
0.3 mi into trip|~0m in|US 52 / Metamora Road
Turn left onto US 52 / Metamora Road
Lane positioning matters here
Use the left lane.
5
47.8 mi into trip|~1h 10m in|US 52 / East Main Street
Enter roundabout onto US 52 / East Main Street
Roundabout - know your exit number before entering
7
62.2 mi into trip|~1h 32m in|US 52
Turn left onto US 52 toward I 465 North, US 52 West
Lane positioning matters here. Multiple destination signs - pick the right one
Use the left lane.
Toward I 465 North, US 52 West
6
84.3 mi into trip|~1h 58m in|I 865
Keep slight left at fork onto I 865 toward I 865 West: Chicago
Highway fork - watch signs carefully
Exit 25
Toward I 865 West: Chicago
6
131.8 mi into trip|~2h 50m in
Take the exit toward SR 26: Lafayette, Rossville
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Exit 172
Toward SR 26: Lafayette, Rossville
Fuel & Cost
Regular Gas
$21.12 one way
$42.24 round trip
$3.97/gal25.4 MPG avg47 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.36
$23.19
$46.38
premium
$4.89
$26.00
$52.00
diesel
$5.61
$29.83
$59.66
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$21
Meals
$25–$50
Total
$46–$71
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 47.3 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $14 in charging
· 0 stops
· 66% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
40.5
0
$14.19
$6.48
Efficient EV
33.8
0
$11.82
$5.40
EV Truck/SUV
54
0
$18.91
$8.65
Gas CO2
47 kg
EV CO2
16 kg (66% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 13, 2026
Origin
Brookville, IN
Late night
in Brookville on Tuesday
Local time
5:03 AM
EDT
Current temp
65°F
Chance Rain Showers
SW 7 to 10 mph50% chanceLive forecast
Special Weather Statement
Special Weather Statement issued April 12 at 10:19PM CDT by NWS Chicago IL
Flood Warning
Flood Warning issued April 12 at 10:34PM EDT until April 16 at 2:00AM EDT by NWS Northern Indiana
Destination
Lafayette, IN
Late night
in Lafayette on Tuesday
Local time
5:03 AM
EDT
Current temp
64°F
Chance Rain Showers
SW 14 to 20 mph63% chanceLive forecast
Special Weather Statement
Special Weather Statement issued April 12 at 10:19PM CDT by NWS Chicago IL
Flood Warning
Flood Warning issued April 12 at 10:34PM EDT until April 16 at 2:00AM EDT by NWS Northern Indiana
69°F
Lawrence, IN
68 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
1 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
2h 57m on the road
The weather snapshot is not static. If you are leaving later, give both cities one more quick forecast check before departure.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
More Details
What kind of drive is this?
This highway-focused drive is comprised of about 65% major roadways, creating a mix of local navigation and steady interstate cruising. You will start on secondary roads before transitioning to the faster pace of I-65, where you will encounter your longest uninterrupted stretch of 42.2 miles. Expect the character of the road to shift significantly as you move away from Metamora Road and merge into the flow of high-speed highway traffic. While portions of the route demand your full attention on local paths, the interstate segments provide a consistent rhythm for the majority of the drive. It is a practical route that favors efficiency over scenic detours.
65% highway — fuel and pacing are the main things to plan.
23 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 42.2 mi on I 65.
How Hard Is This Drive?
8/10
This is a straightforward highway drive that stays mostly on I 65 and Metamora Road. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 0.3 miles in near US 52 / Metamora Road.
Driving Effort8/10
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 14 significant decision points across 135.1 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 0.3 miles (US 52 / Metamora Road): Lane positioning matters here; at 47.8 miles (US 52 / East Main Street): Roundabout - know your exit number before entering; at 62.2 miles (US 52): Lane positioning matters here. Multiple destination signs - pick the right one.
Lafayette is the county seat of Tippecanoe County, Central Indiana. It is located 2 hours southeast of Chicago and 1 hour northwest of Indianapolis. The Greater Lafayette metropolitan area consists of the cities of Lafayette and West Lafayette. The combined population is 97,000. Neighboring West Lafayette is home to Purdue University, a large, prestigious public university.
Doable as a same-day drive at 2h 57m. Total distance: 135.1 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
2h 57m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (65%). Some complex stretches to watch for.
Frequently Asked Questions
The longest stretch is about 42.2 miles on I 65. The full list of main roads is in the Roads section above.
It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Lafayette, IN before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. Dedicated rest areas are limited, so plan gas or food stops as your bathroom breaks.
The main spots that need attention: at 0.3 miles (US 52 / Metamora Road): Lane positioning matters here; at 47.8 miles (US 52 / East Main Street): Roundabout - know your exit number before entering; at 62.2 miles (US 52): Lane positioning matters here. Multiple destination signs - pick the right one.
Yes. A round trip is manageable in a single day if you plan a break at Lafayette, IN before heading back.
