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Road Trips from Cape Girardeau, MO

You're looking to get out of Cape Girardeau this weekend. With options ranging from a quick 45-minute drive to a longer 6-hour haul, you can choose your own adventure. Most routes stick to flat terrain and highway driving, making for straightforward trips. You've got several destinations within a 2-hour radius, several of which offer access to national parks, plus a few further afield if you're looking for a more substantial drive.

Total Routes

7

Shortest

5.4h

With Parks Nearby

7

Weekend trip

7 total in this range

Browse by Mood

When to Go

Spring

Spring offers pleasant driving conditions on flat terrain, with parks like Ste. Geneviève National Historical Park accessible for exploration.

Summer

The mostly highway routes are suitable for summer travel, with national parks remaining open for visits.

Fall

Fall foliage can enhance drives through the flat terrain, and national park sites offer outdoor activities.

Winter

Winter drives on the mostly highway routes are feasible, though park accessibility may vary.

Starting Somewhere Else?

Other nearby cities with their own escape planners.

Ready to plan?

Pick any destination above for full turn-by-turn directions, fuel cost, rest stops, and weather. Or visit the Cape Girardeau, MO city hub for all incoming and outgoing routes.