Drive or Fly: Loretto, TN to Knoxville, TN?
Side-by-side comparison of driving versus flying for this route. Costs, time, and trade-offs at a glance.
Driving wins
MediumNo scheduled commercial flights found for MSL–TYS. At 270 miles, driving is the only practical option.
Find Your Vehicle (EPA fuel economy data)
· · Fuel cost: $
Drive
Door to Door
5h
Distance
270.6 mi
Total Cost
$95
CO2
109 kg
Cost Breakdown
Fly
Door to Door
3h 20m
25m in the air
Air Distance
207 mi
Total Cost
$183
CO2
53 kg
Door-to-Door Timeline
Cost Breakdown
Airports
No scheduled flights found
No commercial flights between MSL and TYS. Flight estimates above are theoretical.
At a Glance
| Drive | Fly | |
|---|---|---|
| Door-to-door time | 5h | 3h 20m |
| Total cost (1 person) | $95 | $183 |
| Carbon footprint | 109 kg CO2 | 53 kg CO2 |
| Flexibility | High | Low |
| Luggage | Unlimited | Restricted |
| Reliability | Weather dependent | Data unavailable |
Costs are estimates. Actual flight prices vary by airline, date, and booking time. Drive costs based on OSRM routing, EIA fuel prices. Computed Apr 21, 2026.
Route Options
2 different routes between these cities.
via I 40, US 43, I 840
via I 75, US 64, I 24; US 64
Decided to drive? See the full trip plan from Loretto, TN to Knoxville, TN with stops, fuel costs, and turn-by-turn directions.